IndraLab

Statements

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"Further in vitro cell experiments revealed that hsa_circ_0013880-mediated elevation of USP32 promoted cell proliferation and migration and reduced cell apoptosis."
36951484
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"We carried out a number of rescue studies to look into the possibility that BAG3 is involved in USP32-mediated NSCLC cell proliferation, migration, and EMT."
39030175
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"Namely, we found that USP32 knockdown effectively inhibited HL-60 and U937 cell proliferation, arrested the cell cycle at G1 phase, and induced cell apoptosis."
36951484
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"USP32 promotes NSCLC cell proliferation and migration."
39030175
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"USP32 depletion dramatically decreased the proliferation of A549 and H1299 cells, according to the results of the Cell Counting Kit-8 (CCK8) experiment (Fig. 2C)."
39030175
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"All of these findings demonstrate that USP32 increases the proliferation and migration process of NSCLC cells."
39030175
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"Results of CCK-8 and plate cloning experiments showed that USP32 depletion inhibited NSCLC cell lines growth and single cell clone formation, while further overexpression of BAG3 reversed NSCLC cell lines proliferation inhibition by USP32 knockdown (Fig. 5C, D)."
39030175
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"In the present study, we reported that knockdown or depletion of USP32 significantly inhibited GC cell proliferation and migration in vitro and in vivo, indicating that USP32 functions as an oncogene in GC."
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"On the other hand, downregulation of USP32 in vitro caused reduced migration and proliferation rates of SCLC cells."
30760385
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"siRNA-directed USP32 inhibition significantly decreased cell proliferation/survival in vitro ( Fig. S1A, B , Fig. 2 A, B, and C)."
33744759
USP32 affects BAG3
| 13 3
USP32 binds BAG3.
| 4 3
USP32 binds BAG3. 4 / 4
| 4
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"To further elucidate the mechanism of action of USP32 in NSCLC, we screened H1299 cells for interacting proteins and found that USP32 interacts with BAG3 (Bcl2-associated athanogene 3) and deubiquitinates and stabilizes BAG3 in a deubiquitinating activity-dependent manner."
39030175
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"This suggests a possible interaction between BAG3 (yellow protein) and USP32 (blue protein)."
39030175
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"Given that USP32 is a DUB, we first performed an organizing and query analysis of the TCGA database to investigate the association between USP32 and BAG3."
39030175
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"However, the role of deubiquitinating enzymes in the regulation of BAG3 is unclear.In this study, we know from immunofluorescence co-localization experiments that USP32 co-localizes with BAG3 in the cytoplasm, and that USP32 can directly bind to BAG3 by exogenous and exogenous immunoprecipitation."
39030175
BAG3 binds USP32. 3 / 3
| 3
sparser
"Finally, in order to investigate the relationship between USP32-BAG3, we first found that USP32 was positively correlated with the mRNA expression of BAG3 by analyzing the TCGA database, after which their positive correlation in protein levels was verified in various cell lines of NSCLC."
39030175
sparser
"Finally, we detected and analyzed USP32-BAG3 expression and clinical correlation in human NSCLC tissues and paracancerous noncancerous tissues."
39030175
sparser
"In this study, we know from immunofluorescence co-localization experiments that USP32 co-localizes with BAG3 in the cytoplasm, and that USP32 can directly bind to BAG3 by exogenous and exogenous immunoprecipitation."
39030175
USP32 increases the amount of BAG3.
| 3
USP32 increases the amount of BAG3. 3 / 3
| 3
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"USP32 activates the RAF/MEK/ERK signaling pathway by regulating BAG3 expression."
39030175
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"USP32 interacts with BAG3 and upregulates the protein level of BAG3."
39030175
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"The above data proved that USP32 interacts with BAG3 and positively regulates BAG3 protein level."
39030175
USP32 activates BAG3.
| 3
USP32 activates BAG3. 3 / 3
| 3
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"Mechanistic investigations revealed that BAG3 is a substrate for USP32, and that USP32 directly interacts with BAG3 to promote NSCLC carcinogenesis through blocking BAG3 degradation."
39030175
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"We then looked at whether USP32 inhibited BAG3 degradation in a way that was dependent on proteasomes."
39030175
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"The findings demonstrated that USP32 overexpression in H1299 cells extended the BAG3 protein’s half-life (Fig. 4A), while USP32 knockdown accelerated the degradation of BAG3 in A549 cells (Fig. 4B)."
39030175
USP32 deubiquitinates BAG3.
| 2
USP32 deubiquitinates BAG3. 2 / 2
| 2
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"To investigate whether USP32 deubiquitinates BAG3, Myc-USP32 plasmids or a control vector were used to co-transfect Flag-BAG3 and HA-ubiquitin into H1299 cells."
39030175
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"The findings demonstrated that whereas BAG3 ubiquitination in cells transfected with K48-linked ubiquitin chains was considerably reduced by USP32, it was unaffected in cells transfected with HA-K63-linked ubiquitin chains (Fig. 4H)."
39030175
USP32 inhibits BAG3.
| 1
USP32 inhibits BAG3. 1 / 1
| 1
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"The outcomes of the experiment demonstrated that BAG3’s degree of ubiquitination was greatly decreased by USP32 overexpression (Fig. 4G)."
39030175
USP32 affects RAB7A
1 | 14
USP32 deubiquitinates RAB7A.
| 7
USP32 deubiquitinates RAB7A. 6 / 6
| 6
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"25 To confirm that Rab7 is deubiquitinated by USP32, Rab7 ubiquitination was monitored in the presence and absence of exogenous USP32."
36476874
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"11 Their data also showed that USP32 deubiquitinates Rab7, which impacts binding efficiency of the small GTPase to different effector proteins and thereby regulates Rab7 function."
36476874
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"13 Loss of USP32 increased ubiquitination of Rab7 at K191/194, which enhanced binding of Rab7 to its effector protein RILP and accelerated retrograde transport of CI-MPR."
36476874
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"Having established that USP32 can deubiquitylate Rab7 in vitro and in situ, we sought to understand the interplay between USP32 and Rab7 in endosome biology."
30926795
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"This suggested that deubiquitylation of Rab7 by USP32 promotes release of Rab7 from the membrane to the cytosol, where a new functional cycle of this Rab can commence (Fig. 5i)."
30926795
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"Taken together with the observations on endosomal transport (Fig. 6), these findings support a model wherein deubiquitylation of Rab7 by USP32 exerts multifaceted control over membrane dynamics at the LE/MVB by promoting their intracellular motility as well as enabling efficient recycling from these organelles (Fig. 9)."
30926795
USP32 deubiquitinates RAB7A on K191. 1 / 1
| 1
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"Cellular ubiquitome profiling revealed deubiquitylation of Rab7 by USP32 on K191, located in the solvent-exposed flexible C-terminal region of the molecule."
30926795
USP32 activates RAB7A.
| 4
USP32 activates RAB7A. 4 / 4
| 4
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"Taken together, our data indicated that Rab7 function can be modulated by USP32-sensitive ubiquitination and that USP32 deficiency resulted in altered retromer-mediated trafficking and autophagy induc[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
36476874
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"Indeed, USP32 depletion sequesters Rab7 in abnormally enlarged endosomal structures, and the accumulation of ubiquitinylated Rab7 promotes interactions with the retromer and inhibits interactions with RILP [29]."
32033485
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"Using proteome-wide ubiquitin remnant profiling, we reveal Rab7 to be a key substrate of USP32 and go on to show that USP32 supports Rab7 functions in transport and recycling from the MVB by two different mechanisms."
30926795
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"Secondly, USP32 supports the role of Rab7 in the transport and circulation of MVB through two different mechanisms [35]."
37679322
USP32 ubiquitinates RAB7A.
| 2
USP32 leads to the ubiquitination of RAB7A. 2 / 2
| 2
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"Additionally, studies have indicated that the deubiquitinating enzyme USP32 enables non-ubiquitinated RAB7A to effectively mediate the minus-end transport of late endosomes (nuclear transport)."
39663592
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"Ubiquitination of RAB7A has been shown to be mediated by PRKN/parkin (an E3 ubiquitin ligase) and USP32, both of which target lysine K38 on RAB7A [32,34]."
39663592
USP32 increases the amount of RAB7A.
| 1
USP32 increases the amount of RAB7A. 1 / 1
| 1
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"This suggested that deubiquitylation of Rab7 by USP32 promotes release of Rab7 from the membrane to the cytosol, where a new functional cycle of this Rab can commence (Fig. 5i)."
30926795
USP32 binds RAB7A.
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RAB7A binds USP32. 1 / 1
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biogrid
No evidence text available
34432599
USP32 affects RAP1B
1 | 9 1
USP32 activates RAP1B.
| 5
USP32 activates RAP1B. 5 / 5
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"Given the deubiquitination function of USP32, we further hypothesize that USP32 may mediate the malignant behaviors of AML cells by regulating the stability of Ras-related protein (Rap1b)."
36951484
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"Given the deubiquitination function of USP32, we then reasonably hypothesized that USP32 might contribute to the progression of AML by stabilizing Ras-related protein (Rap1b)."
36951484
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"Knockdown of USP32 reduced the stability of the Rap1b protein ."
36951484
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"Accordingly, we demonstrated that knockdown of USP32 could reduce the stability of the Rap1b protein."
36951484
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"USP32 promotes the malignant behaviors of acute myeloid leukemia cells by regulating the stability of Rap1b [12]."
40136417
USP32 binds RAP1B.
1 | 1 1
RAP1B binds USP32. 2 / 2
1 | 1
biogrid
No evidence text available
26496610
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"USP32 could interact with Rap1b and stabilize Rap1b."
37679322
USP32 binds RAP1B. 1 / 1
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sparser
"USP32 could interact with Rap1b and stabilize Rap1b."
37679322
USP32 ubiquitinates RAP1B.
| 1
USP32 leads to the ubiquitination of RAP1B. 1 / 1
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"At the molecular level, we find that silencing of USP32 increases ubiquitinated Rap1b."
36951484
USP32 increases the amount of RAP1B.
| 1
USP32 increases the amount of RAP1B. 1 / 1
| 1
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"Knockdown of USP32 in HL-60 and U937 cells significantly reduced the expression of Rap1b."
37679322
USP32 decreases the amount of RAP1B.
| 1
USP32 decreases the amount of RAP1B. 1 / 1
| 1
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"Herein, our results showed that silencing of USP32 could increase the ubiquitination level of Rap1b."
36951484
USP32 affects NFE2L2
| 7 3
USP32 binds NFE2L2.
| 1 3
USP32 binds NFE2L2. 3 / 3
| 3
sparser
"Moreover, the Co-IP results indicated the direct association of USP32 with NRF2, suggesting that USP32 may be a deubiquitinase of NRF2."
40136417
sparser
"Taken together, these results revealed that LBT triggered ferroptosis in LUSC cells in vivo by targeting the USP32–NRF2 axis."
40136417
sparser
"Furthermore, the results of the Co-IP analysis also revealed a strong interaction between USP32 and NRF2 ( xref B)."
40136417
USP32 binds NFE2L2. 1 / 1
| 1
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"Furthermore, the results of the Co-IP analysis also revealed a strong interaction between USP32 and NRF2 (Figure 4B)."
40136417
USP32 deubiquitinates NFE2L2.
| 3
USP32 leads to the deubiquitination of NFE2L2. 3 / 3
| 3
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"Thus, we further assessed whether USP32 could inhibit the ubiquitination of NRF2 caused by Keap1 and whether LBT could promote the ubiquitination of NRF2 by targeting USP32."
40136417
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"Therefore, we tried to demonstrate whether USP32 inhibits the ubiquitination of NRF2 caused by Keap1 and whether LBT enhances the ubiquitination and degradation of NRF2 by targeting USP32 to induce ferroptosis."
40136417
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"The results demonstrated that USP32 markedly inhibited Keap1-mediated NRF2 ubiquitination, whereas LBT treatment effectively reversed the deubiquitination of NRF2 mediated by USP32 (Figure 4D)."
40136417
USP32 increases the amount of NFE2L2.
| 2
USP32 increases the amount of NFE2L2. 2 / 2
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"We found that USP32 overexpression increased NRF2 protein levels in LUSC cells (Figure 5A)."
40136417
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"In our study, we found that USP32 markedly inhibited Keap1-mediated NRF2 ubiquitination and that USP32 overexpression markedly increased NRF2 protein levels, which demonstrated that USP32 is a DUB of NRF2."
40136417
USP32 ubiquitinates NFE2L2.
| 1
USP32 leads to the ubiquitination of NFE2L2. 1 / 1
| 1
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"The results demonstrated that USP32 markedly inhibited Keap1-mediated NRF2 ubiquitination, whereas LBT treatment effectively reversed the deubiquitination of NRF2 mediated by USP32 (Figure 4D)."
40136417
USP32 affects LAMTOR1
1 | 8
USP32 deubiquitinates LAMTOR1.
| 4
USP32 deubiquitinates LAMTOR1. 2 / 2
| 2
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"In the presence of inactive USP32 (C743S) binding of LAMTOR1 to multiple v-ATPase subunits was significantly reduced, which suggests that USP32 needs to deubiquitinate LAMTOR1 for its efficient intera[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
36476874
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"37 , 38 , 39 Knockdown of USP32 caused accumulation of TFEB in the nucleus as compared with cells transfected with non-targeting control siRNAs ( Figures 5 E and 5F), suggesting reduced mTORC1 activit[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
36476874
USP32 deubiquitinates LAMTOR1 at position 20. 1 / 1
| 1
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"Our data showed that USP32 controls Ragulator function by deubiquitinating LAMTOR1 at lysine residue 20 (K20), thereby promoting the interaction between the lysosomal v-ATPase and LAMTOR1."
36476874
USP32 deubiquitinates LAMTOR1 on lysine. 1 / 1
| 1
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"Our data showed that USP32 controls Ragulator function by deubiquitinating LAMTOR1 at lysine residue 20 (K20), thereby promoting the interaction between the lysosomal v-ATPase and LAMTOR1."
36476874
USP32 ubiquitinates LAMTOR1.
| 2
USP32-C743S leads to the ubiquitination of LAMTOR1. 1 / 1
| 1
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"Co-expression of catalytic inactive USP32 (C743S) moderately increased LAMTOR1 ubiquitination as compared with WT USP32.Recently, the E3 ubiquitin ligase UBE3A has been shown to target LAMTOR1 for pro[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
36476874
USP32 ubiquitinates LAMTOR1 on K20. 1 / 1
| 1
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"34 However, abundance of LAMTOR1 was not affected in USP32 KO cells ( Figure 1 E), suggesting that enriched USP32-sensitive ubiquitination of LAMTOR1 at K20 does not promote its proteasomal degradatio[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
36476874
USP32 inhibits LAMTOR1.
| 1
USP32 inhibits LAMTOR1. 1 / 1
| 1
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"Recently, we identified a non-proteolytic ubiquitin signal at the Ragulator complex subunit LAMTOR1 that is reversed by the deubiquitinase USP32."
