IndraLab

Statements


USP32 activates RAP1B. 5 / 5
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"Given the deubiquitination function of USP32, we further hypothesize that USP32 may mediate the malignant behaviors of AML cells by regulating the stability of Ras-related protein (Rap1b)."

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"Given the deubiquitination function of USP32, we then reasonably hypothesized that USP32 might contribute to the progression of AML by stabilizing Ras-related protein (Rap1b)."

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"Knockdown of USP32 reduced the stability of the Rap1b protein ."

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"Accordingly, we demonstrated that knockdown of USP32 could reduce the stability of the Rap1b protein."

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"USP32 promotes the malignant behaviors of acute myeloid leukemia cells by regulating the stability of Rap1b [12]."