IndraLab

Statements

USP32 activates RAB7A. 4 / 4
| 4
reach
"Taken together, our data indicated that Rab7 function can be modulated by USP32-sensitive ubiquitination and that USP32 deficiency resulted in altered retromer-mediated trafficking and autophagy induc[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
36476874
reach
"Indeed, USP32 depletion sequesters Rab7 in abnormally enlarged endosomal structures, and the accumulation of ubiquitinylated Rab7 promotes interactions with the retromer and inhibits interactions with RILP [29]."
32033485
reach
"Using proteome-wide ubiquitin remnant profiling, we reveal Rab7 to be a key substrate of USP32 and go on to show that USP32 supports Rab7 functions in transport and recycling from the MVB by two different mechanisms."
30926795
reach
"Secondly, USP32 supports the role of Rab7 in the transport and circulation of MVB through two different mechanisms [35]."
37679322