36847417
USP32 binds LAMTOR1.
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LAMTOR1 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
34079125
USP32 activates LAMTOR1.
| 1
USP32-C743S activates LAMTOR1. 1 / 1
| 1
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"Co-expression of catalytic inactive USP32 (C743S) moderately increased LAMTOR1 ubiquitination as compared with WT USP32.Recently, the E3 ubiquitin ligase UBE3A has been shown to target LAMTOR1 for pro[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
36476874
BAG3 affects USP32
| 6 3
BAG3 binds USP32.
| 4 3
USP32 binds BAG3. 4 / 4
| 4
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"To further elucidate the mechanism of action of USP32 in NSCLC, we screened H1299 cells for interacting proteins and found that USP32 interacts with BAG3 (Bcl2-associated athanogene 3) and deubiquitinates and stabilizes BAG3 in a deubiquitinating activity-dependent manner."
39030175
reach
"This suggests a possible interaction between BAG3 (yellow protein) and USP32 (blue protein)."
39030175
reach
"Given that USP32 is a DUB, we first performed an organizing and query analysis of the TCGA database to investigate the association between USP32 and BAG3."
39030175
reach
"However, the role of deubiquitinating enzymes in the regulation of BAG3 is unclear.In this study, we know from immunofluorescence co-localization experiments that USP32 co-localizes with BAG3 in the cytoplasm, and that USP32 can directly bind to BAG3 by exogenous and exogenous immunoprecipitation."
39030175
BAG3 binds USP32. 3 / 3
| 3
sparser
"Finally, in order to investigate the relationship between USP32-BAG3, we first found that USP32 was positively correlated with the mRNA expression of BAG3 by analyzing the TCGA database, after which their positive correlation in protein levels was verified in various cell lines of NSCLC."
39030175
sparser
"Finally, we detected and analyzed USP32-BAG3 expression and clinical correlation in human NSCLC tissues and paracancerous noncancerous tissues."
39030175
sparser
"In this study, we know from immunofluorescence co-localization experiments that USP32 co-localizes with BAG3 in the cytoplasm, and that USP32 can directly bind to BAG3 by exogenous and exogenous immunoprecipitation."
39030175
BAG3 activates USP32.
| 2
BAG3 activates USP32. 2 / 2
| 2
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"Functionally, restoration of BAG3 expression abrogated the antitumor effects of USP32 silencing."
39030175
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"BAG3 overexpression in NSCLC reverse the antitumor effect of USP32 deletion."
39030175
USP32 affects apoptotic process
| 8
USP32 inhibits apoptotic process.
| 5
USP32 inhibits apoptotic process. 5 / 5
| 5
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"USP32 knockdown increased apoptosis in addition to causing cell cycle arrest in the G0/G1 phase, with concomitant increases in Caspase3, cleaved PARP and P53-related apoptotic proteins."
37679322
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"However, USP32 knockdown promoted cell apoptosis in hsa_circ_0013880-overexpressing cells."
36951484
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"Knockdown of USP32 promoted apoptosis in AML cells ."
36951484
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"These findings indicated that knockdown of USP32 could promote the apoptosis of HL-60 and U937 cells."
36951484
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"Overexpression of Rap1b largely reversed USP32 knockdown-induced apoptosis."
37679322
USP32 activates apoptotic process.
| 3
USP32 activates apoptotic process. 3 / 3
| 3
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"Namely, we found that USP32 knockdown effectively inhibited HL-60 and U937 cell proliferation, arrested the cell cycle at G1 phase, and induced cell apoptosis."
36951484
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"In addition, downregulation of USP32 significantly induced cell apoptosis by activating cleaved caspase-3 and cleaved PARP, as well as inhibiting cell invasiveness via altering epithelial mesenchymal transition expression."
28597490
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"Moreover, USP32 was found to be overexpressed in human small cell lung cancer tissues, and USP32 silencing significantly suppressed small cell lung cancer cells proliferation and migration, cell cycle progression arrested and cell apoptosis (35)."
35116927
USP32 affects RAB35
5 | 1 2
USP32 binds RAB35.
5 | 2
RAB35 binds USP32. 5 / 5
5 |
biogrid
No evidence text available
36725886
biogrid
No evidence text available
36725886
biogrid
No evidence text available
36725886
biogrid
No evidence text available
36725886
biogrid
No evidence text available
36725886
RAB35 binds USP32. 2 / 2
| 2
sparser
"Recent research has revealed that the USP32-Rab35 axis is crucial for controlling treatment resistance in gastrointestinal stromal tumors."
37679322
sparser
"Their research suggests that individuals with gastrointestinal stromal tumors resistant to imatinib may benefit from focusing on the USP32-Rab35 axis as a potential therapeutic target."
37679322
USP32 deubiquitinates RAB35.
| 1
USP32 deubiquitinates RAB35. 1 / 1
| 1
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"Deubiquitylation of Rab35 by USP32 promotes the transmission of imatinib resistance by enhancing exosome secretion in gastrointestinal stromal tumours."
36725886
USP32 is modified
7 | 1
USP32 is phosphorylated.
7 |
USP32 is phosphorylated on S1372. 2 / 2
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hprd
No evidence text available
19651622
hprd
No evidence text available
17081983
USP32 is phosphorylated on S1361. 2 / 2
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hprd
No evidence text available
19651622
hprd
No evidence text available
17081983
USP32 is phosphorylated on S1366. 1 / 1
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hprd
No evidence text available
19651622
USP32 is phosphorylated on S1423. 1 / 1
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hprd
No evidence text available
19664995
USP32 is phosphorylated on Y1173. 1 / 1
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hprd
No evidence text available
18669648
USP32 is ubiquitinated.
| 1
USP32 is ubiquitinated. 1 / 1
| 1
sparser
"In our study, we found that USP32 markedly inhibited Keap1-mediated NRF2 ubiquitination and that USP32 overexpression markedly increased NRF2 protein levels, which demonstrated that USP32 is a DUB of NRF2."
40136417
RAP1B affects USP32
1 | 5 1
RAP1B inhibits USP32.
| 3
RAP1B inhibits USP32. 3 / 3
| 3
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"CCK-8 assays confirmed that overexpression of Rap1b increased the viability of USP32-silenced HL-60 cells ( Figure 7C)."
36951484
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"However, Rap1b overexpression restored the effects of USP32 silencing."
36951484
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"Overexpression of Rap1b restores the effects of USP32 knockdown, which further verifies our hypothesis."
36951484
RAP1B binds USP32.
1 | 1 1
RAP1B binds USP32. 2 / 2
1 | 1
biogrid
No evidence text available
26496610
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"USP32 could interact with Rap1b and stabilize Rap1b."
37679322
USP32 binds RAP1B. 1 / 1
| 1
sparser
"USP32 could interact with Rap1b and stabilize Rap1b."
37679322
RAP1B activates USP32.
| 1
RAP1B activates USP32. 1 / 1
| 1
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"However, overexpression of Rap1b significantly attenuated the beneficial effects of USP32 knockdown on AML cells, implying that knockdown of USP32 could inhibit the growth of HL-60 cells via regulation of Rap1b expression."
36951484
RAB35 affects USP32
5 | 2
RAB35 binds USP32. 5 / 5
5 |
biogrid
No evidence text available
36725886
biogrid
No evidence text available
36725886
biogrid
No evidence text available
36725886
biogrid
No evidence text available
36725886
biogrid
No evidence text available
36725886
RAB35 binds USP32. 2 / 2
| 2
sparser
"Recent research has revealed that the USP32-Rab35 axis is crucial for controlling treatment resistance in gastrointestinal stromal tumors."
37679322
sparser
"Their research suggests that individuals with gastrointestinal stromal tumors resistant to imatinib may benefit from focusing on the USP32-Rab35 axis as a potential therapeutic target."
37679322
LBT affects USP32
| 7
LBT binds USP32.
| 3
LBT binds USP32. 3 / 3
| 3
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"CETSA was further performed to validate the interaction between LBT and USP32."
40136417
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"As expected, the heat challenge quickly led to USP32 denaturation and precipitation, while LBT markedly increased the thermal stability of the USP32 protein at temperatures ranging from 42 °C to 54 °C (Figure 3F), confirming the direct binding of LBT to USP32."
40136417
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"Firstly, molecular docking and molecular dynamic simulations were conducted to estimate the interaction between LBT and USP32."
40136417
LBT activates USP32.
| 3
LBT activates USP32. 3 / 3
| 3
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"Taken together, these results revealed that LBT triggered ferroptosis in LUSC cells in vivo by targeting the USP32–NRF2 axis."
40136417
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"As expected, the heat challenge quickly led to USP32 denaturation and precipitation, while LBT markedly increased the thermal stability of the USP32 protein at temperatures ranging from 42 °C to 54 °C (Figure 3F), confirming the direct binding of LBT to USP32."
40136417
reach
"To validate whether LBT induces ferroptosis by targeting USP32, we established the stable overexpression of USP32 in H520 and H1703 cells using lentivirus infection."
40136417
LBT decreases the amount of USP32.
| 1
LBT decreases the amount of USP32. 1 / 1
| 1
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"Additionally, we found that LBT treatment obviously decreased the protein expression levels of USP32 and NRF2 in LUSC cells (Figure 4C)."
40136417
USP32 affects Neoplasm Metastasis
| 1 5
USP32 activates Neoplasm Metastasis.
| 1 3
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"Additionally, USP32 promotes GC cell growth, metastasis, and chemoresistance by upregulating SMAD2, an important protein in the TGF-β signaling pathway [55]."
36497313
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"So far, it has been reported that USP32 was over-expressed in lung and breast cancers, enhancing cellular proliferation and tissue metastasis (9)."
37210642
eidos
"USP32 downregulation inhibited cell growth and metastasis in vitro ."
35440702
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"Similarly, USP32 knockdown by shRNA significantly impaired peritoneal metastasis in a xenograft assay ( Fig. S1C , Fig. 2 D), confirming that USP32 inhibition exerted antitumor effects in vitro and in[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
33744759
USP32 inhibits Neoplasm Metastasis.
| 2
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"USP32 downregulation inhibited cell growth and metastasis in vitro."
35440702
reach
"In this study, markedly high USP32 expression in peritoneal tumors of EOC, its negative impact on survival outcome, and antitumor effect upon USP32 inhibition to suppress peritoneal metastasis suggest[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
33744759
MicroRNAs affects USP32
| 6
MicroRNAs decreases the amount of USP32.
| 5
MicroRNAs decreases the amount of USP32. 5 / 5
| 5
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"As a result, miR let-7a might suppress the expression of USP32 protein by directly binding to the USP32 3’UTR."
37679322
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"Western blot analysis revealed that miR let-7a mimics dramatically decreased the USP32 protein expression, whereas miR let-7a inhibitors increased the protein expression of USP32 compared with their controls in the MCF-7 cells."
35116927
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"There has been no data showing the correlations between the expression of USP32 and miRNA.To validate whether USP32 protein expression is downregulated by miR let-7a, we examined the level of USP32 protein after transfecting miR let-7a mimics and inhibitors."
35116927
reach
"Taken together, these results confirmed that miR let-7a can inhibit USP32 protein expression level by directly binding USP32 3'UTR.Our present results showed that USP32 expression is up-regulated in human BCa cells and miR let-7a significantly inhibits USP32 expression."
35116927
reach
"Collectively, the results demonstrated that miR let-7a could downregulate the protein levels of USP32 in MCF-7 cells."
35116927
MicroRNAs increases the amount of USP32.
| 1
MicroRNAs increases the amount of USP32. 1 / 1
| 1
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"Taken together, the results suggest that miR let-7a could increase cellular ubiquitination by decreasing the expression of USP32."
35116927
Rep affects USP32
5 |
Rep binds USP32. 5 / 5
5 |
biogrid
No evidence text available
| DOI
biogrid
No evidence text available
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biogrid
No evidence text available
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biogrid
No evidence text available
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biogrid
No evidence text available
| DOI
USP32 affects SLC35F2
| 4 1
USP32 inhibits SLC35F2.
| 2
USP32 inhibits SLC35F2. 1 / 1
| 1
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"Loss of USP32 enhances SLC35F2-mediated YM155-induced DNA damage and response [ 30 ]."
37801987
USP32 bound to SLC35F2 inhibits SLC35F2. 1 / 1
| 1
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"Researchers further found that the direct binding of USP32 and SLC35F2 in the endoplasmic reticulum could negatively regulate the stability of SLC35F2 and promote drug resistance to YM155 in breast cancer cells [32] (Fig. 6)."
37679322
USP32 binds SLC35F2.
| 1 1
USP32 binds SLC35F2. 1 / 1
| 1
reach
"Researchers further found that the direct binding of USP32 and SLC35F2 in the endoplasmic reticulum could negatively regulate the stability of SLC35F2 and promote drug resistance to YM155 in breast cancer cells [32] (Fig. 6)."
37679322
USP32 binds SLC35F2. 1 / 1
| 1
sparser
"Researchers further found that the direct binding of USP32 and SLC35F2 in the endoplasmic reticulum could negatively regulate the stability of SLC35F2 and promote drug resistance to YM155 in breast cancer cells [ xref ] (Fig. xref )."
37679322
USP32 decreases the amount of SLC35F2.
| 1
USP32 decreases the amount of SLC35F2. 1 / 1
| 1
reach
"Therefore, inhibition of USP32 can increase the protein expression of SLC35F2 and improve the chemotherapeutic effect of YM155 on breast cancer, opening up a new pathway for clinical drug resistance treatment."
37679322
USP32 affects RAF/MEK/ERK
| 5
USP32 activates RAF/MEK/ERK.
| 4
USP32 activates RAF/MEK/ERK. 4 / 4
| 4
reach
"Therefore, by deubiquitinating BAG3, we can show that USP32 can activate the RAF/MEK/ERK pathway.Finally, in order to investigate the relationship between USP32-BAG3, we first found that USP32 was positively correlated with the mRNA expression of BAG3 by analyzing the TCGA database, after which their positive correlation in protein levels was verified in various cell lines of NSCLC."
39030175
reach
"We conducted rescue studies in A549 and H1299 cells by transfecting with siControl or siUSP32 for 24 h, followed by transfecting with Flag or Flag-BAG3 to examine whether USP32 activates the RAF/MEK/ERK signaling cascade by increasing BAG3 expression in NSCLC cells."
39030175
reach
"In summary, these findings support our theory that USP32 regulates the level of BAG3 protein to activate the RAF/MEK/ERK signaling pathway."
39030175
reach
"These experimental results suggest that USP32 activates the RAF/MEK/ERK signaling pathway, which in turn promotes NSCLC cell proliferation, migration, and EMT progression through deubiquitination and stabilization of BAG3."
