IndraLab

Statements


PSMD7 affects PSMD14
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"Here we describe a method for the purification of the Rpn8/Rpn11 heterodimer and ubiquitin-GC-TAMRA, a model substrate that can be used to characterize the DUB activity of Rpn11 in isolation without the need of purifying 26S proteasomes."

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"After transferring Zn ion to the Rpn11, we used both the Rpn11 monomer (Figure 2A) and the Rpn8-Rpn11 heterodimer (Figure 3A) structures for subsequent analysis.For the CSN5 monomer (Figure 2B), the recently solved crystal structure of CSN5 with CSN5i-3 (PDB_code: 5JOG) (Schlierf et al., 2016) was considered."

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"In the Rpn8-Rpn11 heterodimer, capzimin showed a bidentate coordination with Zn and a stable H-bond with side chain of Thr129 (Figure S4B)."

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"This feature opens the possibility that the regulatory particle, free lid subcomplex or the heterodimer PSMD14-PSMD7 might play other physiological roles including a positive function on protein stability through deubiquitination."

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"Thus, we investigated whether this was an unrealistic over binding, a protein-protein complex environment would be able to reproduce the selectivity.In the heterodimeric Rpn8-Rpn11 complex, CSN5i-3 binding in the pocket was not stable (Figure 7C), the distance to zinc increases continously and eventually the ligand lost coordination with Zn (Figure 7D and Table 1) which shows that the influence of Rpn8 on the capzimin bound Rpn11 is prominent."

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"PSMD7 interacts with PSMD14 to activate proteasome function to regulate ubiquitinated substrate degradation."
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"For example, USP11 has been found to interact with USP4, USP7 and USP15; and PSMD7 interacts with USP15 and PSMD14 [ xref ]."
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"It is interesting that we, at the first time, reported that PSMD7 knockdown resulted in decreased proliferation and enhanced apoptosis in ESCC cell lines."

eidos
"Knockdown of PSMD7 induces cell cycle arrest , senescence , and apoptosis by regulating cell cycle proteins and the p53 pathway in lung cancer cells ."

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"In ESCC xenografts bearing mice with repression of PSMD7, we also proved that invivo ability of PSMD7 inhibition suppresses tumor growth and induces apoptosis."

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"PSMD7 knockdown inhibits proliferation and induces apoptosis in ESCC cell line."

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"PSMD7 knockdown also led to an increase in apoptosis ( sub-G1 peak ) in H1299 cells but not in A549 cells ( Figure 3C ) ."

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"Knockdown of PSMD7 induces apoptosis and inhibits tumorigenesis in esophageal squamous cell carcinoma 22 ."

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"In conclusion, PSMD7 knockdown inhibits proliferation and induces apoptosis in ESCC cells."

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"In conclusion , PSMD7 knockdown induces cell cycle arrest , senescence and apoptosis in LUAD cells ."

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"These data provided strong evidences that PSMD7 impairment induced apoptosis of ESCC cell lines."

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"Results showed that inhibition of PSMD7 in EC9706 cells caused cell apoptosis with significantly increased numbers of early apoptosis cells and late apoptosis cells (P < 0.05), but made no difference on cell cycle distribution (P> 0.05)."
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"Knockdown of PSMD7 induces apoptosis and inhibits tumorigenesis in esophageal squamous cell carcinoma XREF_BIBR."

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"Knockdown of PSMD7 inhibits tumorigenesis and induces cell apoptosis in esophageal squamous cell carcinoma (ESCC) via the mTOR and p70S6K pathway [XREF_BIBR]."

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"A previous study XREF_BIBR demonstrated that downregulation of PSMD7 led to decreased cell proliferation and increased apoptosis in esophageal squamous cell carcinoma."

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"PSMD7 promoted cell viability, apoptosis resistance, and DNA damage repair in GC cells upon cisplatin (DDP) treatment."

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"Knockdown of PSMD7 induces cell cycle arrest, senescence, and apoptosis by regulating cell cycle proteins and the p53 pathway in lung cancer cells."

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"A high PSMD7 level predicted poor overall survival (OS) and disease-free survival (DFS) in LUAD patients, and PSMD7 knockdown significantly reduced cell proliferation and induced G0/G1-phase cell cycle arrest, cell senescence and apoptosis."

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"Downregulation of PSMD7 by lentivirus mediated shRNA led to decreased proliferation, increased cell apoptosis, and reduced proteasomal function."

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"Knockdown of PSMD7 showed inhibited proliferation and enhanced apoptosis, which is through mTOR and p70S6K signaling pathway."

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"PSMD7 promotes cell cycle progression and suppresses cell senescence and apoptosis of breast cancer cells by regulating the stability of p21 and p2719."

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"Studies have demonstrated that PSMD7 silencing induces proliferation inhibition and apoptosis of ESCC cells, and results in cell cycle arrest, cell senescence, and apoptosis in breast cancer cells18, 19."
PSMD7 bound to PSMD14 activates apoptotic process. 1 / 1
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"We propose that disruption of the PSMD7 and PSMD14 complex may block p53 degradation in the proteasome and therefore trigger cell cycle arrest, senescence and apoptosis in LUAD cells."
P38 affects PSMD7
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"Moreover, we photo-tagged PV-expressing interneurons in the mPFC of PV-cre mice after viral transfection with cre-dependent ChR2(ET/TC) to confirm that FS units at P23–P26 and P38P40 correspond to PV interneurons."

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"The density of SOM-positive neurons was reduced slightly in ES mice at P11–P12 and P38P40, whereas the density of PV-positive neurons was increased significantly at P38P40 ( xref B)."

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"In contrast, evoked activity during acute ramp light stimulation was reduced for RS and FS units in ES mice at P38P40 but normal earlier during development ( xref G and xref C)."

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"A comparison across age revealed that the dendritic length increased with age for control (linear mixed effect model [LMEM]; P11–P12 to P23–P25, ∗∗ p = 0.002; P11–P12 to P38P40, ∗∗∗ p = 0.0002), but not for ES mice (LMEM; P11–P12 to P23–P25, p = 0.79; P11–P12 to P38P40, p = 0.07)."

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"This second peak was reduced significantly in ES mice at P23–P26 and P38P40."

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"In contrast to transient ES at P7–P11, oES only mildly affected the peak frequency, but not the peak strength, of light-induced fast oscillatory activity or multi-unit activity (MUA) at P38P40 ( xref E and 6F)."

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"The material outside the shoulder outer periphery remained unaffected throughout the process, see points P8–P10, P18–P20, P29–P30, and P38P40."
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"For the other areas of material outside the shoulder outer periphery the material movement is negligible, see points P8–P10, P19–P20, P29–P30, and P38P40."
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"Similar to network oscillations, the strength and frequency of the rhythmicity of neuronal firing increased with age, but the magnitude of the increase was lower for ES mice, reaching significance at P38P40 ( xref C)."

