IndraLab

Statements

USP32 activates apoptotic process. 3 / 3
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"Namely, we found that USP32 knockdown effectively inhibited HL-60 and U937 cell proliferation, arrested the cell cycle at G1 phase, and induced cell apoptosis."
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"In addition, downregulation of USP32 significantly induced cell apoptosis by activating cleaved caspase-3 and cleaved PARP, as well as inhibiting cell invasiveness via altering epithelial mesenchymal transition expression."
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"Moreover, USP32 was found to be overexpressed in human small cell lung cancer tissues, and USP32 silencing significantly suppressed small cell lung cancer cells proliferation and migration, cell cycle progression arrested and cell apoptosis (35)."
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