39030175
USP32 increases the amount of RAF/MEK/ERK.
| 1
USP32 increases the amount of RAF/MEK/ERK. 1 / 1
| 1
reach
"Furthermore, USP32 increased the phosphorylation level of the RAF/MEK/ERK signaling pathway in NSCLC cells by stabilizing BAG3."
39030175
USP32 affects Carcinogenesis
| 1 4
USP32 activates Carcinogenesis. 5 / 5
| 1 4
reach
"Mechanistic investigations revealed that BAG3 is a substrate for USP32, and that USP32 directly interacts with BAG3 to promote NSCLC carcinogenesis through blocking BAG3 degradation."
39030175
reach
"These observations suggest that SMAD2 is located downstream of USP32 in GC, and USP32 could regulate the expression of SMAD2 and promote gastric carcinogenesis and cisplatin resistance by enhancing the stability of SMAD2 protein in gastric cancer cells, so targeting USP32 may be a potential therapeutic strategy for GC [25] (Fig. 6)."
37679322
reach
"Our laboratory previously reported that USP32 promotes tumorigenesis and chemoresistance in GC [8]."
37957631
eidos
"Furthermore , USP32 knockdown inhibited tumorigenesis in vivo ."
35440702
reach
"Furthermore, USP32 knockdown inhibited tumorigenesis in vivo."
35440702
NFE2L2 affects USP32
| 1 4
NFE2L2 binds USP32.
| 1 3
USP32 binds NFE2L2. 3 / 3
| 3
sparser
"Moreover, the Co-IP results indicated the direct association of USP32 with NRF2, suggesting that USP32 may be a deubiquitinase of NRF2."
40136417
sparser
"Taken together, these results revealed that LBT triggered ferroptosis in LUSC cells in vivo by targeting the USP32–NRF2 axis."
40136417
sparser
"Furthermore, the results of the Co-IP analysis also revealed a strong interaction between USP32 and NRF2 ( xref B)."
40136417
USP32 binds NFE2L2. 1 / 1
| 1
reach
"Furthermore, the results of the Co-IP analysis also revealed a strong interaction between USP32 and NRF2 (Figure 4B)."
40136417
NFE2L2 ubiquitinates USP32.
| 1
NFE2L2 ubiquitinates USP32. 1 / 1
| 1
sparser
"The results demonstrated that USP32 markedly inhibited Keap1-mediated NRF2 ubiquitination, whereas LBT treatment effectively reversed the deubiquitination of NRF2 mediated by USP32 ( xref D)."
40136417
Hsa_circ_0013880 affects USP32
| 4
Hsa_circ_0013880 activates USP32.
| 3
Hsa_circ_0013880 activates USP32. 3 / 3
| 3
reach
"Further in vitro cell experiments revealed that hsa_circ_0013880-mediated elevation of USP32 promoted cell proliferation and migration and reduced cell apoptosis."
36951484
reach
"Overexpression of hsa_circ_0013880 contributed to the growth of HL-60 cells by regulating USP32."
36951484
reach
"Consequently, we suggested that overexpression of hsa_circ_0013880 contributed to the survival of HL-60 cells by upregulating USP32."
36951484
Hsa_circ_0013880 increases the amount of USP32.
| 1
Hsa_circ_0013880 increases the amount of USP32. 1 / 1
| 1
reach
"Mechanistically, hsa_circ_0013880 could elevate the expression of USP32, a deubiquitinating enzyme that is highly expressed in the BMNCs of AML patients."
36951484
USP32 activates signal transduction. 4 / 4
| 4
reach
"These experimental results suggest that USP32 activates the RAF/MEK/ERK signaling pathway, which in turn promotes NSCLC cell proliferation, migration, and EMT progression through deubiquitination and stabilization of BAG3."
39030175
reach
"Additionally, USP32 promotes GC cell growth, metastasis, and chemoresistance by upregulating SMAD2, an important protein in the TGF-β signaling pathway [55]."
36497313
reach
"In summary, these findings support our theory that USP32 regulates the level of BAG3 protein to activate the RAF/MEK/ERK signaling pathway."
39030175
reach
"In conclusion, our study has found that USP32 promotes CRC development by activating the NF‐κB signalling pathway, and the USP32 –NF‐κB axis may act as a potential target for CRC therapy."
40122703
USP32 affects cell growth
| 1 3
USP32 activates cell growth.
| 1 2
USP32 activates cell growth. 3 / 3
| 1 2
reach
"The study of Dou et al. indicated that the high USP32 expression was significantly related to a high T stage and poor prognosis in gastric cancer, and USP32 could stabilize SMAD2 protein level to promote cell growth, motility, and chemoresistance to cisplatin [41]."
36582601
reach
"Additionally, USP32 promotes GC cell growth, metastasis, and chemoresistance by upregulating SMAD2, an important protein in the TGF-β signaling pathway [55]."
36497313
eidos
"USP32 downregulation inhibited cell growth and metastasis in vitro ."
35440702
USP32 inhibits cell growth.
| 1
USP32 inhibits cell growth. 1 / 1
| 1
reach
"USP32 downregulation inhibited cell growth and metastasis in vitro."
35440702
USP32 affects SMAD2
| 1 3
USP32 increases the amount of SMAD2.
| 2
USP32 increases the amount of SMAD2. 2 / 2
| 2
reach
"Mechanistically, USP32 silencing caused a decrease in the expression of SMAD2, which resulted in the inhibitory effects of GC cells on growth, motility, and chemoresistance to cisplatin."
32226309
reach
"The scientists discovered that USP32 modulates SMAD2 expression in a ubiquitin protease-dependent manner."
37679322
USP32 activates SMAD2.
| 1 1
USP32 activates SMAD2. 2 / 2
| 1 1
eidos
"Next , we provide evidence that knockdown of USP32 decreased the expression of SMAD2 ."
32226309
reach
"Additionally, USP32 promotes GC cell growth, metastasis, and chemoresistance by upregulating SMAD2, an important protein in the TGF-β signaling pathway [55]."
36497313
USP32 affects NFASC
| 4
USP32 activates NFASC. 4 / 4
| 4
reach
"In addition, IHC analysis of DLD1 and HCT116 xenograft tumours confirmed that USP32 could positively regulate the NF‐κB signalling pathway (Figure 7C)."
40122703
reach
"In conclusion, our study has found that USP32 promotes CRC development by activating the NF‐κB signalling pathway, and the USP32 –NF‐κB axis may act as a potential target for CRC therapy."
40122703
reach
"In the present study, we discovered that NF‐κB signalling is activated by USP32 overexpression and that the inhibition of the USP32–NF‐κB axis could reverse the proliferation, colony formation, anti‐apoptosis and migration abilities of CRC cells.To further verify USP32's oncogenic roles, we also performed in vivo studies."
40122703
reach
"Second, USP32 primarily performs biological functions by mediating the de‐ubiquitination process, and the mechanism of how USP32 activates NF‐κB expression remains unexplored.5 Conclusions."
40122703
USP32 affects LBT
| 4
USP32 binds LBT.
| 3
LBT binds USP32. 3 / 3
| 3
reach
"CETSA was further performed to validate the interaction between LBT and USP32."
40136417
reach
"As expected, the heat challenge quickly led to USP32 denaturation and precipitation, while LBT markedly increased the thermal stability of the USP32 protein at temperatures ranging from 42 °C to 54 °C (Figure 3F), confirming the direct binding of LBT to USP32."
40136417
reach
"Firstly, molecular docking and molecular dynamic simulations were conducted to estimate the interaction between LBT and USP32."
40136417
USP32 inhibits LBT.
| 1
USP32 inhibits LBT. 1 / 1
| 1
reach
"Importantly, USP32 overexpression effectively attenuated the effects of LBT on proliferation and ferroptosis in LUSC cells."
40136417
USP32 affects FDFT1
2 | 1 1
USP32 binds FDFT1.
2 | 1
FDFT1 binds USP32. 2 / 2
2 |
biogrid
No evidence text available
33961781
biogrid
No evidence text available
28514442
FDFT1 binds USP32. 1 / 1
| 1
sparser
"These results suggest that USP32-FDFT1 axis promotes the migration of epithelial ovarian cancer and may become a new target for EOC therapy [ xref ]."
37679322
USP32 activates FDFT1.
| 1
USP32 activates FDFT1. 1 / 1
| 1
reach
"FDFT1 was slightly downregulated by USP32 inhibition at the protein level ( Fig. 4 B), and strongly suppressed upon treatment with cycloheximide that inhibits protein synthesis ( Fig. 4 C), indicating[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
33744759
USP32 affects CRC
| 4
USP32 activates CRC.
| 2
USP32 activates CRC. 2 / 2
| 2
reach
"The above results show that USP32 promotes CRC progression via the activation of the NF‐κB signalling pathway.To verify the role of USP32 in the TME of CRC, we then constructed CT26–USP32 overexpressing cells (Figure S1A)."
40122703
reach
"In conclusion, our study has found that USP32 promotes CRC development by activating the NF‐κB signalling pathway, and the USP32 –NF‐κB axis may act as a potential target for CRC therapy."
40122703
USP32 inhibits CRC.
| 1
USP32 inhibits CRC. 1 / 1
| 1
reach
"We found that USP32 downregulation could suppress CRC tumour growth while overexpressing USP32 in CRC cells had the opposite function."
40122703
USP32 binds CRC.
| 1
USP32 binds CRC. 1 / 1
| 1
reach
"Of note, we also revealed the associations between USP32 and CRC's TME and found that the NF‐κB signalling pathway may be downstream of USP32.2 Materials and Methods."
40122703
Aflatoxin B1 affects USP32
3 |
Aflatoxin B1 methylates USP32.
2 |
Aflatoxin B1 methylates USP32. 2 / 2
2 |
ctd
No evidence text available
30157460
ctd
No evidence text available
27153756
Aflatoxin B1 increases the amount of USP32.
1 |
Aflatoxin B1 increases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
19770486
USP32 affects transport
| 3
USP32 activates transport.
| 2
USP32 activates transport. 2 / 2
| 2
reach
"Using proteome-wide ubiquitin remnant profiling, we reveal Rab7 to be a key substrate of USP32 and go on to show that USP32 supports Rab7 functions in transport and recycling from the MVB by two different mechanisms."
30926795
reach
"Secondly, USP32 supports the role of Rab7 in the transport and circulation of MVB through two different mechanisms [35]."
37679322
USP32 inhibits transport.
| 1
USP32 inhibits transport. 1 / 1
| 1
reach
"Loss of USP32 inhibits late endosome (LE) transport and recycling of LE cargos, resulting in dispersion and swelling of the late compartment."
30926795
USP32 affects cisplatin
| 3
USP32 activates cisplatin.
| 2
USP32 activates cisplatin. 2 / 2
| 2
reach
"These observations suggest that SMAD2 is located downstream of USP32 in GC, and USP32 could regulate the expression of SMAD2 and promote gastric carcinogenesis and cisplatin resistance by enhancing the stability of SMAD2 protein in gastric cancer cells, so targeting USP32 may be a potential therapeutic strategy for GC [25] (Fig. 6)."
37679322
reach
"Interestingly, a recent study also discovered that USP32 induces cisplatin resistance in GC cells [8]."
37957631
USP32 inhibits cisplatin.
| 1
USP32 inhibits cisplatin. 1 / 1
| 1
reach
"Gastric cancer cells’ cisplatin resistance can be decreased by down-regulating USP32 expression, indicating that USP32 is involved in the development of cisplatin resistance."
37679322
USP32 affects cell cycle
| 3
USP32 activates cell cycle. 3 / 3
| 3
reach
"Namely, we found that USP32 knockdown effectively inhibited HL-60 and U937 cell proliferation, arrested the cell cycle at G1 phase, and induced cell apoptosis."
36951484
reach
"Furthermore, USP32 silencing arrested cell cycle progression at G0/G1 phase via decreasing CDK4 and Cyclin D1 complex and elevating p21."
28597490
reach
"Moreover, USP32 was found to be overexpressed in human small cell lung cancer tissues, and USP32 silencing significantly suppressed small cell lung cancer cells proliferation and migration, cell cycle progression arrested and cell apoptosis (35)."
35116927
USP32 affects PKM2
| 3
USP32 binds PKM2. 3 / 3
| 3
sparser
"These findings confirm that USP32 directly interacts with PKM2 through its barrel domain."
41184228
sparser
"The regulatory mechanism underlying the interaction between USP32 and PKM2 was further investigated."
41184228
sparser
"The IP results indicated that USP32 specifically binds to PKM2’s barrel domain (aa 1-375) (Fig. xref )."
41184228
USP32 affects ORF3b
3 |
ORF3b binds USP32. 3 / 3
3 |
biogrid
No evidence text available
| DOI
biogrid
No evidence text available
| DOI
biogrid
No evidence text available
| DOI
USP32 affects CD274
| 3
USP32 binds CD274. 3 / 3
| 3
sparser
"Interaction studies showed that the N-terminal truncation U2 in USP32 binds with PD-L1, suggesting that DUSP domain of USP32 is critical for USP32-PD-L1 interaction (Figure xref G, lane 6, lower panel)."
41356798
sparser
"Binding studies showed that the PD-L1-ΔICD did not show any interaction with USP32, indicating that intracellular domain of PD-L1 contributes to the USP32-PD-L1 interaction (Figure xref H, lower panel)."
41356798
sparser
"Duolink proximity ligation assay (PLA) assay revealed that USP32 interacts with PD-L1, PLA dots appeared when both USP32 and PD-L1 antibodies were used (Figure xref E-F)."
41356798
USP32 affects 7b
3 |
7b binds USP32. 3 / 3
3 |
biogrid
No evidence text available
| DOI
biogrid
No evidence text available
| DOI
biogrid
No evidence text available
| DOI
PKM2 affects USP32
| 3
USP32 binds PKM2. 3 / 3
| 3
sparser
"These findings confirm that USP32 directly interacts with PKM2 through its barrel domain."
41184228
sparser
"The regulatory mechanism underlying the interaction between USP32 and PKM2 was further investigated."
41184228
sparser
"The IP results indicated that USP32 specifically binds to PKM2’s barrel domain (aa 1-375) (Fig. xref )."
41184228
ORF3b affects USP32
3 |
ORF3b binds USP32. 3 / 3
3 |
biogrid
No evidence text available
| DOI
biogrid
No evidence text available
| DOI
biogrid
No evidence text available
| DOI
MEIS1 affects USP32
3 |
MEIS1 decreases the amount of USP32. 3 / 3
3 |
biopax:msigdb
No evidence text available
biopax:msigdb
No evidence text available
biopax:msigdb
No evidence text available
FDFT1 affects USP32
2 | 1
FDFT1 binds USP32. 2 / 2
2 |
biogrid
No evidence text available
33961781
biogrid
No evidence text available
28514442
FDFT1 binds USP32. 1 / 1
| 1
sparser
"These results suggest that USP32-FDFT1 axis promotes the migration of epithelial ovarian cancer and may become a new target for EOC therapy [ xref ]."