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"However, at P38P40, the magnitude of light-induced gamma activity was significantly smaller in ES mice compared with controls."
PSMD7 affects cell cycle
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PSMD7 inhibits cell cycle.
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"A high PSMD7 level predicted poor overall survival (OS) and disease-free survival (DFS) in LUAD patients, and PSMD7 knockdown significantly reduced cell proliferation and induced G0/G1-phase cell cycle arrest, cell senescence and apoptosis."

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"PSMD7 knockdown induced cell cycle arrest, senescence, and apoptosis and suppressed LUAD tumor growth in a xenograft mouse model."

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"Importantly, PSMD7 knockdown induced cell cycle arrest in the G0/G1 phase, leading to cell senescence and apoptosis."

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"These findings indicate that P40 anthocyanin extract inhibits cancer cell growth by inducing cell cycle arrest rather than through a cytotoxic effect."

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"Down-regulated PSMD7 inhibits the expression of key cell cycle related proteins and promotes the stability of p21 and p27 in breast cancer cells [XREF_BIBR]."

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"PSMD7 knockdown induces cell cycle arrest, senescence and apoptosis in LUAD cells."

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"In conclusion, PSMD7 knockdown induces cell cycle arrest, senescence and apoptosis in LUAD cells."

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"Furthermore, knockdown of PSMD7 reduced proliferation and induced cell cycle arrest, senescence and apoptosis by regulating cell cycle proteins and the p53 pathway in tumor cells."
PSMD7 bound to PSMD14 inhibits cell cycle. 1 / 1
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"We propose that disruption of the PSMD7 and PSMD14 complex may block p53 degradation in the proteasome and therefore trigger cell cycle arrest, senescence and apoptosis in LUAD cells."
PSMD7 activates cell cycle.
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eidos
"Importantly , PSMD7 knockdown induced cell cycle arrest in the G0 / G1 phase , leading to cell senescence and apoptosis ."

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"PSMD7 knockdown induced cell cycle arrest , senescence , and apoptosis and suppressed LUAD tumor growth in a xenograft mouse model ."

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"PSMD7 promotes cell cycle progression and suppresses cell senescence and apoptosis of breast cancer cells by regulating the stability of p21 and p2719."

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"Knockdown of PSMD7 induces cell cycle arrest , senescence , and apoptosis by regulating cell cycle proteins and the p53 pathway in lung cancer cells ."

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"PSMD7 knockdown inhibited the expression of key cell cycle related proteins and promoted the stability of p21 and p27 in breast cancer cells."

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"PSMD7 knockdown induces cell cycle arrest , senescence and apoptosis in LUAD cells A previous study 22 demonstrated that downregulation of PSMD7 led to decreased cell proliferation and increased apoptosis in esophageal squamous cell carcinoma ."

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"Knockdown of PSMD7 induces cell cycle arrest, senescence, and apoptosis by regulating cell cycle proteins and the p53 pathway in lung cancer cells."

eidos
"In conclusion , PSMD7 knockdown induces cell cycle arrest , senescence and apoptosis in LUAD cells ."

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"Similar with the findings, Shi et al. has reported that knockdown of PSMD7 induced ESCC apoptosis via a caspase-3 dependent pathway and decreased cells proliferation [XREF_BIBR]."

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"A high PSMD7 level predicted poor overall survival (OS) and disease-free survival (DFS) in LUAD patients, and PSMD7 knockdown significantly reduced cell proliferation and induced G0/G1-phase cell cycle arrest, cell senescence and apoptosis."

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"PSMD7 promotes the proliferation, migration, and invasion of GC cells."

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"MTT and EdU assays consistently demonstrated that PSMD7 knockdown reduced AGS cell proliferation (P < 0.05, Figures 2B and 2C)."

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"PSMD7 was identified as an oncogene in ESCC, and knockdown of PSMD7 induced proliferation inhibition, apoptosis, and mechanistic target of rapamycin (mTOR)/p70S6K pathway inactivation18."

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"A high PSMD7 level predicted poor overall survival ( OS ) and disease-free survival ( DFS ) in LUAD patients , and PSMD7 knockdown significantly reduced cell proliferation and induced G0 / G1-phase cell cycle arrest , cell senescence and apoptosis ."

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"Furthermore, knockdown of PSMD7 reduced proliferation and induced cell cycle arrest, senescence and apoptosis by regulating cell cycle proteins and the p53 pathway in tumor cells."

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"Studies have demonstrated that PSMD7 silencing induces proliferation inhibition and apoptosis of ESCC cells, and results in cell cycle arrest, cell senescence, and apoptosis in breast cancer cells18, 19."

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"In conclusion, PSMD7 knockdown inhibits proliferation and induces apoptosis in ESCC cells."

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"Deubiquitinase PSMD7 promotes the proliferation, invasion, and cisplatin resistance of gastric cancer cells by stabilizing RAD23B."

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"PSMD7 knockdown repressed, whereas PSMD7 overexpression enhanced, the proliferation, migration, and invasion of GC cells."
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"Knockdown of PSMD7 induces cell cycle arrest , senescence , and apoptosis by regulating cell cycle proteins and the p53 pathway in lung cancer cells ."

eidos
"PSMD7 knockdown induces cell cycle arrest , senescence and apoptosis in LUAD cells A previous study 22 demonstrated that downregulation of PSMD7 led to decreased cell proliferation and increased apoptosis in esophageal squamous cell carcinoma ."

eidos
"PSMD7 knockdown induced cell cycle arrest , senescence , and apoptosis and suppressed LUAD tumor growth in a xenograft mouse model ."

eidos
"A high PSMD7 level predicted poor overall survival ( OS ) and disease-free survival ( DFS ) in LUAD patients , and PSMD7 knockdown significantly reduced cell proliferation and induced G0 / G1-phase cell cycle arrest , cell senescence and apoptosis ."

eidos
"In conclusion , PSMD7 knockdown induces cell cycle arrest , senescence and apoptosis in LUAD cells ."

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"Furthermore, knockdown of PSMD7 reduced proliferation and induced cell cycle arrest, senescence and apoptosis by regulating cell cycle proteins and the p53 pathway in tumor cells."

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"PSMD7 knockdown induces cell cycle arrest, senescence and apoptosis in LUAD cells."

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"PSMD7 knockdown induced cell cycle arrest, senescence, and apoptosis and suppressed LUAD tumor growth in a xenograft mouse model."

