IndraLab

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USP32 activates cell growth. 3 / 3
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"The study of Dou et al. indicated that the high USP32 expression was significantly related to a high T stage and poor prognosis in gastric cancer, and USP32 could stabilize SMAD2 protein level to promote cell growth, motility, and chemoresistance to cisplatin [41]."
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"Additionally, USP32 promotes GC cell growth, metastasis, and chemoresistance by upregulating SMAD2, an important protein in the TGF-β signaling pathway [55]."
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"USP32 downregulation inhibited cell growth and metastasis in vitro ."
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