37679322
CD274 affects USP32
| 3
USP32 binds CD274. 3 / 3
| 3
sparser
"Interaction studies showed that the N-terminal truncation U2 in USP32 binds with PD-L1, suggesting that DUSP domain of USP32 is critical for USP32-PD-L1 interaction (Figure xref G, lane 6, lower panel)."
41356798
sparser
"Binding studies showed that the PD-L1-ΔICD did not show any interaction with USP32, indicating that intracellular domain of PD-L1 contributes to the USP32-PD-L1 interaction (Figure xref H, lower panel)."
41356798
sparser
"Duolink proximity ligation assay (PLA) assay revealed that USP32 interacts with PD-L1, PLA dots appeared when both USP32 and PD-L1 antibodies were used (Figure xref E-F)."
41356798
7b affects USP32
3 |
7b binds USP32. 3 / 3
3 |
biogrid
No evidence text available
| DOI
biogrid
No evidence text available
| DOI
biogrid
No evidence text available
| DOI
2,3,7,8-tetrachlorodibenzodioxine decreases the amount of USP32.
2 |
2,3,7,8-tetrachlorodibenzodioxine decreases the amount of USP32. 2 / 2
2 |
ctd
No evidence text available
33387578
ctd
No evidence text available
21215274
2,3,7,8-tetrachlorodibenzodioxine increases the amount of USP32.
1 |
2,3,7,8-tetrachlorodibenzodioxine increases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
34747641
MiR-19b-3p affects USP32
| 2
MiR-19b-3p increases the amount of USP32.
| 1
MiR-19b-3p increases the amount of USP32. 1 / 1
| 1
reach
"Furthermore, by qRT-PCR, we detected these targeted genes and found that miR-19b-3p could up-regulate the expression of USP32 and RAB18 and down-regulated the expression of Dusp6, while there was no s[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
27138803
MiR-19b-3p decreases the amount of USP32.
| 1
Modified miR-19b-3p decreases the amount of USP32. 1 / 1
| 1
reach
"On the other hand, the over expression of miR-19b-3p was reported to repress the expression of USP32, RAB18 and Dusp6 involved in cell differentiation process and contribute to the inhibited proliferation and slow downed cycle of SH-SY5Y cells 35."
29330490
MiR-148a-3p affects USP32
| 2
MiR-148a-3p increases the amount of USP32.
| 1
MiR-148a-3p increases the amount of USP32. 1 / 1
| 1
reach
"These findings suggested that miR-148a-3p and miR-20a-5p mediated USP32 expression by targeting its 3′-UTR."
36951484
MiR-148a-3p decreases the amount of USP32.
| 1
MiR-148a-3p decreases the amount of USP32. 1 / 1
| 1
reach
"Real-time PCR assays showed that silencing of miR-148a-3p and miR-20a-5p could increase USP32 expression ( Figure 2D,E)."
36951484
Hsa-miR-93-5p affects USP32
2 |
Hsa-miR-93-5p decreases the amount of USP32. 2 / 2
2 |
biopax:mirtarbase
No evidence text available
22473208
biopax:mirtarbase
No evidence text available
23824327
Hsa-miR-519d-3p affects USP32
2 |
Hsa-miR-519d-3p decreases the amount of USP32. 2 / 2
2 |
biopax:mirtarbase
No evidence text available
23824327
biopax:mirtarbase
No evidence text available
22473208
Hsa-miR-20b-5p affects USP32
2 |
Hsa-miR-20b-5p decreases the amount of USP32. 2 / 2
2 |
biopax:mirtarbase
No evidence text available
23824327
biopax:mirtarbase
No evidence text available
22473208
Hsa-miR-20a-5p affects USP32
2 |
Hsa-miR-20a-5p decreases the amount of USP32. 2 / 2
2 |
biopax:mirtarbase
No evidence text available
23824327
biopax:mirtarbase
No evidence text available
22473208
Hsa-miR-17-5p affects USP32
2 |
Hsa-miR-17-5p decreases the amount of USP32. 2 / 2
2 |
biopax:mirtarbase
No evidence text available
23824327
biopax:mirtarbase
No evidence text available
22473208
Hsa-miR-106b-5p affects USP32
2 |
Hsa-miR-106b-5p decreases the amount of USP32. 2 / 2
2 |
biopax:mirtarbase
No evidence text available
22473208
biopax:mirtarbase
No evidence text available
23824327
ZDHHC17 affects USP32
2 |
ZDHHC17 binds USP32. 2 / 2
2 |
biogrid
No evidence text available
24705354
biogrid
No evidence text available
24705354
USP32 affects Ubiquitin
| 2
USP32 increases the amount of Ubiquitin.
| 1
USP32 increases the amount of Ubiquitin. 1 / 1
| 1
reach
"The 3’UTR location of USP32 mRNA was found to be the target of miR let-7a, and miR let-7a was able to reverse the reduction in ubiquitin levels caused by USP32."
37679322
USP32 activates Ubiquitin.
| 1
USP32 activates Ubiquitin. 1 / 1
| 1
reach
"USP32 has been reported to enhance the transmission of imatinib resistance by inhibiting the ubiquitin–proteasome system [40]."
40136417
USP32 affects USP32
| 2
USP32 decreases the amount of USP32.
| 1
USP32 decreases the amount of USP32. 1 / 1
| 1
reach
"Taken together, these results confirmed that miR let-7a can inhibit USP32 protein expression level by directly binding USP32 3'UTR.Our present results showed that USP32 expression is up-regulated in human BCa cells and miR let-7a significantly inhibits USP32 expression."
35116927
USP32 activates USP32.
| 1
USP32 activates USP32. 1 / 1
| 1
reach
"Therefore, revealing the regulatory mechanism of BAG3 will provide new perspectives for understanding the pathogenesis of NSCLC and new therapeutic strategies against NSCLC.According to the current investigation, there was an overexpression of USP32 in NSCLC, and this overexpression was linked to a poor prognosis."
39030175
USP32 affects UBC
2 |
UBC binds USP32. 2 / 2
2 |
biogrid
No evidence text available
28190767
biogrid
No evidence text available
29576527
USP32 affects TPCN2
2 |
TPCN2 binds USP32. 2 / 2
2 |
biogrid
No evidence text available
33961781
biogrid
No evidence text available
28514442
USP32 affects Stomach Neoplasms
| 2
USP32 activates Stomach Neoplasms. 2 / 2
| 2
reach
"Additionally, USP32 promotes GC cell growth, metastasis, and chemoresistance by upregulating SMAD2, an important protein in the TGF-β signaling pathway [55]."
36497313
reach
"Our laboratory previously reported that USP32 promotes tumorigenesis and chemoresistance in GC [8]."
37957631
reach
"Moreover, USP32 was found to be overexpressed in human small cell lung cancer tissues, and USP32 silencing significantly suppressed small cell lung cancer cells proliferation and migration, cell cycle progression arrested and cell apoptosis (35)."
35116927
reach
"Knockdown of USP32 significantly decreases the proliferation and migration rates of human small cell lung cancer [15]."
36951484
USP32 affects SMC1A
1 | 1
USP32 binds SMC1A. 2 / 2
1 | 1
biogrid
No evidence text available
19615732
reach
"Finally, RAD21 and USP32 are linked through a high-confidence Protein–Protein interaction between USP32 and SMC1A (SMC1A is part of the cohesin complex with RAD21)."
35906355
USP32 affects SLC31A1
2 |
SLC31A1 binds USP32. 2 / 2
2 |
biogrid
No evidence text available
40355756
biogrid
No evidence text available
33961781
USP32 affects SEMA4C
2 |
USP32 binds SEMA4C. 2 / 2
2 |
biogrid
No evidence text available
40819507
biogrid
No evidence text available
40819507
USP32 affects RRAS
| 2
USP32 activates RRAS. 2 / 2
| 2
reach
"Given the deubiquitination function of USP32, we further hypothesize that USP32 may mediate the malignant behaviors of AML cells by regulating the stability of Ras-related protein (Rap1b)."
36951484
reach
"Given the deubiquitination function of USP32, we then reasonably hypothesized that USP32 might contribute to the progression of AML by stabilizing Ras-related protein (Rap1b)."
36951484
USP32 affects RAB6B
2 |
RAB6B binds USP32. 2 / 2
2 |
biogrid
No evidence text available
28514442
biogrid
No evidence text available
33961781
USP32 affects Neoplasms
| 2
USP32 activates Neoplasms. 2 / 2
| 2
reach
"In vitro experiments confirm that USP32 promotes tumor growth."
37679322
reach
"10 Silencing of USP32 reduced cancer cell proliferation and migration in these studies and suggested USP32 as potential target for future therapy, although the tumor-promoting effects of USP32 are not[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
36476874
USP32 affects NSCLC
| 2
USP32 activates NSCLC. 2 / 2
| 2
reach
"Mechanistic investigations revealed that BAG3 is a substrate for USP32, and that USP32 directly interacts with BAG3 to promote NSCLC carcinogenesis through blocking BAG3 degradation."
39030175
reach
"USP32 promotes NSCLC cell proliferation and migration."
39030175
USP32 affects NME4
2 |
USP32 binds NME4. 2 / 2
2 |
biogrid
No evidence text available
28514442
biogrid
No evidence text available
33961781
USP32 affects N-calcineurin protein
| 2
USP32 increases the amount of N-calcineurin protein.
| 1
USP32 increases the amount of N-calcineurin protein. 1 / 1
| 1
reach
"The marker protein of epithelial–mesenchymal transformation (EMT) may be affected by the deletion of the USP32 gene, which can upregulate the expression of E-calcineurin and down-regulate the expression of N-calcineurin protein."
37679322
USP32 decreases the amount of N-calcineurin protein.
| 1
USP32 decreases the amount of N-calcineurin protein. 1 / 1
| 1
reach
"The marker protein of epithelial–mesenchymal transformation (EMT) may be affected by the deletion of the USP32 gene, which can upregulate the expression of E-calcineurin and down-regulate the expression of N-calcineurin protein."
37679322
USP32 affects MANSC1
2 |
MANSC1 binds USP32. 2 / 2
2 |
biogrid
No evidence text available
33961781
biogrid
No evidence text available
28514442
USP32 affects M
2 |
M binds USP32. 2 / 2
2 |
biogrid
No evidence text available
| DOI
biogrid
No evidence text available
| DOI
USP32 affects HYCC1
| 2
USP32 activates HYCC1. 2 / 2
| 2
reach
"Wet experiments confirmed that knockdown of USP32 could repress the proliferation, colony formation and migration of HCC cells in vitro and inhibit tumor growth in vivo."
37957631
reach
"These results indicate that USP32 may potentially regulate HCC development though regulating MAGE family members or being regulated by them."
37957631
USP32 affects ENTPD7
2 |
ENTPD7 binds USP32. 2 / 2
2 |
biogrid
No evidence text available
33961781
biogrid
No evidence text available
28514442
USP32 affects E
2 |
E binds USP32. 2 / 2
2 |
biogrid
No evidence text available
| DOI
biogrid
No evidence text available
38569033
USP32 affects CD83
2 |
CD83 binds USP32. 2 / 2
2 |
biogrid
No evidence text available
33961781
biogrid
No evidence text available
28514442
USP32 affects ALDH3B1
2 |
ALDH3B1 binds USP32. 2 / 2
2 |
biogrid
No evidence text available
28514442
biogrid
No evidence text available
33961781
USP32 affects 3a
2 |
3a binds USP32. 2 / 2
2 |
biogrid
No evidence text available
| DOI
biogrid
No evidence text available
| DOI
UBC affects USP32
2 |
UBC binds USP32. 2 / 2
2 |
biogrid
No evidence text available
28190767
biogrid
No evidence text available
29576527
TPCN2 affects USP32
2 |
TPCN2 binds USP32. 2 / 2
2 |
biogrid
No evidence text available
33961781
biogrid
No evidence text available
28514442
SMC1A affects USP32
1 | 1
USP32 binds SMC1A. 2 / 2
1 | 1
biogrid
No evidence text available
19615732
reach
"Finally, RAD21 and USP32 are linked through a high-confidence Protein–Protein interaction between USP32 and SMC1A (SMC1A is part of the cohesin complex with RAD21)."
35906355
SLC35F2 affects USP32
| 1 1
USP32 binds SLC35F2. 1 / 1
| 1
reach
"Researchers further found that the direct binding of USP32 and SLC35F2 in the endoplasmic reticulum could negatively regulate the stability of SLC35F2 and promote drug resistance to YM155 in breast cancer cells [32] (Fig. 6)."
37679322
USP32 binds SLC35F2. 1 / 1
| 1
sparser
"Researchers further found that the direct binding of USP32 and SLC35F2 in the endoplasmic reticulum could negatively regulate the stability of SLC35F2 and promote drug resistance to YM155 in breast cancer cells [ xref ] (Fig. xref )."
37679322
SLC31A1 affects USP32
2 |
SLC31A1 binds USP32. 2 / 2
2 |
biogrid
No evidence text available
40355756
biogrid
No evidence text available
33961781
SEMA4C affects USP32
2 |
USP32 binds SEMA4C. 2 / 2
2 |
biogrid
No evidence text available
40819507
biogrid
No evidence text available
40819507
RAB6B affects USP32
2 |
RAB6B binds USP32. 2 / 2
2 |
biogrid
No evidence text available
28514442
biogrid
No evidence text available
33961781
NME4 affects USP32
2 |
USP32 binds NME4. 2 / 2
2 |
biogrid
No evidence text available
28514442
biogrid
No evidence text available
33961781
MANSC1 affects USP32
2 |
MANSC1 binds USP32. 2 / 2
2 |
biogrid
No evidence text available
33961781
biogrid
No evidence text available
28514442
M affects USP32
2 |
M binds USP32. 2 / 2
2 |
biogrid
No evidence text available
| DOI
biogrid
No evidence text available
| DOI
ETV1 affects USP32
| 2
ETV1 increases the amount of USP32. 2 / 2
| 2
reach
"Additionally, we found that the transcription factor ETV1, which is a lineage survival factor in GISTs, promotes USP32 expression."
36725886
reach
"In gastrointestinal stromal tumors that are imatinib-resistant, ETV1 increases the expression of USP32."