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"In conclusion, PSMD7 knockdown induces cell cycle arrest, senescence and apoptosis in LUAD cells."
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PSMD7 bound to PSMD14 activates cellular senescence. 1 / 1
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"We propose that disruption of the PSMD7 and PSMD14 complex may block p53 degradation in the proteasome and therefore trigger cell cycle arrest, senescence and apoptosis in LUAD cells."

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"Knockdown of PSMD7 induces cell cycle arrest, senescence, and apoptosis by regulating cell cycle proteins and the p53 pathway in lung cancer cells."
PSMD7 affects RAD23B
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PSMD7 binds RAD23B.
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"The interaction between PSMD7 and RAD23B was further confirmed using the STRING database (Supplementary Figure 4)27."

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"The interaction between PSMD7 and RAD23B was confirmed using protein immunoprecipitation."

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"The interaction between PSMD7 and RAD23B was confirmed using protein immunoprecipitation."

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"In this study, the PIPs and STRING databases were used to predict the interaction between PSMD7 and RAD23B."
PSMD7 deubiquitinates RAD23B.
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PSMD7 deubiquitinates RAD23B. 3 / 3
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"PSMD7 knockdown enhanced the ubiquitination and degradation of RAD23B protein in GC cells."

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"PSMD7 knockdown increased the ubiquitination and degradation of RAD23B in GC cells."

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"PSMD7 promoted cell proliferation, migration, and invasion, and enhanced GC cell resistance to DDP by deubiquitinating and stabilizing RAD23B."
PSMD7 activates RAD23B.
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PSMD7 activates RAD23B. 3 / 3
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"Deubiquitinase PSMD7 promotes the proliferation, invasion, and cisplatin resistance of gastric cancer cells by stabilizing RAD23B."

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"In summary, PSMD7 was highly expressed in GC and contributed to the malignant behavior and DDP resistance of tumor cells by stabilizing RAD23B."

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"PSMD7 enhances the stability of RAD23B via deubiquitination."
PSMD7 increases the amount of RAD23B.
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PSMD7 increases the amount of RAD23B. 1 / 1
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"Then, we found that PSMD7 knockdown reduced, whereas PSMD7 overexpression increased, RAD23B protein levels in GC cells (P < 0.05, Figures 4A and 4B, and Supplementary Figures 3A and 5A)."
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"To investigate the role of RAD23B in PSMD7-induced GC cell proliferation, migration, and invasion, we ectopically expressed RAD23B in AGS cells (P < 0.05, Figure 5A)."

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"PSMD7 knockdown repressed, whereas PSMD7 overexpression enhanced, the proliferation, migration, and invasion of GC cells."

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"Thus, RAD23B participated in PSMD7-enhanced malignant behaviors of GC cells."

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"Thus, PSMD7 promoted the malignant behavior and DDP resistance of GC cells by deubiquitinating and stabilizing RAD23B.In summary, we firstly investigated the overexpression of PSMD7 in GC and verified that PSMD7 has the potential to predict poor prognosis."

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"Furthermore, PSMD7 silencing inhibited GC tumor growth in vivo."

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"Moreover, PSMD7 knockdown suppressed the in vivo growth of GC cells and enhanced the efficiency of DDP treatment for tumor-bearing mice."

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"PSMD7 promotes the proliferation, migration, and invasion of GC cells."

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"PSMD7 promoted cell viability, apoptosis resistance, and DNA damage repair in GC cells upon cisplatin (DDP) treatment."
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"Notably, the upregulation of PSMD7 closely correlated with malignant clinical parameters and reduced the survival of GC patients."

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"As shown in Figure 7A, PSMD7 knockdown significantly repressed GC tumor growth in nude mice (P < 0.05)."
PSMD7 affects TP53
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PSMD7 inhibits TP53.
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PSMD7 inhibits TP53. 3 / 3
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"Furthermore, knockdown of PSMD7 reduced proliferation and induced cell cycle arrest, senescence and apoptosis by regulating cell cycle proteins and the p53 pathway in tumor cells."

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"PSMD7 downregulation suppresses lung cancer progression by regulating the p53 pathway."

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"Depletion of PSMD7 increased p53 levels and induced p21 and puma expression in a p53-dependent manner ."
PSMD7 bound to PSMD14 inhibits TP53. 1 / 1
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"We propose that disruption of the PSMD7 and PSMD14 complex may block p53 degradation in the proteasome and therefore trigger cell cycle arrest, senescence and apoptosis in LUAD cells."
PSMD7 increases the amount of TP53.
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PSMD7 increases the amount of TP53. 2 / 2
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"Depletion of PSMD7 increased p53 levels and induced p21 and puma expression in a p53 dependent manner."

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"Our data show that PSMD7 can also increase p53 protein levels and activate transcription of Mdm2, p21 and Puma in a p53 dependent manner."
PSMD7 activates TP53.
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PSMD7 activates TP53. 2 / 2
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"Knockdown of PSMD7 induces cell cycle arrest, senescence, and apoptosis by regulating cell cycle proteins and the p53 pathway in lung cancer cells."

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"PSMD7 knockdown inhibits tumor growth by activating the p53 pathway."
PSMD7 decreases the amount of TP53.
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PSMD7 decreases the amount of TP53. 1 / 1
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"Depletion of PSMD7 increased p53 levels and induced p21 and puma expression in a p53-dependent manner."
PSMD7 affects PSMC1
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PSMD7 affects PSMD6
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PSMD7 affects PSMD4
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PSMD7 binds PSMD4.
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PSMD7 activates PSMD4.
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PSMD7 activates PSMD4. 1 / 1
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"To reveal the fine structure of the ASF virus capsid, virus particles were treated with 0.5% Nonidet- P40 and 50 mM (8-mercaptoethanol as de- scribed before."
PSMD7 affects PSMD3
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PSMD7 affects PSMD13
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PSMD7 affects PSMC4
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PSMD6 affects PSMD7
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PSMD3 affects PSMD7
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PSMD13 affects PSMD7
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PSMC4 affects PSMD7
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PSMD7 is modified
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PSMD7 is glycosylated.
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PSMD7 is glycosylated. 4 / 4
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"Comparison of the distribution of ^ in various fractions after OST- catalyzed glycosylation of endogenous P40 proteins, i.e. no added tripeptide substrate (line 1), vs that observed in the presenc[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"Competition for the OST active site results in decreased glycosylation of endogenous P40 proteins, thus leading to a decrease in the SDS fraction containing the glycoproteins."

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"Competition for the OST active site results in decreased glycosylation of endogenous P40 proteins, thus leading to a decrease in the SDS fraction containing the glycoproteins."

