IndraLab

Statements


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reach
"Mechanistic investigations revealed that BAG3 is a substrate for USP32, and that USP32 directly interacts with BAG3 to promote NSCLC carcinogenesis through blocking BAG3 degradation."

reach
"These observations suggest that SMAD2 is located downstream of USP32 in GC, and USP32 could regulate the expression of SMAD2 and promote gastric carcinogenesis and cisplatin resistance by enhancing the stability of SMAD2 protein in gastric cancer cells, so targeting USP32 may be a potential therapeutic strategy for GC [25] (Fig. 6)."

reach
"Our laboratory previously reported that USP32 promotes tumorigenesis and chemoresistance in GC [8]."

eidos
"Furthermore , USP32 knockdown inhibited tumorigenesis in vivo ."

reach
"Furthermore, USP32 knockdown inhibited tumorigenesis in vivo."