37679322
ENTPD7 affects USP32
2 |
ENTPD7 binds USP32. 2 / 2
2 |
biogrid
No evidence text available
33961781
biogrid
No evidence text available
28514442
ELK1 affects USP32
2 |
ELK1 decreases the amount of USP32. 2 / 2
2 |
biopax:msigdb
No evidence text available
biopax:msigdb
No evidence text available
E affects USP32
2 |
E binds USP32. 2 / 2
2 |
biogrid
No evidence text available
| DOI
biogrid
No evidence text available
38569033
CD83 affects USP32
2 |
CD83 binds USP32. 2 / 2
2 |
biogrid
No evidence text available
33961781
biogrid
No evidence text available
28514442
ALDH3B1 affects USP32
2 |
ALDH3B1 binds USP32. 2 / 2
2 |
biogrid
No evidence text available
28514442
biogrid
No evidence text available
33961781
3a affects USP32
2 |
3a binds USP32. 2 / 2
2 |
biogrid
No evidence text available
| DOI
biogrid
No evidence text available
| DOI
Valproic acid affects USP32
1 |
Valproic acid demethylates USP32. 1 / 1
1 |
ctd
No evidence text available
29154799
Tungsten affects USP32
1 |
Tungsten decreases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
30912803
Tris(1,3-dichloro-2-propyl)phosphate decreases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
26743178
Triptonide affects USP32
1 |
Triptonide increases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
33045310
Topotecan affects USP32
1 |
Topotecan decreases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
25729387
Titanium dioxide affects USP32
1 |
Titanium dioxide demethylates USP32. 1 / 1
1 |
ctd
No evidence text available
35295148
Sodium arsenite affects USP32
1 |
Sodium arsenite increases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
38568856
SiUSP32-386 affects USP32
| 1
SiUSP32-386 inhibits USP32. 1 / 1
| 1
eidos
"Results Silencing of USP32 inhibits GC cell growth and migration in vitro USP32 expression was knocked down in MGC803 and SGC7901 cells by transient transfection with siRNAs against USP32 , and result of western blot analysis indicated that siUSP32-386 and siUSP32-3029 markedly decreased USP32 expression ( Figure 1A ) ."
32226309
SiUSP32-3029 affects USP32
| 1
SiUSP32-3029 inhibits USP32. 1 / 1
| 1
eidos
"Results Silencing of USP32 inhibits GC cell growth and migration in vitro USP32 expression was knocked down in MGC803 and SGC7901 cells by transient transfection with siRNAs against USP32 , and result of western blot analysis indicated that siUSP32-386 and siUSP32-3029 markedly decreased USP32 expression ( Figure 1A ) ."
32226309
Rotenone affects USP32
1 |
Rotenone decreases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
39786591
Resveratrol affects USP32
1 |
Resveratrol increases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
23557933
Progesterone affects USP32
1 |
Progesterone increases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
23012394
Potassium chromate decreases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
22079256
Pol-miR-363-3p affects USP32
| 1
Pol-miR-363-3p activates USP32. 1 / 1
| 1
reach
"In flounder, pol-miR-363-3p directly regulates USP32, and the expression levels of USP32 and pol-miR-363-3p correlate significantly with the extents of pathogen invasion."
32561457
Phorbol 13-acetate 12-myristate decreases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
25613284
Paracetamol affects USP32
1 |
Paracetamol decreases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
21420995
Oxaliplatin affects USP32
1 |
Oxaliplatin decreases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
25729387
MiR-20a-5p affects USP32
| 1
MiR-20a-5p decreases the amount of USP32. 1 / 1
| 1
reach
"Real-time PCR assays showed that silencing of miR-148a-3p and miR-20a-5p could increase USP32 expression ( Figure 2D,E)."
36951484
Methamphetamine affects USP32
1 |
Methamphetamine decreases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
29802913
Let-7a mimics affects USP32
| 1
Let-7a mimics decreases the amount of USP32. 1 / 1
| 1
reach
"The results indicated that let-7a mimics could reduce the protein level of USP32 (Figures 2B,S1A), while let-7a inhibitors enhanced the USP32 protein level (Figure 2C)."
35116927
Lead atom affects USP32
1 |
Lead atom increases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
19921347
Ionomycin affects USP32
1 |
Ionomycin decreases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
25613284
Hsa-mir-4696 affects USP32
1 |
Hsa-mir-4696 decreases the amount of USP32. 1 / 1
1 |
biopax:mirtarbase
No evidence text available
23824327
Hsa-mir-4295 affects USP32
1 |
Hsa-mir-4295 decreases the amount of USP32. 1 / 1
1 |
biopax:mirtarbase
No evidence text available
23824327
Hsa-mir-4273 affects USP32
1 |
Hsa-mir-4273 decreases the amount of USP32. 1 / 1
1 |
biopax:mirtarbase
No evidence text available
23824327
Hsa-mir-3666 affects USP32
1 |
Hsa-mir-3666 decreases the amount of USP32. 1 / 1
1 |
biopax:mirtarbase
No evidence text available
23824327
Hsa-mir-3609 affects USP32
1 |
Hsa-mir-3609 decreases the amount of USP32. 1 / 1
1 |
biopax:mirtarbase
No evidence text available
23824327
Hsa-mir-2117 affects USP32
1 |
Hsa-mir-2117 decreases the amount of USP32. 1 / 1
1 |
biopax:mirtarbase
No evidence text available
23824327
Hsa-miR-7156-5p affects USP32
1 |
Hsa-miR-7156-5p decreases the amount of USP32. 1 / 1
1 |
biopax:mirtarbase
No evidence text available
23824327
Hsa-miR-7110-3p affects USP32
1 |
Hsa-miR-7110-3p decreases the amount of USP32. 1 / 1
1 |
biopax:mirtarbase
No evidence text available
23824327
Hsa-miR-6873-3p affects USP32
1 |
Hsa-miR-6873-3p decreases the amount of USP32. 1 / 1
1 |
biopax:mirtarbase
No evidence text available
23824327
Hsa-miR-6833-3p affects USP32
1 |
Hsa-miR-6833-3p decreases the amount of USP32. 1 / 1
1 |
biopax:mirtarbase
No evidence text available
23824327
Hsa-miR-6817-3p affects USP32
1 |
Hsa-miR-6817-3p decreases the amount of USP32. 1 / 1
1 |
biopax:mirtarbase
No evidence text available
23824327
Hsa-miR-548ah-5p affects USP32
1 |
Hsa-miR-548ah-5p decreases the amount of USP32. 1 / 1
1 |
biopax:mirtarbase
No evidence text available
23824327
Hsa-miR-526b-3p affects USP32
1 |
Hsa-miR-526b-3p decreases the amount of USP32. 1 / 1
1 |
biopax:mirtarbase
No evidence text available
23824327
Hsa-miR-519c-3p affects USP32
1 |
Hsa-miR-519c-3p decreases the amount of USP32. 1 / 1
1 |
biopax:mirtarbase
No evidence text available
23824327
Hsa-miR-519b-3p affects USP32
1 |
Hsa-miR-519b-3p decreases the amount of USP32. 1 / 1
1 |
biopax:mirtarbase
No evidence text available
23824327
Hsa-miR-519a-3p affects USP32
1 |
Hsa-miR-519a-3p decreases the amount of USP32. 1 / 1
1 |
biopax:mirtarbase
No evidence text available
23824327
Hsa-miR-4796-3p affects USP32
1 |
Hsa-miR-4796-3p decreases the amount of USP32. 1 / 1
1 |
biopax:mirtarbase
No evidence text available
23824327
Hsa-miR-4768-5p affects USP32
1 |
Hsa-miR-4768-5p decreases the amount of USP32. 1 / 1
1 |
biopax:mirtarbase
No evidence text available
23824327
Hsa-miR-4753-3p affects USP32
1 |
Hsa-miR-4753-3p decreases the amount of USP32. 1 / 1
1 |
biopax:mirtarbase
No evidence text available
23824327
Hsa-miR-454-3p affects USP32
1 |
Hsa-miR-454-3p decreases the amount of USP32. 1 / 1
1 |
biopax:mirtarbase
No evidence text available
23824327
Hsa-miR-301b-3p affects USP32
1 |
Hsa-miR-301b-3p decreases the amount of USP32. 1 / 1
1 |
biopax:mirtarbase
No evidence text available
23824327
Hsa-miR-301a-3p affects USP32
1 |
Hsa-miR-301a-3p decreases the amount of USP32. 1 / 1
1 |
biopax:mirtarbase
No evidence text available
23824327
Hsa-miR-18a-3p affects USP32
1 |
Hsa-miR-18a-3p decreases the amount of USP32. 1 / 1
1 |
biopax:mirtarbase
No evidence text available
23622248
Hsa-miR-130b-5p affects USP32
1 |
Hsa-miR-130b-5p decreases the amount of USP32. 1 / 1
1 |
biopax:mirtarbase
No evidence text available
23824327
Hsa-miR-130b-3p affects USP32
1 |
Hsa-miR-130b-3p decreases the amount of USP32. 1 / 1
1 |
biopax:mirtarbase
No evidence text available
23824327
Hsa-miR-130a-3p affects USP32
1 |
Hsa-miR-130a-3p decreases the amount of USP32. 1 / 1
1 |
biopax:mirtarbase
No evidence text available
23824327
Hsa-miR-124-5p affects USP32
1 |
Hsa-miR-124-5p decreases the amount of USP32. 1 / 1
1 |
biopax:mirtarbase
No evidence text available
23824327
Hsa-miR-106a-5p affects USP32
1 |
Hsa-miR-106a-5p decreases the amount of USP32. 1 / 1
1 |
biopax:mirtarbase
No evidence text available
23824327
Hexabromocyclododecane decreases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
29177809
Gallic acid affects USP32
1 |
Gallic acid decreases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
34408198
Furan affects USP32
1 |
Furan methylates USP32. 1 / 1
1 |
ctd
No evidence text available
22079235
Fulvestrant affects USP32
1 |
Fulvestrant decreases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
16514628
Folic acid affects USP32
1 |
Folic acid increases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
22206623
Ferroptosis affects USP32
| 1
Ferroptosis activates USP32. 1 / 1
| 1
reach
"These results strongly confirmed that USP32-targeting contributes to LBT-induced ferroptosis in LUSC."
40136417
Dibutyl phthalate affects USP32
1 |
Dibutyl phthalate increases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
21266533
Cyclosporin A affects USP32
1 |
Cyclosporin A increases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
25562108
Cupric oxide affects USP32
1 |
Cupric oxide increases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
22077320
Coumarin affects USP32
1 |
Coumarin phosphorylates USP32. 1 / 1
1 |
ctd
No evidence text available
35688186
Copper(II) sulfate decreases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
19549813
Cisplatin affects USP32
1 |
Cisplatin decreases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
19561079
Chlorpyrifos affects USP32
1 |
Chlorpyrifos decreases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
37019170
Cadmium dichloride decreases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
24982889
Bta-miR-19b-3p affects USP32
| 1
Bta-miR-19b-3p decreases the amount of USP32. 1 / 1
| 1
reach
"Therefore, inhibited expression of USP32, RAB18 and Dusp6 caused by bta-miR-19b-3p may be conducive to the maintaining of undifferentiated SSCs in cattleyak, while downregulation of FOXO3 by bta-miR-592 could contribute to the transition of SSCs to a differentiating state, which was consistent with the conclusions from our previous study that spermatogenic arrest of cattleyak started at the stage of spermatogonial differentiation and get aggravated during meiosis 3."
29330490
Benzo[a]pyrene diol epoxide I decreases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
19150397
Aristolochic acid A decreases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
33212167
Amitrole affects USP32
1 |
Amitrole decreases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
38685447
Aluminium atom affects USP32
1 |
Aluminium atom decreases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
21298039
Afimoxifene affects USP32
1 |
Afimoxifene decreases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
16514628
ZEB1 affects USP32
1 |
ZEB1 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
37149635
YWHAB affects USP32
1 |
USP32 binds YWHAB. 1 / 1
1 |
biogrid
No evidence text available
19615732
XPO7 affects USP32
1 |
XPO7 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
36897256
WDR20 affects USP32
| 1
WDR20 activates USP32. 1 / 1
| 1
reach
"Neither was differentially methylated in our study, but several DMR genes mediate AR or its effects in various contexts in other species: hey2 (Fig. 1c), pkn1(102295574) and ncoa2, usp12, usp32 (Fig. 1b), and zmiz1(102310819) [84–88]."
31506062
VPS35 affects USP32
1 |
USP32 binds VPS35. 1 / 1
1 |
biogrid
No evidence text available
19615732
VIRMA affects USP32
1 |
VIRMA binds USP32. 1 / 1
1 |
biogrid
No evidence text available
29507755
VCPIP1 affects USP32
1 |
USP32 binds VCPIP1. 1 / 1
1 |
biogrid
No evidence text available
33961781
USP6 affects USP32
1 |
USP32 binds USP6. 1 / 1
1 |
biogrid
No evidence text available
19615732
USP4 affects USP32
1 |
USP4 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
19615732
USP32P2 affects USP32
1 |
USP32P2 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
19615732
USP32 affects v-ATPase
| 1
USP32 deubiquitinates v-ATPase. 1 / 1
| 1
reach
"In the presence of inactive USP32 (C743S) binding of LAMTOR1 to multiple v-ATPase subunits was significantly reduced, which suggests that USP32 needs to deubiquitinate LAMTOR1 for its efficient intera[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
36476874
USP32 affects tumorigenesis chemoresistance carcinoma
| 1
USP32 activates tumorigenesis chemoresistance carcinoma. 1 / 1
| 1
eidos
"USP32 promotes tumorigenesis and chemoresistance in gastric carcinoma via upregulation of SMAD2 USP32 , a member of the ubiquitin-specific proteases family , has been implicated in the development of breast cancer and small lung cancer ."
32226309
USP32 affects tmem161
| 1
USP32 activates tmem161. 1 / 1
| 1
reach
"In particular, TMEM167A, FAM46A, and USP32, which promote secretion upon knockdown, as well as C10orf88, WDR7, YPEL5, TMEM161, FAM162B, and GPR162, which inhibit secretion upon knockdown, deserve greater attention."
31488582
reach
"Recent studies have discovered that USP32 contributes to drug resistance in cancer: In several kinds of cancer cells, USP32 can confer cell resistance to a small molecule inhibitor YM155 (Sepantronium bromide) through promoting the degradation of SLC35F2, a solute-carrier protein that is essential for the uptake of YM155 [44]."
37957631
USP32 affects resistance GC cells cisplatin
| 1
USP32 activates resistance GC cells cisplatin. 1 / 1
| 1
eidos
"Furthermore , knockdown of USP32 attenuated the resistance of GC cells to cisplatin in CCK8 assays , whereas overexpression of SMAD2 partially rescued the defect of USP32 silenced GC cells in cisplatin resistance ( Figure 6B ) , suggesting that USP32 may confer chemoresistance in GC ."
32226309
reach
"USP32 knockdown increased apoptosis in addition to causing cell cycle arrest in the G0/G1 phase, with concomitant increases in Caspase3, cleaved PARP and P53-related apoptotic proteins."