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"Comparison of the distribution of ^ in various fractions after OST- catalyzed glycosylation of endogenous P40 proteins, i.e. no added tripeptide substrate (line 1), vs that observed in the presenc[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
PSMD7 is acetylated.
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PSMD7 is acetylated on K214. 1 / 1
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PSMD7 is acetylated on K204. 1 / 1
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PSMD7 is phosphorylated.
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PSMD7 is phosphorylated. 1 / 1
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"This phenomenon occurs from the binding of mTOR on C-terminal of the eIF3f subunit, phosphorylating and activating p70 S6K , which is found anchored in the mov34 domain [ xref ]."
PSMD7 affects PSMD12
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PSMD7 affects PSMD11
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PSMD7 affects PSMD1
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PSMD7 affects PSMC5
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PSMD4 affects PSMD7
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PSMD12 affects PSMD7
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PSMD11 affects PSMD7
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PSMD1 affects PSMD7
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PSMC5 affects PSMD7
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Bortezomib affects PSMD7
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Bortezomib inhibits PSMD7.
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Bortezomib increases the amount of PSMD7.
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Bortezomib increases the amount of PSMD7. 1 / 1
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UCHL5 affects PSMD7
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RAD23B affects PSMD7
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RAD23B binds PSMD7.
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"The interaction between PSMD7 and RAD23B was further confirmed using the STRING database (Supplementary Figure 4)27."

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"The interaction between PSMD7 and RAD23B was confirmed using protein immunoprecipitation."

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"The interaction between PSMD7 and RAD23B was confirmed using protein immunoprecipitation."

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"In this study, the PIPs and STRING databases were used to predict the interaction between PSMD7 and RAD23B."
RAD23B activates PSMD7.
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RAD23B activates PSMD7. 1 / 1
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"RAD23B mediates the oncogenic role of PSMD7 in GC cells."
PSMD8 affects PSMD7
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PSMD7 affects UCHL5
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PSMD7 affects PSMD8
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PSMD7 affects PSMD2
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PSMD7 affects PSMD10
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"PSMD7 promotes the proliferation, migration, and invasion of GC cells."

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"Furthermore, transwell assays indicated that PSMD7 silencing significantly inhibited AGS cell migration and invasion (P < 0.05, Figure 2D)."

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"Functionally, we found that PSMD7 knockdown consistently suppressed the proliferation, migration, and invasion of AGS and SGC-7901 cells."

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"Deubiquitinase PSMD7 promotes the proliferation, invasion, and cisplatin resistance of gastric cancer cells by stabilizing RAD23B."

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"PSMD7 knockdown repressed, whereas PSMD7 overexpression enhanced, the proliferation, migration, and invasion of GC cells."
PSMD7 affects EIF3F
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"The leucine charged domain (LCD) of the ubiquitin ligase MAFbx/atrogin-1 physically interacts with the Mov34 domain of eIF3f and contributes to its ubiquitination in the C-terminal region and its subsequent degradation by the proteasome during muscle wasting."

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"MAFbx/atrogin-1 interacts with the Mov34 domain of eIF3f and promotes its ubiquitination resulting in proteasome-mediated degradation of eIF3f during muscle wasting ( xref ) ( xref )."

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"MAFbx/atrogin-1 interacts with the Mov34 domain of eIF3f and promotes its ubiquitination resulting in proteasome-mediated degradation of eIF3f during muscle wasting (Lagirand-Cantaloube et al., 2008) (Fig. 1)."
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"We have demonstrated that CDK11 p46 interacts with the Mov34 domain of eIF3f in vitro and in vivo , and the interaction can be strengthened by the stimulation of apoptosis [ xref ]."
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"Particularly, the inactive hypophosphorylated form of S6K1 physically associates with the Mov34 domain of eIF3f [ xref ]."
PSMD7 affects CDKN1A
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PSMD7 inhibits CDKN1A.
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PSMD7 inhibits CDKN1A. 2 / 2
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"PSMD7 knockdown inhibited the expression of key cell cycle related proteins and promoted the stability of p21 and p27 in breast cancer cells."

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"A previous study indicated that PSMD7 knockdown increased the stability of p21 and p27 in breast cancer cells19."
PSMD7 increases the amount of CDKN1A.
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PSMD7 increases the amount of CDKN1A. 1 / 1
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"Depletion of PSMD7 increased p53 levels and induced p21 and puma expression in a p53 dependent manner."
PSMD7 decreases the amount of CDKN1A.
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PSMD7 decreases the amount of CDKN1A. 1 / 1
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"Depletion of PSMD7 increased p53 levels and induced p21 and puma expression in a p53-dependent manner."
PSMD7 activates CDKN1A.
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PSMD7 activates CDKN1A. 1 / 1
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"PSMD7 promotes cell cycle progression and suppresses cell senescence and apoptosis of breast cancer cells by regulating the stability of p21 and p2719."
PSMD2 affects PSMD7
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PSMD10 affects PSMD7
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EIF3F affects PSMD7
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"The leucine charged domain (LCD) of the ubiquitin ligase MAFbx/atrogin-1 physically interacts with the Mov34 domain of eIF3f and contributes to its ubiquitination in the C-terminal region and its subsequent degradation by the proteasome during muscle wasting."

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"MAFbx/atrogin-1 interacts with the Mov34 domain of eIF3f and promotes its ubiquitination resulting in proteasome-mediated degradation of eIF3f during muscle wasting ( xref ) ( xref )."

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"MAFbx/atrogin-1 interacts with the Mov34 domain of eIF3f and promotes its ubiquitination resulting in proteasome-mediated degradation of eIF3f during muscle wasting (Lagirand-Cantaloube et al., 2008) (Fig. 1)."
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"We have demonstrated that CDK11 p46 interacts with the Mov34 domain of eIF3f in vitro and in vivo , and the interaction can be strengthened by the stimulation of apoptosis [ xref ]."
| 1

sparser
"Particularly, the inactive hypophosphorylated form of S6K1 physically associates with the Mov34 domain of eIF3f [ xref ]."
USP15 affects PSMD7
2 | 1 1
2 | 1

reach
"For example, USP11 has been found to interact with USP4, USP7 and USP15; and PSMD7 interacts with USP15 and PSMD14 [XREF_BIBR]."

