IndraLab

Statements

USP32 activates cell cycle. 3 / 3
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"Furthermore, USP32 silencing arrested cell cycle progression at G0/G1 phase via decreasing CDK4 and Cyclin D1 complex and elevating p21."
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"Namely, we found that USP32 knockdown effectively inhibited HL-60 and U937 cell proliferation, arrested the cell cycle at G1 phase, and induced cell apoptosis."
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"Moreover, USP32 was found to be overexpressed in human small cell lung cancer tissues, and USP32 silencing significantly suppressed small cell lung cancer cells proliferation and migration, cell cycle progression arrested and cell apoptosis (35)."
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