37679322
USP32 affects process
| 1
USP32 activates process. 1 / 1
| 1
eidos
"Considering USP32 regulates SMAD2 expression , we attempted to elucidate whether USP32 could mediate this process ."
32226309
USP32 affects plasma membrane
| 1
USP32 inhibits plasma membrane. 1 / 1
| 1
reach
"In human cells, in addition to AMSH proteins , USP2 , USP6 , USP8/UBPY , USP9X , USP32 , and JosD1 have been shown to modulate the degradation of PM proteins."
36371501
USP32 affects pathway
| 1
USP32 activates pathway. 1 / 1
| 1
sparser
"Therefore, by deubiquitinating BAG3, we can show that USP32 can activate the RAF/MEK/ERK pathway."
39030175
USP32 affects mouse model
| 1
USP32 activates mouse model. 1 / 1
| 1
eidos
"Our data firstly demonstrate that USP32 downregulation significantly inhibited GC cell proliferation and migration in vitro , as well as in a mouse model ."
32226309
USP32 affects migration
| 1
USP32 activates migration. 1 / 1
| 1
eidos
"Our data firstly demonstrate that USP32 downregulation significantly inhibited GC cell proliferation and migration in vitro , as well as in a mouse model ."
32226309
USP32 affects migrated cells
| 1
USP32 activates migrated cells. 1 / 1
| 1
eidos
"Similarly , Transwell chamber assays also proved that knockdown of USP32 decreased the number of migrated cells while overexpression of SMAD2 compensated this phenotype ( Figure 5C ) ."
32226309
USP32 affects miR-19b-3p
| 1
USP32 activates miR-19b-3p. 1 / 1
| 1
reach
"To further determine if the changed expression of those genes resulted from the increased miRNAs, we carried out Western blot to validate and found that the results were consistent with qRT-PCR, sugge[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
27138803
USP32 affects metastatic foci lung surfaces
| 1
USP32 activates metastatic foci lung surfaces. 1 / 1
| 1
eidos
"Moreover , pulmonary metastasis assays were performed and the results showed that downregulation of USP32 markedly decreased metastatic foci on lung surfaces ( Figure 2B ) ."
32226309
USP32 affects lysosomal v-ATPase.Since
| 1
USP32 deubiquitinates lysosomal v-ATPase.Since. 1 / 1
| 1
reach
"In the presence of inactive USP32 (C743S) binding of LAMTOR1 to multiple v-ATPase subunits was significantly reduced, which suggests that USP32 needs to deubiquitinate LAMTOR1 for its efficient intera[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
36476874
USP32 affects localization
| 1
USP32 activates localization. 1 / 1
| 1
reach
"In turn, the DUB enzyme ubiquitin-specific protease 32 (USP32) removes the ubiquitin chains from Lys191, and then restores the late endosome motility and the perinuclear localization of the late compartment mediated by Rab7 (Sapmaz et al., 2019)."
34277632
USP32 affects growth migration defects investigate functional relevance USP32 SMAD2
| 1
USP32 inhibits growth migration defects investigate functional relevance USP32 SMAD2. 1 / 1
| 1
eidos
"SMAD2 restores USP32 knockdown induced growth and migration defects To investigate the functional relevance of USP32 and SMAD2 , we overexpressed SMAD2 together with knockdown of USP32 in MGC803 cells ( Figure 5A ) ."
32226309
USP32 affects fbxo5
| 1
USP32 increases the amount of fbxo5. 1 / 1
| 1
reach
"Interestingly, we also identified few genes where the knockdown promoted HRP secretion such as TMEM167A, FAM46A, as well as the ubiquitin specific peptidase USP32 (Fig. 3 A and Table S2)."
31488582
reach
"We carried out a number of rescue studies to look into the possibility that BAG3 is involved in USP32-mediated NSCLC cell proliferation, migration, and EMT."
39030175
reach
"USP32 promotes endosomal transport via the Rab7/RILP axis."
30926795
USP32 affects colony cells
| 1
USP32 inhibits colony cells. 1 / 1
| 1
eidos
"Consistently , downregulation of USP32 also led to an inhibitory effect on colony formation of those stable cells ( Figure 1C ) ."
32226309
USP32 affects cisplatin-resistance cells
| 1
USP32 activates cisplatin-resistance cells. 1 / 1
| 1
eidos
"In this regard , we also observed that USP32 downregulation could decrease the cisplatin-resistance in GC cells , suggesting the involvement of USP32 in drug resistance ."
32226309
USP32 affects autophagy
| 1
USP32 inhibits autophagy. 1 / 1
| 1
reach
"Our data show in addition that loss of USP32 induces autophagy."
36476874
USP32 affects ZEB1
1 |
ZEB1 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
37149635
USP32 affects YWHAB
1 |
USP32 binds YWHAB. 1 / 1
1 |
biogrid
No evidence text available
19615732
USP32 affects YPEL5
| 1
USP32 activates YPEL5. 1 / 1
| 1
reach
"In particular, TMEM167A, FAM46A, and USP32, which promote secretion upon knockdown, as well as C10orf88, WDR7, YPEL5, TMEM161, FAM162B, and GPR162, which inhibit secretion upon knockdown, deserve greater attention."
31488582
USP32 affects XPO7
1 |
XPO7 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
36897256
USP32 affects WDR7
| 1
USP32 activates WDR7. 1 / 1
| 1
reach
"In particular, TMEM167A, FAM46A, and USP32, which promote secretion upon knockdown, as well as C10orf88, WDR7, YPEL5, TMEM161, FAM162B, and GPR162, which inhibit secretion upon knockdown, deserve greater attention."
31488582
USP32 affects VPS35
1 |
USP32 binds VPS35. 1 / 1
1 |
biogrid
No evidence text available
19615732
USP32 affects VIRMA
1 |
VIRMA binds USP32. 1 / 1
1 |
biogrid
No evidence text available
29507755
USP32 affects VIM
| 1
USP32 inhibits VIM. 1 / 1
| 1
reach
"According to these findings, USP32 silencing A549 and H1299 cells exhibited increased E-cadherin and downregulated vimentin protein through Western blot analysis of molecular markers of epithelial and mesenchymal phenotypes (Fig. 2G)."
39030175
USP32 affects VCPIP1
1 |
USP32 binds VCPIP1. 1 / 1
1 |
biogrid
No evidence text available
33961781
USP32 affects Ubiquitination
| 1
eidos
"Loss of USP32 promotes ubiquitination within the unstructured N-terminal region of LAMTOR1 and prevents its efficient interaction with the vacuolar-type H + - ATPase , a prerequisite for full activation of MTORC1 at lysosomes ."
36847417
USP32 affects USP6
1 |
USP32 binds USP6. 1 / 1
1 |
biogrid
No evidence text available
19615732
USP32 affects USP4
1 |
USP4 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
19615732
USP32 affects USP32P2
1 |
USP32P2 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
19615732
USP32 affects USP15
1 |
USP15 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
28276505
USP32 affects UBXN6
1 |
USP32 binds UBXN6. 1 / 1
1 |
biogrid
No evidence text available
33961781
USP32 affects UBXN1
1 |
USP32 binds UBXN1. 1 / 1
1 |
biogrid
No evidence text available
19615732
USP32 affects TUBA1A
1 |
USP32 binds TUBA1A. 1 / 1
1 |
biogrid
No evidence text available
19615732
USP32 affects TTLL12
1 |
USP32 binds TTLL12. 1 / 1
1 |
biogrid
No evidence text available
33961781
USP32 affects TRIP13
1 |
USP32 binds TRIP13. 1 / 1
1 |
biogrid
No evidence text available
19615732
USP32 affects TRIP12
1 |
USP32 binds TRIP12. 1 / 1
1 |
biogrid
No evidence text available
33961781
USP32 affects TRIM74
1 |
USP32 binds TRIM74. 1 / 1
1 |
biogrid
No evidence text available
23105109
USP32 affects TRIM67
1 |
TRIM67 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
36215168
USP32 affects TRIM46
1 |
USP32 binds TRIM46. 1 / 1
1 |
biogrid
No evidence text available
23105109
USP32 affects TRIM3
1 |
TRIM3 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
32296183
USP32 affects TRIM25
1 |
TRIM25 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
29117863
USP32 affects TNIP2
1 |
TNIP2 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
27609421
USP32 affects TGOLN2
1 |
TGOLN2 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
29568061
USP32 affects TG
| 1
USP32 inhibits TG. 1 / 1
| 1
reach
"While in normal cells frequent transient interactions between these compartments were readily observed (Supplementary Movie 3 and 4), loss of USP32 caused TGN-derived membranes to remain stuck on enlarged acidified endosomes (Supplementary Movie 5, 6)."
30926795
USP32 affects TFEB
| 1
USP32 inhibits TFEB. 1 / 1
| 1
reach
"37 , 38 , 39 Knockdown of USP32 caused accumulation of TFEB in the nucleus as compared with cells transfected with non-targeting control siRNAs ( Figures 5 E and 5F), suggesting reduced mTORC1 activit[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
36476874
USP32 affects TAGLN
1 |
TAGLN binds USP32. 1 / 1
1 |
biogrid
No evidence text available
37149635
USP32 affects Smad2 Protein
| 1
USP32 activates Smad2 Protein. 1 / 1
| 1
eidos
"Results from western blots indicated that downregulation of USP32 dramatically decreased the SMAD2 protein level after protein synthesis was inhibited ( Figure 4E ) ."
32226309
USP32 affects SYNCRIP
1 |
SYNCRIP binds USP32. 1 / 1
1 |
biogrid
No evidence text available
26496610
USP32 affects SRC
1 |
USP32 binds SRC. 1 / 1
1 |
biogrid
No evidence text available
33961781
USP32 affects SORT1
1 |
SORT1 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
26496610
USP32 affects SNX3
1 |
USP32 binds SNX3. 1 / 1
1 |
biogrid
No evidence text available
33961781
USP32 affects SMAD4
| 1
SMAD4 binds USP32. 1 / 1
| 1
reach
"SMAD4 interacted with the deubiquitin ligases ubiquitin specific peptidase 9 X-linked (USP9X), ubiquitin specific peptidase 32 (USP32), and ubiquitin specific peptidase 7 (USP7) in the presence of both BRK-WT and BRK-YF."
31681835
USP32 affects SLC30A7
1 |
SLC30A7 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
40355756
USP32 affects SLC30A5
1 |
SLC30A5 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
40355756
USP32 affects SHMT2
| 1
USP32 increases the amount of SHMT2. 1 / 1
| 1
reach
"USP32 silencing diminishes the SHMT2 expression in the both initial and advanced stages of gastric cancer."
37210642
USP32 affects S
1 |
S binds USP32. 1 / 1
1 |
biogrid
No evidence text available
| DOI
USP32 affects RNF144A
1 |
USP32 binds RNF144A. 1 / 1
1 |
biogrid
No evidence text available
23105109
USP32 affects RIN1
1 |
USP32 binds RIN1. 1 / 1
1 |
biogrid
No evidence text available
33961781
USP32 affects RIGI
1 |
RIGI binds USP32. 1 / 1
1 |
biogrid
No evidence text available
32513696
USP32 affects RHOB
1 |
RHOB binds USP32. 1 / 1
1 |
biogrid
No evidence text available
34079125
USP32 affects RGL3
1 |
USP32 binds RGL3. 1 / 1
1 |
biogrid
No evidence text available
33961781
USP32 affects RELA
| 1
USP32 activates RELA. 1 / 1
| 1
reach
"As a result, we found that the knockdown of USP32 expression could decrease the protein expression levels of IKKα, IKKβ and p‐p65, while USP32 overexpression could increase the protein expression levels of IKKα, IKKβ and p‐p65, which was abrogated upon sc5741 treatment (Figure 5)."
40122703
USP32 affects RDH11
1 |
USP32 binds RDH11. 1 / 1
1 |
biogrid
No evidence text available
33961781
USP32 affects RBCK1
1 |
USP32 binds RBCK1. 1 / 1
1 |
biogrid
No evidence text available
23105109
USP32 affects RAB9A
1 |
RAB9A binds USP32. 1 / 1
1 |
biogrid
No evidence text available
34079125
USP32 affects RAB5A
| 1
USP32 deubiquitinates RAB5A. 1 / 1
| 1
reach
"In contrast to Rab7 (and in agreement with the proteomic analysis above), no deubiquitylation of GFP-Rab5 by USP32 was observed under the same reaction conditions (Fig. 4d; Supplementary Fig. 5e)."
30926795
USP32 affects RAB11A
1 |
RAB11A binds USP32. 1 / 1
1 |
biogrid
No evidence text available
34079125
USP32 affects Proteasome
| 1
USP32 activates Proteasome. 1 / 1
| 1
reach
"USP32 has been reported to enhance the transmission of imatinib resistance by inhibiting the ubiquitin–proteasome system [40]."
40136417
USP32 affects Pcna
1 |
Pcna binds USP32. 1 / 1
1 |
biogrid
No evidence text available
26496610
USP32 affects PTPN1
1 |
USP32 binds PTPN1. 1 / 1
1 |
biogrid
No evidence text available
33961781
USP32 affects PPP4R1L
1 |
PPP4R1L binds USP32. 1 / 1
1 |
biogrid
No evidence text available
33961781
USP32 affects PDXDC1
1 |
USP32 binds PDXDC1. 1 / 1
1 |
biogrid
No evidence text available
33961781
USP32 affects PARP1
| 1
USP32 activates PARP1. 1 / 1
| 1
reach
"In addition, downregulation of USP32 significantly induced cell apoptosis by activating cleaved caspase-3 and cleaved PARP, as well as inhibiting cell invasiveness via altering epithelial mesenchymal transition expression."
28597490
USP32 affects OXSR1
1 |
USP32 binds OXSR1. 1 / 1
1 |
biogrid
No evidence text available
33961781
USP32 inhibits Neoplasm Invasiveness. 1 / 1
| 1
reach
"In addition, downregulation of USP32 significantly induced cell apoptosis by activating cleaved caspase-3 and cleaved PARP, as well as inhibiting cell invasiveness via altering epithelial mesenchymal transition expression."
28597490
USP32 affects NRAS
1 |
NRAS binds USP32. 1 / 1
1 |
biogrid
No evidence text available
30639242
USP32 affects NIPAL1
1 |
NIPAL1 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
40355756
USP32 affects NFKB2
1 |
USP32 binds NFKB2. 1 / 1
1 |
biogrid
No evidence text available
33961781
USP32 affects NCK2
1 |
NCK2 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
32296183
USP32 affects NAB2
1 |
USP32 binds NAB2. 1 / 1
1 |
biogrid
No evidence text available
33961781
USP32 affects MicroRNAs
| 1
USP32 inhibits MicroRNAs. 1 / 1
| 1
reach
"However, overexpression of USP32 could reverse the effect of miR let-7a on MCF-7 cells proliferation."