No evidence text available

No evidence text available
| 1

sparser
"For example, USP11 has been found to interact with USP4, USP7 and USP15; and PSMD7 interacts with USP15 and PSMD14 [ xref ]."
Porins affects PSMD7
| 1 3
| 1 2

reach
"The results obtained in this study and our earlier study XREF_BIBR indicate that porin interact with both CHIKV and S. odorifera protein P40."

sparser
"Interaction of P40 with mitochondrial protein porin perhaps downregulates the immune response of mosquito."

sparser
"We speculate that like our earlier observation xref , P40-porin interaction could lead to supression of immune response which could be exploited by CHIKV to establish its infection in this mosquito vector."
Porins binds PHB and PSMD7. 1 / 1
| 1

sparser
"In addition, these authors also showed that increased susceptibility of Ae. aegypti to CHIKV mediated by S. odorifera , is due to interaction of the P40 protein of the bacterium with proteins prohibitin and porin present on the midgut of Ae. aegypti that immunosuppress the mosquito, thus accentuating the infection to CHIKV ( xref )."
PSMD7 affects USP15
2 | 1 1
2 | 1

reach
"For example, USP11 has been found to interact with USP4, USP7 and USP15; and PSMD7 interacts with USP15 and PSMD14 [XREF_BIBR]."

No evidence text available

No evidence text available
| 1

sparser
"For example, USP11 has been found to interact with USP4, USP7 and USP15; and PSMD7 interacts with USP15 and PSMD14 [ xref ]."
PSMD7 affects RPS6KB1
| 3 1
PSMD7 activates RPS6KB1.
| 2
PSMD7 activates RPS6KB1. 2 / 2
| 2

reach
"PSMD7 knockdown blocked the expression levels of mTOR and p70S6K invivo, reduced by 33% and 37%, respectively (P < 0.05)."

reach
"These data suggest that inhibition of PSMD7 suppressed the activity of mTOR and p70S6K invivo."
PSMD7 increases the amount of RPS6KB1.
| 1
PSMD7 increases the amount of RPS6KB1. 1 / 1
| 1

reach
"Inhibition of PSMD7 not only reduced the expression of mTOR and p70S6K, but also decreased the expression of p-mTOR Ser2448 and p-p70S6K Thr421 and Ser424, whereas the augmented expression of phosphorylation of mTOR and p70S6K was detected after PSMD7 overexpression in Het-1A cells."
PSMD7 binds RPS6KB1.
| 1
| 1

sparser
"Particularly, the inactive hypophosphorylated form of S6K1 physically associates with the Mov34 domain of eIF3f [ xref ]."
PSMD7 affects Porins
| 1 3
| 1 2

reach
"The results obtained in this study and our earlier study XREF_BIBR indicate that porin interact with both CHIKV and S. odorifera protein P40."

sparser
"Interaction of P40 with mitochondrial protein porin perhaps downregulates the immune response of mosquito."

sparser
"We speculate that like our earlier observation xref , P40-porin interaction could lead to supression of immune response which could be exploited by CHIKV to establish its infection in this mosquito vector."
Porins binds PHB and PSMD7. 1 / 1
| 1

sparser
"In addition, these authors also showed that increased susceptibility of Ae. aegypti to CHIKV mediated by S. odorifera , is due to interaction of the P40 protein of the bacterium with proteins prohibitin and porin present on the midgut of Ae. aegypti that immunosuppress the mosquito, thus accentuating the infection to CHIKV ( xref )."
PSMD7 affects PSMC6
4 |
4 |

No evidence text available

No evidence text available

No evidence text available

No evidence text available
PSMD7 affects PSMC3
4 |
4 |

No evidence text available

No evidence text available

No evidence text available

No evidence text available
PSMD7 affects PSMC2
4 |
4 |

No evidence text available

No evidence text available

No evidence text available

No evidence text available
PSMD7 affects PSMA1
4 |
4 |

No evidence text available

No evidence text available

No evidence text available

No evidence text available
PSMD7 affects PAAF1
4 |
4 |

No evidence text available

No evidence text available

No evidence text available

No evidence text available
PSMD7 affects Neoplasms
| 4
| 4

reach
"Importantly, knockdown of PSMD7 markedly inhibited LUAD tumor growth in a xenograft mouse model."

reach
"Furthermore, PSMD7 silencing inhibited GC tumor growth in vivo."

reach
"Moreover, PSMD7 silencing inhibited tumor growth and enhanced the sensitivity of GC cells to DDP treatment in mice."

reach
"As shown in Figure 7A, PSMD7 knockdown significantly repressed GC tumor growth in nude mice (P < 0.05)."
PSMD7 affects CCNH
| 4
| 4

sparser
"FS units in control mice showed a second peak in their firing rate about 20 ms after the light pulse in P23–P26 and P37P40 mice."

sparser
"During acute light stimulation of ChR2(ET/TC)-transfected L2/3 PYRs (473 nm, square pulse, 1 s), the ratio of excitatory postsynaptic currents (EPSCs) to inhibitory postsynaptic currents (IPSCs) in non-transfected L2/3 PYRs was shifted toward inhibition for P37P40 ES mice compared with controls ( xref D)."

sparser
"According to the established database, 22 type I triterpenes (P6-P8, P20-P29, P41-P43, P63-P66, P74, and P75, xref ), 34 type II triterpenes (P9-P12, P30-P36, P44-P56, and P76-P85, xref ) and 29 type III triterpenes (P1-P5, P13-P19, P37-P40, P57-P62, and P67-P73, xref ) were identified."

sparser
"We performed whole-cell patch-clamp recordings from non-transfected prefrontal L2/3 PYRs in coronal slices, including the mPFC, of control and ES mice at P37P40."
PSMD7 affects ADRM1
4 |
4 |

No evidence text available

No evidence text available

No evidence text available

No evidence text available
PSMC6 affects PSMD7
4 |
4 |

No evidence text available

No evidence text available

No evidence text available

No evidence text available
PSMC3 affects PSMD7
4 |
4 |

No evidence text available

No evidence text available

No evidence text available

No evidence text available
PSMC2 affects PSMD7
4 |
4 |

No evidence text available

No evidence text available

No evidence text available

No evidence text available
PSMA1 affects PSMD7
4 |
4 |

No evidence text available

No evidence text available

No evidence text available

No evidence text available
PAAF1 affects PSMD7
4 |
4 |

No evidence text available

No evidence text available

No evidence text available

No evidence text available
JUN affects PSMD7
4 |
JUN decreases the amount of PSMD7. 4 / 4
4 |

No evidence text available

No evidence text available

No evidence text available

No evidence text available
CCNH affects PSMD7
| 4
| 4

sparser
"FS units in control mice showed a second peak in their firing rate about 20 ms after the light pulse in P23–P26 and P37P40 mice."

sparser
"During acute light stimulation of ChR2(ET/TC)-transfected L2/3 PYRs (473 nm, square pulse, 1 s), the ratio of excitatory postsynaptic currents (EPSCs) to inhibitory postsynaptic currents (IPSCs) in non-transfected L2/3 PYRs was shifted toward inhibition for P37P40 ES mice compared with controls ( xref D)."

sparser
"According to the established database, 22 type I triterpenes (P6-P8, P20-P29, P41-P43, P63-P66, P74, and P75, xref ), 34 type II triterpenes (P9-P12, P30-P36, P44-P56, and P76-P85, xref ) and 29 type III triterpenes (P1-P5, P13-P19, P37-P40, P57-P62, and P67-P73, xref ) were identified."

sparser
"We performed whole-cell patch-clamp recordings from non-transfected prefrontal L2/3 PYRs in coronal slices, including the mPFC, of control and ES mice at P37P40."
ADRM1 affects PSMD7
4 |
4 |

No evidence text available

No evidence text available

No evidence text available

No evidence text available
P30 affects PSMD7
| 3
PSMD7 binds p30. 3 / 3
| 3

sparser
"The burst index of spikes fired within a burst that is followed by a pause of ≥50 ms is significantly different for P21-24 (Z+: 0.0026 ± 0.0006; Z–: 0.0003 ± 0.0001; p = 0.0052 Kruskal–Wallis test; xref D; see also xref B; xref ) and P30-P40 (Z+: 0.0032 ± 0.0013; Z–: 0.0001 ± 0.0001; p = 0.0054 Kruskal-Wallis test; xref D; see also xref )."
| PMC

sparser
"eB-CBE and 1×10 12 vg AAV9-CBE at P30-P40."

sparser
"The animals were maintained in standard housing (SH) or social isolation (P30-P40, SI) conditions."
P25 affects PSMD7
| 3
PSMD7 binds p25. 3 / 3
| 3

sparser
"We next tail vein injected 1.0 mg/kg HA-FMRP(1–297) -tat in P25P40 Fmr1 KO mice (nominally 500 nM plasma concentration at the time of injection) and 30 min or 12 h later processed brains for immunocytochemistry."

sparser
"To monitor changes in the membrane excitability of L2/3 pyramidal neurons, we performed whole-cell patch-clamp recordings in slices (350 μm thick) from S1 cortex of P25P40 mice at near-physiological temperature (31–34°C)."

sparser
"As the RVM matures (e.g., P25P40 in rat), the control over spinal nociceptive circuits transitions to descending inhibition ( xref )."
3 |
Hsa-miR-8076 decreases the amount of PSMD7. 3 / 3
3 |

No evidence text available

No evidence text available

No evidence text available
3 |
Hsa-miR-6874-5p decreases the amount of PSMD7. 3 / 3
3 |

No evidence text available

No evidence text available

No evidence text available
3 |
Hsa-miR-6864-5p decreases the amount of PSMD7. 3 / 3
3 |

No evidence text available

No evidence text available

No evidence text available
3 |
Hsa-miR-6514-5p decreases the amount of PSMD7. 3 / 3
3 |

No evidence text available

No evidence text available

No evidence text available
3 |
Hsa-miR-6500-5p decreases the amount of PSMD7. 3 / 3
3 |

No evidence text available

No evidence text available

No evidence text available
3 |
Hsa-miR-6126 decreases the amount of PSMD7. 3 / 3
3 |

No evidence text available

No evidence text available

No evidence text available
3 |
Hsa-miR-570-5p decreases the amount of PSMD7. 3 / 3
3 |

No evidence text available

No evidence text available

No evidence text available
3 |
Hsa-miR-548ba decreases the amount of PSMD7. 3 / 3
3 |

No evidence text available

No evidence text available

No evidence text available
3 |
Hsa-miR-548ai decreases the amount of PSMD7. 3 / 3
3 |

No evidence text available

No evidence text available

No evidence text available
3 |
Hsa-miR-548ag decreases the amount of PSMD7. 3 / 3
3 |

No evidence text available

No evidence text available

No evidence text available
3 |
Hsa-miR-493-3p decreases the amount of PSMD7. 3 / 3
3 |

No evidence text available

No evidence text available

No evidence text available
3 |
Hsa-miR-4802-5p decreases the amount of PSMD7. 3 / 3
3 |

No evidence text available

No evidence text available

No evidence text available
3 |
Hsa-miR-4633-3p decreases the amount of PSMD7. 3 / 3
3 |

No evidence text available

No evidence text available

No evidence text available
3 |
Hsa-miR-4487 decreases the amount of PSMD7. 3 / 3
3 |

No evidence text available

No evidence text available

No evidence text available
3 |
Hsa-miR-338-5p decreases the amount of PSMD7. 3 / 3
3 |

No evidence text available

No evidence text available

No evidence text available
3 |
Hsa-miR-30e-5p decreases the amount of PSMD7. 3 / 3
3 |

No evidence text available

No evidence text available

No evidence text available
3 |
Hsa-miR-30d-5p decreases the amount of PSMD7. 3 / 3
3 |

No evidence text available

No evidence text available

No evidence text available
3 |
Hsa-miR-30c-5p decreases the amount of PSMD7. 3 / 3
3 |

No evidence text available

No evidence text available

No evidence text available
3 |
Hsa-miR-30b-5p decreases the amount of PSMD7. 3 / 3
3 |

No evidence text available

No evidence text available

No evidence text available
3 |
Hsa-miR-30a-5p decreases the amount of PSMD7. 3 / 3
3 |

No evidence text available

No evidence text available

No evidence text available
3 |
Hsa-miR-1287-5p decreases the amount of PSMD7. 3 / 3
3 |

No evidence text available

No evidence text available

No evidence text available
3 |
Hsa-miR-1277-5p decreases the amount of PSMD7. 3 / 3
3 |

No evidence text available

No evidence text available

No evidence text available
USP14 affects PSMD7
3 |
3 |

No evidence text available

No evidence text available

No evidence text available
SEM1 affects PSMD7
3 |
3 |

No evidence text available

No evidence text available

No evidence text available
PSMD7 affects tumor growth
| 3
PSMD7 activates tumor growth. 3 / 3
| 3

eidos
"Knockdown of PSMD7 inhibited tumor growth in a xenograft mouse model ."

eidos
"PSMD7 knockdown inhibited tumor growth in vivo To assess the effect of PSMD7 on tumor growth in vivo , control and PSMD7-knockdown H1299 cells were subcutaneously injected into nude mice , and the knockdown efficiencies were validated by Western blotting at 24 hours after transfection ."

eidos
"PSMD7 knockdown inhibits tumor growth by activating the p53 pathway Recent studies have demonstrated that p53 is involved in PSMD14-mediated cell proliferation ; p53 is upregulated in PSMD14-knockdown cells , and knockdown of PSMD14 induces cancer cell apoptosis mediated via p53 25 ."
PSMD7 affects p30
| 3
PSMD7 binds p30. 3 / 3
| 3

sparser
"The burst index of spikes fired within a burst that is followed by a pause of ≥50 ms is significantly different for P21-24 (Z+: 0.0026 ± 0.0006; Z–: 0.0003 ± 0.0001; p = 0.0052 Kruskal–Wallis test; xref D; see also xref B; xref ) and P30-P40 (Z+: 0.0032 ± 0.0013; Z–: 0.0001 ± 0.0001; p = 0.0054 Kruskal-Wallis test; xref D; see also xref )."
| PMC

sparser
"eB-CBE and 1×10 12 vg AAV9-CBE at P30-P40."