35116927
USP32 affects MYC
1 |
MYC binds USP32. 1 / 1
1 |
biogrid
No evidence text available
35013218
USP32 affects MTNR1A
1 |
MTNR1A binds USP32. 1 / 1
1 |
biogrid
No evidence text available
26514267
USP32 affects MRPL39
1 |
USP32 binds MRPL39. 1 / 1
1 |
biogrid
No evidence text available
19615732
USP32 affects MID1IP1
1 |
MID1IP1 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
33961781
USP32 affects MEOX2
1 |
MEOX2 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
32296183
USP32 affects MAPRE2
1 |
USP32 binds MAPRE2. 1 / 1
1 |
biogrid
No evidence text available
33961781
USP32 affects MAPK8
1 |
USP32 binds MAPK8. 1 / 1
1 |
biogrid
No evidence text available
33961781
USP32 affects MAGE family
| 1
USP32 activates MAGE family. 1 / 1
| 1
reach
"These results indicate that USP32 may potentially regulate HCC development though regulating MAGE family members or being regulated by them."
37957631
USP32 activates Leukemia, Myeloid, Acute. 1 / 1
| 1
reach
"USP32 promotes the malignant behaviors of acute myeloid leukemia cells by regulating the stability of Rap1b [12]."
40136417
USP32 affects LRRC47
1 |
USP32 binds LRRC47. 1 / 1
1 |
biogrid
No evidence text available
19615732
USP32 affects LAMP3
1 |
LAMP3 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
34079125
USP32 affects LAMP2
1 |
LAMP2 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
34079125
USP32 affects LAMP1
1 |
LAMP1 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
29568061
USP32 affects KRT8
1 |
USP32 binds KRT8. 1 / 1
1 |
biogrid
No evidence text available
19615732
USP32 affects KRT19
1 |
USP32 binds KRT19. 1 / 1
1 |
biogrid
No evidence text available
19615732
USP32 affects KRT18
1 |
USP32 binds KRT18. 1 / 1
1 |
biogrid
No evidence text available
19615732
USP32 affects KRAS
1 |
KRAS binds USP32. 1 / 1
1 |
biogrid
No evidence text available
30639242
USP32 affects KCNE3
1 |
KCNE3 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
33961781
USP32 affects Infections
| 1
USP32 activates Infections. 1 / 1
| 1
reach
"Vivo research have shown that overexpression of USP32 and interfering with pol-miR-363-3p can increase Streptococcus dolphin infection in Paralichthys olivaceus tissue."
37679322
USP32 affects IKK_complex
| 1
USP32 increases the amount of IKK_complex. 1 / 1
| 1
reach
"As a result, we found that the knockdown of USP32 expression could decrease the protein expression levels of IKKα, IKKβ and p‐p65, while USP32 overexpression could increase the protein expression levels of IKKα, IKKβ and p‐p65, which was abrogated upon sc5741 treatment (Figure 5)."
40122703
USP32 affects IKBKG
1 |
USP32 binds IKBKG. 1 / 1
1 |
biogrid
No evidence text available
33961781
USP32 affects HSPA14
1 |
USP32 binds HSPA14. 1 / 1
1 |
biogrid
No evidence text available
33961781
USP32 affects HSPA12A
1 |
USP32 binds HSPA12A. 1 / 1
1 |
biogrid
No evidence text available
28514442
USP32 affects HRAS
1 |
HRAS binds USP32. 1 / 1
1 |
biogrid
No evidence text available
30639242
USP32 affects HDLBP
1 |
USP32 binds HDLBP. 1 / 1
1 |
biogrid
No evidence text available
33961781
USP32 affects HCC
| 1
USP32 binds HCC. 1 / 1
| 1
sparser
"USP32 shows high expression in hepatocellular carcinoma and is closely associated with HCC development and immunotherapy [ xref ]."
39030175
USP32 affects GTF2I
1 |
USP32 binds GTF2I. 1 / 1
1 |
biogrid
No evidence text available
33961781
USP32 affects GPR162
| 1
USP32 activates GPR162. 1 / 1
| 1
reach
"In particular, TMEM167A, FAM46A, and USP32, which promote secretion upon knockdown, as well as C10orf88, WDR7, YPEL5, TMEM161, FAM162B, and GPR162, which inhibit secretion upon knockdown, deserve greater attention."
31488582
USP32 affects GJD3
1 |
GJD3 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
34079125
USP32 affects GC cell
| 1
USP32 activates GC cell. 1 / 1
| 1
eidos
"Our data firstly demonstrate that USP32 downregulation significantly inhibited GC cell proliferation and migration in vitro , as well as in a mouse model ."
32226309
USP32 affects GAPVD1
1 |
USP32 binds GAPVD1. 1 / 1
1 |
biogrid
No evidence text available
33961781
USP32 affects Flag
| 1
USP32 binds Flag. 1 / 1
| 1
sparser
"After the H520 cells were transfected with Flag-USP32, the interacting proteins of USP32 were pulled down with FLAG-agarose for MS analysis."
40136417
USP32 affects FUT3
| 1
USP32 inhibits FUT3. 1 / 1
| 1
reach
"Loss of USP32 inhibits late endosome (LE) transport and recycling of LE cargos, resulting in dispersion and swelling of the late compartment."
30926795
USP32 affects FBXO32
1 |
FBXO32 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
33462405
USP32 affects FBXO22
1 |
FBXO22 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
36774506
USP32 affects FARSA
1 |
USP32 binds FARSA. 1 / 1
1 |
biogrid
No evidence text available
19615732
USP32 affects FAM162B
| 1
USP32 activates FAM162B. 1 / 1
| 1
reach
"In particular, TMEM167A, FAM46A, and USP32, which promote secretion upon knockdown, as well as C10orf88, WDR7, YPEL5, TMEM161, FAM162B, and GPR162, which inhibit secretion upon knockdown, deserve greater attention."
31488582
USP32 affects ESR2
1 |
ESR2 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
29509190
USP32 affects ERP44
1 |
USP32 binds ERP44. 1 / 1
1 |
biogrid
No evidence text available
19615732
USP32 affects EPHA7
1 |
EPHA7 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
35384245
USP32 affects EIF2AK2
1 |
USP32 binds EIF2AK2. 1 / 1
1 |
biogrid
No evidence text available
33961781
USP32 affects EFNB1
1 |
EFNB1 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
33961781
USP32 affects EEF1AKMT3
1 |
EEF1AKMT3 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
33961781
USP32 affects E-calcineurin
| 1
USP32 increases the amount of E-calcineurin. 1 / 1
| 1
reach
"The marker protein of epithelial–mesenchymal transformation (EMT) may be affected by the deletion of the USP32 gene, which can upregulate the expression of E-calcineurin and down-regulate the expression of N-calcineurin protein."
37679322
USP32 affects Disease
| 1
USP32 activates Disease. 1 / 1
| 1
reach
"Aberrant expression of USP32 triggers certain diseases such as Parkinson’s, Fragile X Syndrome, Chronic Kidney Disease and Cancer [11, 17–19]."
39030175
USP32 affects DYRK1A
1 |
DYRK1A binds USP32. 1 / 1
1 |
biogrid
No evidence text available
35914814
USP32 affects DVL2
1 |
USP32 binds DVL2. 1 / 1
1 |
biogrid
No evidence text available
33961781
USP32 affects DNAAF5
1 |
USP32 binds DNAAF5. 1 / 1
1 |
biogrid
No evidence text available
33961781
USP32 affects DNA Damage
| 1
USP32 inhibits DNA Damage. 1 / 1
| 1
reach
"Loss of USP32 enhances SLC35F2-mediated YM155-induced DNA damage and response [ 30 ]."
37801987
USP32 affects DIS3
1 |
USP32 binds DIS3. 1 / 1
1 |
biogrid
No evidence text available
33961781
USP32 affects DDX53
| 1
USP32 activates DDX53. 1 / 1
| 1
reach
"The results of in vivo studies showed that USP32 overexpression significantly promoted CT26 tumour progression (Figure S1B)."
40122703
USP32 affects Caspase
| 1
USP32 inhibits Caspase. 1 / 1
| 1
reach
"siRNA-mediated USP32 inhibition significantly increased caspase 3/7 activity ( Fig. S2A ) and the number of apoptotic cells in flow cytometry ( Fig. S2B )."
33744759
USP32 affects CX3CL1
1 |
CX3CL1 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
33961781
USP32 affects CUL3
1 |
CUL3 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
21145461
USP32 affects CRC Progression
| 1
USP32 activates CRC Progression. 1 / 1
| 1
reach
"These results indicate that USP32 may play a role in the TME of CRC.3.4 USP32 Promotes CRC Progression Both In Vitro and In Vivo."
40122703
USP32 affects COASY
1 |
USP32 binds COASY. 1 / 1
1 |
biogrid
No evidence text available
33961781
USP32 affects CHUK
1 |
USP32 binds CHUK. 1 / 1
1 |
biogrid
No evidence text available
33961781
USP32 affects CDK1
1 |
USP32 binds CDK1. 1 / 1
1 |
biogrid
No evidence text available
19615732
USP32 affects CDH1
| 1
USP32 decreases the amount of CDH1. 1 / 1
| 1
reach
"In the meantime, in H460 and H1299 cells, overexpression of USP32 dramatically enhanced the production of the protein vimentin and decreased the expression of the protein E-cadherin (Additional file 1: Fig. S1F, G)."
39030175
USP32 affects CASP3
| 1
USP32 activates CASP3. 1 / 1
| 1
reach
"In addition, downregulation of USP32 significantly induced cell apoptosis by activating cleaved caspase-3 and cleaved PARP, as well as inhibiting cell invasiveness via altering epithelial mesenchymal transition expression."
28597490
USP32 affects CAND1
1 |
CAND1 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
21145461
USP32 affects C3orf52
1 |
C3orf52 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
33961781
USP32 affects C10orf88
| 1
USP32 activates C10orf88. 1 / 1
| 1
reach
"In particular, TMEM167A, FAM46A, and USP32, which promote secretion upon knockdown, as well as C10orf88, WDR7, YPEL5, TMEM161, FAM162B, and GPR162, which inhibit secretion upon knockdown, deserve greater attention."
31488582
USP32 affects BAG6
1 |
BAG6 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
26496610
USP32 affects B3GAT1
1 |
B3GAT1 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
34079125
USP32 affects ATG9A
1 |
ATG9A binds USP32. 1 / 1
1 |
biogrid
No evidence text available
34369648
USP32 affects AQP9
1 |
AQP9 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
33961781
USP32 affects ANKRD29
1 |
ANKRD29 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
32296183
USP32 affects ANKHD1
1 |
USP32 binds ANKHD1. 1 / 1
1 |
biogrid
No evidence text available
33961781
USP32 affects ANKFY1
1 |
USP32 binds ANKFY1. 1 / 1
1 |
biogrid
No evidence text available
33961781
USP32 affects ABCF3
1 |
USP32 binds ABCF3. 1 / 1
1 |
biogrid
No evidence text available
33961781
USP32 affects ABCD3
1 |
USP32 binds ABCD3. 1 / 1
1 |
biogrid
No evidence text available
19615732
USP32 affects 7a
1 |
7a binds USP32. 1 / 1
1 |
biogrid
No evidence text available
| DOI
USP15 affects USP32
1 |
USP15 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
28276505
UBXN6 affects USP32
1 |
USP32 binds UBXN6. 1 / 1
1 |
biogrid
No evidence text available
33961781
UBXN1 affects USP32
1 |
USP32 binds UBXN1. 1 / 1
1 |
biogrid
No evidence text available
19615732
Tobacco Smoke Pollution increases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
33660061
TUBA1A affects USP32
1 |
USP32 binds TUBA1A. 1 / 1
1 |
biogrid
No evidence text available
19615732
TTLL12 affects USP32
1 |
USP32 binds TTLL12. 1 / 1
1 |
biogrid
No evidence text available
33961781
TRIP13 affects USP32
1 |
USP32 binds TRIP13. 1 / 1
1 |
biogrid
No evidence text available
19615732
TRIP12 affects USP32
1 |
USP32 binds TRIP12. 1 / 1
1 |
biogrid
No evidence text available
33961781
TRIM74 affects USP32
1 |
USP32 binds TRIM74. 1 / 1
1 |
biogrid
No evidence text available
23105109
TRIM67 affects USP32
1 |
TRIM67 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
36215168
TRIM46 affects USP32
1 |
USP32 binds TRIM46. 1 / 1
1 |
biogrid
No evidence text available
23105109
TRIM3 affects USP32
1 |
TRIM3 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
32296183
TRIM25 affects USP32
1 |
TRIM25 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
29117863
TNIP2 affects USP32
1 |
TNIP2 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
27609421
TGOLN2 affects USP32
1 |
TGOLN2 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
29568061
TCF3 affects USP32
1 |
TCF3 decreases the amount of USP32. 1 / 1
1 |
biopax:msigdb
No evidence text available
TAGLN affects USP32
1 |
TAGLN binds USP32. 1 / 1
1 |
biogrid
No evidence text available
37149635
SYNCRIP affects USP32
1 |
SYNCRIP binds USP32. 1 / 1
1 |
biogrid
No evidence text available
26496610
SRY affects USP32
1 |
SRY decreases the amount of USP32. 1 / 1
1 |
biopax:msigdb
No evidence text available
SRC affects USP32
1 |
USP32 binds SRC. 1 / 1
1 |
biogrid
No evidence text available
33961781
SP1 affects USP32
1 |
SP1 decreases the amount of USP32. 1 / 1
1 |
biopax:msigdb
No evidence text available
SOX5 affects USP32
1 |
SOX5 decreases the amount of USP32. 1 / 1
1 |
biopax:msigdb
No evidence text available
SORT1 affects USP32
1 |
SORT1 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
26496610
SNX3 affects USP32
1 |
USP32 binds SNX3. 1 / 1
1 |
biogrid
No evidence text available
33961781
SMAD4 affects USP32
| 1
SMAD4 binds USP32. 1 / 1
| 1
reach
"SMAD4 interacted with the deubiquitin ligases ubiquitin specific peptidase 9 X-linked (USP9X), ubiquitin specific peptidase 32 (USP32), and ubiquitin specific peptidase 7 (USP7) in the presence of both BRK-WT and BRK-YF."
31681835
SMAD2 affects USP32
| 1
SMAD2 inhibits USP32. 1 / 1
| 1
reach
"Meanwhile, rescue experiments showed that overexpression of SMAD2 could reverse the effects of silenced USP32 on gastric cancer cell growth, metastasis and cisplatin resistance."