sparser
"The animals were maintained in standard housing (SH) or social isolation (P30-P40, SI) conditions."
PSMD7 affects p25
| 3
PSMD7 binds p25. 3 / 3
| 3

sparser
"We next tail vein injected 1.0 mg/kg HA-FMRP(1–297) -tat in P25P40 Fmr1 KO mice (nominally 500 nM plasma concentration at the time of injection) and 30 min or 12 h later processed brains for immunocytochemistry."

sparser
"To monitor changes in the membrane excitability of L2/3 pyramidal neurons, we performed whole-cell patch-clamp recordings in slices (350 μm thick) from S1 cortex of P25P40 mice at near-physiological temperature (31–34°C)."

sparser
"As the RVM matures (e.g., P25P40 in rat), the control over spinal nociceptive circuits transitions to descending inhibition ( xref )."
PSMD7 affects cell
| 3
PSMD7 activates cell. 3 / 3
| 3

eidos
"A high PSMD7 level predicted poor overall survival ( OS ) and disease-free survival ( DFS ) in LUAD patients , and PSMD7 knockdown significantly reduced cell proliferation and induced G0 / G1-phase cell cycle arrest , cell senescence and apoptosis ."

eidos
"In conclusion , PSMD7 knockdown induces cell cycle arrest , senescence and apoptosis in LUAD cells ."

eidos
"PSMD7 knockdown induces cell cycle arrest , senescence and apoptosis in LUAD cells A previous study 22 demonstrated that downregulation of PSMD7 led to decreased cell proliferation and increased apoptosis in esophageal squamous cell carcinoma ."
PSMD7 affects USP14
3 |
3 |

No evidence text available

No evidence text available

No evidence text available
PSMD7 affects SEM1
3 |
3 |

No evidence text available

No evidence text available

No evidence text available
PSMD7 affects PSMD5
3 |
3 |

No evidence text available

No evidence text available

No evidence text available
PSMD7 affects PSMB5
2 | 1
2 | 1

No evidence text available

No evidence text available

sparser
"Among the top pairs are also PSMD7-PSMB5, TAGLN-MYL9, and VWA5A- ZCCHC11 (Supplementary Figs.  xref , xref )."
PSMD7 affects PSMB3
3 |
3 |

No evidence text available

No evidence text available

No evidence text available
PSMD7 affects PSMB1
3 |
3 |

No evidence text available

No evidence text available

No evidence text available
PSMD7 affects PSMA7
3 |
3 |

No evidence text available

No evidence text available

No evidence text available
PSMD7 affects PSMA2
3 |
3 |

No evidence text available

No evidence text available

No evidence text available
PSMD7 affects PRSS27
| 3
| 2

sparser
"DDC-Cu and PDTC-Cu inhibit the 26S-proteasomes by interacting with the JAB1/MPN/Mov34 metalloenzyme domain, which is responsible for de-ubiquitination of proteins ( xref ; xref )."

sparser
"DDC-Cu and PDTC-Cu inhibit the 26S-proteasomes by interacting with the JAB1/MPN/Mov34 metalloenzyme domain, which is responsible for de-ubiquitination of proteins (Skrott and Cvek, 2012; Cvek, 2011)."
| 1

sparser
"Based on this alignment, one is tempted to propose that the MPN domain of Mov34 could still be able to form a putative zinc-binding site, composed by Q32, H96, H102, and D105."
PSMD7 affects POLDIP3
| 3
| 2

sparser
"Whereas increasing network activity in developing brains (P12–P18), when axo-axonic synapses are depolarizing, caused a reduction in synapse number, the same manipulation in young adults (P40P46), when axo-axonic synapses are inhibitory, resulted in a small increase in synapse number."

sparser
"Identical manipulations of network activity in older mice (P40P46), when ChC synapses are inhibitory, resulted instead in an increase in axo-axonic synapses."
| 1

sparser
"We have demonstrated that CDK11 p46 interacts with the Mov34 domain of eIF3f in vitro and in vivo , and the interaction can be strengthened by the stimulation of apoptosis [ xref ]."
PSMD7 affects NFKB1
| 3
| 3

sparser
"Two of us (G.L.D. and J.R., 2015) found that transplantation of BM‐MSCs at lower passage numbers (P3‐P8) secreted less BDNF and were less effective in reducing motor deficits than higher passaged (P40P50) BM‐MSCs in R6/2 mice. xref Thus, both the source of the MSCs and the number of times they were passaged can have a significant effect on their therapeutic efficacy."

sparser
"Even in the critical period, DR PSD-93 KO mice did not show jODP (ODI: MD versus no MD, p = 0.5; xref ), whereas DR WT mice exhibited jODP both during the critical period (ODI: MD versus no MD, p < 0.001; xref ) and also after the critical period (P40P50), in contrast to NR WT mice (ODI: DR MD versus NR MD, p < 0.001, xref )."

sparser
"We used FOP and γ-Tubulin antibodies to stain LWs from P40P50 samples, allowing us to observe rotational polarity at the cell and tissue levels (Fig.  xref )."
PSMD7 affects MTOR
| 3
PSMD7 activates MTOR.
| 2
PSMD7 activates MTOR. 2 / 2
| 2

reach
"These data suggest that inhibition of PSMD7 suppressed the activity of mTOR and p70S6K invivo."

reach
"PSMD7 knockdown blocked the expression levels of mTOR and p70S6K invivo, reduced by 33% and 37%, respectively (P < 0.05)."
PSMD7 increases the amount of MTOR.
| 1
PSMD7 increases the amount of MTOR. 1 / 1
| 1

reach
"Inhibition of PSMD7 not only reduced the expression of mTOR and p70S6K, but also decreased the expression of p-mTOR Ser2448 and p-p70S6K Thr421 and Ser424, whereas the augmented expression of phosphorylation of mTOR and p70S6K was detected after PSMD7 overexpression in Het-1A cells."
PSMD7 affects KTN1
3 |
3 |

No evidence text available

No evidence text available

No evidence text available
PSMD7 affects JAG1
| 3
PSMD7 activates JAG1. 3 / 3
| 3

reach
"MTT and EdU assays consistently demonstrated that PSMD7 knockdown reduced AGS cell proliferation (P < 0.05, Figures 2B and 2C)."