37679322
SLC30A7 affects USP32
1 |
SLC30A7 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
40355756
SLC30A5 affects USP32
1 |
SLC30A5 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
40355756
S affects USP32
1 |
S binds USP32. 1 / 1
1 |
biogrid
No evidence text available
| DOI
Raloxifene Hydrochloride decreases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
16514628
RREB1 affects USP32
1 |
RREB1 decreases the amount of USP32. 1 / 1
1 |
biopax:msigdb
No evidence text available
RNF144A affects USP32
1 |
USP32 binds RNF144A. 1 / 1
1 |
biogrid
No evidence text available
23105109
RIN1 affects USP32
1 |
USP32 binds RIN1. 1 / 1
1 |
biogrid
No evidence text available
33961781
RIGI affects USP32
1 |
RIGI binds USP32. 1 / 1
1 |
biogrid
No evidence text available
32513696
RHOB affects USP32
1 |
RHOB binds USP32. 1 / 1
1 |
biogrid
No evidence text available
34079125
RGL3 affects USP32
1 |
USP32 binds RGL3. 1 / 1
1 |
biogrid
No evidence text available
33961781
REPIN1 affects USP32
1 |
REPIN1 decreases the amount of USP32. 1 / 1
1 |
biopax:msigdb
No evidence text available
RDH11 affects USP32
1 |
USP32 binds RDH11. 1 / 1
1 |
biogrid
No evidence text available
33961781
RBCK1 affects USP32
1 |
USP32 binds RBCK1. 1 / 1
1 |
biogrid
No evidence text available
23105109
RAB9A affects USP32
1 |
RAB9A binds USP32. 1 / 1
1 |
biogrid
No evidence text available
34079125
RAB7A affects USP32
1 |
RAB7A binds USP32. 1 / 1
1 |
biogrid
No evidence text available
34432599
RAB11A affects USP32
1 |
RAB11A binds USP32. 1 / 1
1 |
biogrid
No evidence text available
34079125
Poly I-C affects USP32
1 |
Poly I-C decreases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
26923065
Plant Extracts affects USP32
1 |
Plant Extracts increases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
23557933
Pcna affects USP32
1 |
Pcna binds USP32. 1 / 1
1 |
biogrid
No evidence text available
26496610
PTPN1 affects USP32
1 |
USP32 binds PTPN1. 1 / 1
1 |
biogrid
No evidence text available
33961781
PPP4R1L affects USP32
1 |
PPP4R1L binds USP32. 1 / 1
1 |
biogrid
No evidence text available
33961781
POU3F2 affects USP32
1 |
POU3F2 decreases the amount of USP32. 1 / 1
1 |
biopax:msigdb
No evidence text available
PDXDC1 affects USP32
1 |
USP32 binds PDXDC1. 1 / 1
1 |
biogrid
No evidence text available
33961781
PAX4 affects USP32
1 |
PAX4 decreases the amount of USP32. 1 / 1
1 |
biopax:msigdb
No evidence text available
OXSR1 affects USP32
1 |
USP32 binds OXSR1. 1 / 1
1 |
biogrid
No evidence text available
33961781
Neoplasms affects USP32
| 1
Neoplasms inhibits USP32. 1 / 1
| 1
reach
"A peritoneal tumor’s ability to metastasize can be prevented by inhibiting USP32."
37679322
NRAS affects USP32
1 |
NRAS binds USP32. 1 / 1
1 |
biogrid
No evidence text available
30639242
NIPAL1 affects USP32
1 |
NIPAL1 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
40355756
NFKB2 affects USP32
1 |
USP32 binds NFKB2. 1 / 1
1 |
biogrid
No evidence text available
33961781
NCK2 affects USP32
1 |
NCK2 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
32296183
NAB2 affects USP32
1 |
USP32 binds NAB2. 1 / 1
1 |
biogrid
No evidence text available
33961781
MicroRNA let-7a affects USP32
| 1
MicroRNA let-7a decreases the amount of USP32. 1 / 1
| 1
reach
"MicroRNA let-7a inhibits proliferation of breast cancer cell by downregulating USP32 expression."
35116927
MYC affects USP32
1 |
MYC binds USP32. 1 / 1
1 |
biogrid
No evidence text available
35013218
MYB affects USP32
1 |
MYB decreases the amount of USP32. 1 / 1
1 |
biopax:msigdb
No evidence text available
MTNR1A affects USP32
1 |
MTNR1A binds USP32. 1 / 1
1 |
biogrid
No evidence text available
26514267
MRPL39 affects USP32
1 |
USP32 binds MRPL39. 1 / 1
1 |
biogrid
No evidence text available
19615732
MID1IP1 affects USP32
1 |
MID1IP1 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
33961781
MEOX2 affects USP32
1 |
MEOX2 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
32296183
MARCHF8 affects USP32
| 1
MARCHF8 decreases the amount of USP32. 1 / 1
| 1
reach
"MiR let-7a downregulates USP32 protein expression in MCF-7 cells."
35116927
MAPRE2 affects USP32
1 |
USP32 binds MAPRE2. 1 / 1
1 |
biogrid
No evidence text available
33961781
MAPK8 affects USP32
1 |
USP32 binds MAPK8. 1 / 1
1 |
biogrid
No evidence text available
33961781
MAGEC2 affects USP32
| 1
MAGEC2 activates USP32. 1 / 1
| 1
reach
"Further research is required to determine whether USP32 is a specific biomarker for Asian HCC patients.To explore potential molecular mechanisms by which USP32 regulates HCC progression, we conducted several analyses and identified key USP32-related molecular modules, including MAGEA3, MAGEC1, MAGEC2 and MAGEA1."
37957631
MAGEC1 affects USP32
| 1
MAGEC1 activates USP32. 1 / 1
| 1
reach
"Further research is required to determine whether USP32 is a specific biomarker for Asian HCC patients.To explore potential molecular mechanisms by which USP32 regulates HCC progression, we conducted several analyses and identified key USP32-related molecular modules, including MAGEA3, MAGEC1, MAGEC2 and MAGEA1."
37957631
MAGEA3 affects USP32
| 1
MAGEA3 activates USP32. 1 / 1
| 1
reach
"Further research is required to determine whether USP32 is a specific biomarker for Asian HCC patients.To explore potential molecular mechanisms by which USP32 regulates HCC progression, we conducted several analyses and identified key USP32-related molecular modules, including MAGEA3, MAGEC1, MAGEC2 and MAGEA1."
37957631
MAGEA1 affects USP32
| 1
MAGEA1 activates USP32. 1 / 1
| 1
reach
"Further research is required to determine whether USP32 is a specific biomarker for Asian HCC patients.To explore potential molecular mechanisms by which USP32 regulates HCC progression, we conducted several analyses and identified key USP32-related molecular modules, including MAGEA3, MAGEC1, MAGEC2 and MAGEA1."
37957631
LRRC47 affects USP32
1 |
USP32 binds LRRC47. 1 / 1
1 |
biogrid
No evidence text available
19615732
LEF1 affects USP32
1 |
LEF1 decreases the amount of USP32. 1 / 1
1 |
biopax:msigdb
No evidence text available
LAMTOR1 affects USP32
1 |
LAMTOR1 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
34079125
LAMP3 affects USP32
1 |
LAMP3 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
34079125
LAMP2 affects USP32
1 |
LAMP2 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
34079125
LAMP1 affects USP32
1 |
LAMP1 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
29568061
KRT8 affects USP32
1 |
USP32 binds KRT8. 1 / 1
1 |
biogrid
No evidence text available
19615732
KRT19 affects USP32
1 |
USP32 binds KRT19. 1 / 1
1 |
biogrid
No evidence text available
19615732
KRT18 affects USP32
1 |
USP32 binds KRT18. 1 / 1
1 |
biogrid
No evidence text available
19615732
KRAS affects USP32
1 |
KRAS binds USP32. 1 / 1
1 |
biogrid
No evidence text available
30639242
KCNE3 affects USP32
1 |
KCNE3 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
33961781
IRF1 affects USP32
1 |
IRF1 decreases the amount of USP32. 1 / 1
1 |
biopax:msigdb
No evidence text available
IKBKG affects USP32
1 |
USP32 binds IKBKG. 1 / 1
1 |
biogrid
No evidence text available
33961781
Hsa_circ_0013880 affects USP32
| 1
Hsa_circ_0013880 activates USP32. 1 / 1
| 1
reach
"Hsa_circ_0013880 overexpression can either positively regulate USP32 protein and increase AML cell proliferation."
37679322
HU 211 affects USP32
1 |
HU 211 decreases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
26923065
HSPA14 affects USP32
1 |
USP32 binds HSPA14. 1 / 1
1 |
biogrid
No evidence text available
33961781
HSPA12A affects USP32
1 |
USP32 binds HSPA12A. 1 / 1
1 |
biogrid
No evidence text available
28514442
HRAS affects USP32
1 |
HRAS binds USP32. 1 / 1
1 |
biogrid
No evidence text available
30639242
HOXA9 affects USP32
1 |
HOXA9 decreases the amount of USP32. 1 / 1
1 |
biopax:msigdb
No evidence text available
HDLBP affects USP32
1 |
USP32 binds HDLBP. 1 / 1
1 |
biogrid
No evidence text available
33961781
HCC affects USP32
| 1
USP32 binds HCC. 1 / 1
| 1
sparser
"USP32 shows high expression in hepatocellular carcinoma and is closely associated with HCC development and immunotherapy [ xref ]."
39030175
GTF2I affects USP32
1 |
USP32 binds GTF2I. 1 / 1
1 |
biogrid
No evidence text available
33961781
GJD3 affects USP32
1 |
GJD3 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
34079125
GAPVD1 affects USP32
1 |
USP32 binds GAPVD1. 1 / 1
1 |
biogrid
No evidence text available
33961781
Flag affects USP32
| 1
USP32 binds Flag. 1 / 1
| 1
sparser
"After the H520 cells were transfected with Flag-USP32, the interacting proteins of USP32 were pulled down with FLAG-agarose for MS analysis."
40136417
FDFT1 inhibitor affects USP32
| 1
FDFT1 inhibitor inhibits USP32. 1 / 1
| 1
reach
"They showed that USP32 and FDFT1 expression was higher in tumor spheroids than in adnexal cells, and that the FDFT1 inhibitor ZA, blocking USP32, or interfering with the mevalonate pathway might inhibit the formation of tumor spheres in epithelial ovarian cancer (Fig. 6)."
37679322
FBXO32 affects USP32
1 |
FBXO32 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
33462405
FBXO22 affects USP32
1 |
FBXO22 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
36774506
FARSA affects USP32
1 |
USP32 binds FARSA. 1 / 1
1 |
biogrid
No evidence text available
19615732
ESR2 affects USP32
1 |
ESR2 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
29509190
ERP44 affects USP32
1 |
USP32 binds ERP44. 1 / 1
1 |
biogrid
No evidence text available
19615732
EPHA7 affects USP32
1 |
EPHA7 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
35384245
EIF2AK2 affects USP32
1 |
USP32 binds EIF2AK2. 1 / 1
1 |
biogrid
No evidence text available
33961781
EFNB1 affects USP32
1 |
EFNB1 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
33961781
EEF1AKMT3 affects USP32
1 |
EEF1AKMT3 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
33961781
DYRK1A affects USP32
1 |
DYRK1A binds USP32. 1 / 1
1 |
biogrid
No evidence text available
35914814
DVL2 affects USP32
1 |
USP32 binds DVL2. 1 / 1
1 |
biogrid
No evidence text available
33961781
DNAAF5 affects USP32
1 |
USP32 binds DNAAF5. 1 / 1
1 |
biogrid
No evidence text available
33961781
DIS3 affects USP32
1 |
USP32 binds DIS3. 1 / 1
1 |
biogrid
No evidence text available
33961781
reach
"They showed that USP32 and FDFT1 expression was higher in tumor spheroids than in adnexal cells, and that the FDFT1 inhibitor ZA, blocking USP32, or interfering with the mevalonate pathway might inhibit the formation of tumor spheres in epithelial ovarian cancer (Fig. 6)."
37679322
CX3CL1 affects USP32
1 |
CX3CL1 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
33961781
CUL3 affects USP32
1 |
CUL3 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
21145461
CRC affects USP32
| 1
USP32 binds CRC. 1 / 1
| 1
reach
"Of note, we also revealed the associations between USP32 and CRC's TME and found that the NF‐κB signalling pathway may be downstream of USP32.2 Materials and Methods."
40122703
COASY affects USP32
1 |
USP32 binds COASY. 1 / 1
1 |
biogrid
No evidence text available
33961781
CHUK affects USP32
1 |
USP32 binds CHUK. 1 / 1
1 |
biogrid
No evidence text available
33961781
CEBPA affects USP32
1 |
CEBPA decreases the amount of USP32. 1 / 1
1 |
biopax:msigdb
No evidence text available
CDK1 affects USP32
1 |
USP32 binds CDK1. 1 / 1
1 |
biogrid
No evidence text available
19615732
CAND1 affects USP32
1 |
CAND1 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
21145461
C60 fullerene affects USP32
1 |
C60 fullerene increases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
19167457
C3orf52 affects USP32
1 |
C3orf52 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
33961781
BEP protocol affects USP32
1 |
BEP protocol decreases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
18987330
BAG6 affects USP32
1 |
BAG6 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
26496610
B3GAT1 affects USP32
1 |
B3GAT1 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
34079125
Acrylamide affects USP32
1 |
Acrylamide decreases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
28959563
ATG9A affects USP32
1 |
ATG9A binds USP32. 1 / 1
1 |
biogrid
No evidence text available
34369648
AQP9 affects USP32
1 |
AQP9 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
33961781
ANKRD29 affects USP32
1 |
ANKRD29 binds USP32. 1 / 1
1 |
biogrid
No evidence text available
32296183
ANKHD1 affects USP32
1 |
USP32 binds ANKHD1. 1 / 1
1 |
biogrid
No evidence text available
33961781
ANKFY1 affects USP32
1 |
USP32 binds ANKFY1. 1 / 1
1 |
biogrid
No evidence text available
33961781
ABCF3 affects USP32
1 |
USP32 binds ABCF3. 1 / 1
1 |
biogrid
No evidence text available
33961781
ABCD3 affects USP32
1 |
USP32 binds ABCD3. 1 / 1
1 |
biogrid
No evidence text available
19615732
7a affects USP32
1 |
7a binds USP32. 1 / 1
1 |
biogrid
No evidence text available
| DOI
ctd
No evidence text available
35124124
ctd
No evidence text available
39786591
2-hydroxypropanoic acid decreases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
30851411
17beta-estradiol affects USP32
1 |
17beta-estradiol increases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
16514628
1,3-dinitrobenzene increases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
24140754
1,2-dimethylhydrazine decreases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
22206623
(-)-epigallocatechin 3-gallate decreases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
22079256
4,4'-sulfonyldiphenol decreases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
39298647
2,3',4,4',5-pentachlorobiphenyl increases the amount of USP32. 1 / 1
1 |
ctd
No evidence text available
31388691