reach
"Functionally, we found that PSMD7 knockdown consistently suppressed the proliferation, migration, and invasion of AGS and SGC-7901 cells."

reach
"Furthermore, transwell assays indicated that PSMD7 silencing significantly inhibited AGS cell migration and invasion (P < 0.05, Figure 2D)."
PSMD7 affects GSTO1
| 3
| 3

sparser
"Levels of the D1- and D2-type DA receptors increase until P28P40 and then decline xref – xref , suggesting a toning of the DA response in the striatum over this time."

sparser
"CamKIIα-tTA::TetO-hM3Dq bigenic juvenile male mice received CNO (1 mg/kg; JCNO) via oral administration once daily from P28-P40 ( xref ; xref )."

sparser
"At all ages from P28-P40, median time to complete all tasks (NG, CA, RR, and TT) was longer in the injured group compared to controls; however, the variability in scores was high, and the differences were not consistently statistically significant."
PSMD7 affects Aging
| 3
PSMD7 activates Aging.
| 2
PSMD7 activates Aging. 2 / 2
| 2

reach
"PSMD7 promotes cell cycle progression and suppresses cell senescence and apoptosis of breast cancer cells by regulating the stability of p21 and p2719."

reach
"A high PSMD7 level predicted poor overall survival (OS) and disease-free survival (DFS) in LUAD patients, and PSMD7 knockdown significantly reduced cell proliferation and induced G0/G1-phase cell cycle arrest, cell senescence and apoptosis."
PSMD7 inhibits Aging.
| 1
PSMD7 inhibits Aging. 1 / 1
| 1

reach
"A high PSMD7 level predicted poor overall survival (OS) and disease-free survival (DFS) in LUAD patients, and PSMD7 knockdown significantly reduced cell proliferation and induced G0/G1-phase cell cycle arrest, cell senescence and apoptosis."
PSMD5 affects PSMD7
3 |
3 |

No evidence text available

No evidence text available

No evidence text available
PSMB5 affects PSMD7
2 | 1
2 | 1

No evidence text available

No evidence text available

sparser
"Among the top pairs are also PSMD7-PSMB5, TAGLN-MYL9, and VWA5A- ZCCHC11 (Supplementary Figs.  xref , xref )."
PSMB3 affects PSMD7
3 |
3 |

No evidence text available

No evidence text available

No evidence text available
PSMB1 affects PSMD7
3 |
3 |

No evidence text available

No evidence text available

No evidence text available
PSMA7 affects PSMD7
3 |
3 |

No evidence text available

No evidence text available

No evidence text available
PSMA2 affects PSMD7
3 |
3 |

No evidence text available

No evidence text available

No evidence text available
PRSS27 affects PSMD7
| 3
| 2

sparser
"DDC-Cu and PDTC-Cu inhibit the 26S-proteasomes by interacting with the JAB1/MPN/Mov34 metalloenzyme domain, which is responsible for de-ubiquitination of proteins ( xref ; xref )."

sparser
"DDC-Cu and PDTC-Cu inhibit the 26S-proteasomes by interacting with the JAB1/MPN/Mov34 metalloenzyme domain, which is responsible for de-ubiquitination of proteins (Skrott and Cvek, 2012; Cvek, 2011)."
| 1

sparser
"Based on this alignment, one is tempted to propose that the MPN domain of Mov34 could still be able to form a putative zinc-binding site, composed by Q32, H96, H102, and D105."
POLDIP3 affects PSMD7
| 3
| 2

sparser
"Whereas increasing network activity in developing brains (P12–P18), when axo-axonic synapses are depolarizing, caused a reduction in synapse number, the same manipulation in young adults (P40P46), when axo-axonic synapses are inhibitory, resulted in a small increase in synapse number."

sparser
"Identical manipulations of network activity in older mice (P40P46), when ChC synapses are inhibitory, resulted instead in an increase in axo-axonic synapses."
| 1

sparser
"We have demonstrated that CDK11 p46 interacts with the Mov34 domain of eIF3f in vitro and in vivo , and the interaction can be strengthened by the stimulation of apoptosis [ xref ]."
NFKB1 affects PSMD7
| 3
| 3

sparser
"Two of us (G.L.D. and J.R., 2015) found that transplantation of BM‐MSCs at lower passage numbers (P3‐P8) secreted less BDNF and were less effective in reducing motor deficits than higher passaged (P40P50) BM‐MSCs in R6/2 mice. xref Thus, both the source of the MSCs and the number of times they were passaged can have a significant effect on their therapeutic efficacy."

sparser
"Even in the critical period, DR PSD-93 KO mice did not show jODP (ODI: MD versus no MD, p = 0.5; xref ), whereas DR WT mice exhibited jODP both during the critical period (ODI: MD versus no MD, p < 0.001; xref ) and also after the critical period (P40P50), in contrast to NR WT mice (ODI: DR MD versus NR MD, p < 0.001, xref )."

sparser
"We used FOP and γ-Tubulin antibodies to stain LWs from P40P50 samples, allowing us to observe rotational polarity at the cell and tissue levels (Fig.  xref )."
KTN1 affects PSMD7
3 |
3 |

No evidence text available

No evidence text available

No evidence text available
GSTO1 affects PSMD7
| 3
| 3

sparser
"Levels of the D1- and D2-type DA receptors increase until P28P40 and then decline xref – xref , suggesting a toning of the DA response in the striatum over this time."

sparser
"CamKIIα-tTA::TetO-hM3Dq bigenic juvenile male mice received CNO (1 mg/kg; JCNO) via oral administration once daily from P28-P40 ( xref ; xref )."

sparser
"At all ages from P28-P40, median time to complete all tasks (NG, CA, RR, and TT) was longer in the injured group compared to controls; however, the variability in scores was high, and the differences were not consistently statistically significant."
FOXP3 affects PSMD7
| 1 2
FOXP3 inhibits PSMD7.
| 1
FOXP3 inhibits PSMD7. 1 / 1
| 1

reach
"Overexpression of FOXP3 could rescue the effects of PSMD7 knockdown on gastric cancer cells."
FOXP3 increases the amount of PSMD7.
| 1
FOXP3 increases the amount of PSMD7. 1 / 1
| 1

reach
"FOXP3 was found to bind to PSMD7 promoter and activate PSMD7 expression."
FOXP3 activates PSMD7.
| 1
FOXP3 activates PSMD7. 1 / 1
| 1

eidos
"FOXP3 was found to bind to PSMD7 promoter and activate PSMD7 expression ."
2 |
Valproic acid increases the amount of PSMD7. 2 / 2
2 |

No evidence text available

No evidence text available
Phenylmercury acetate increases the amount of PSMD7. 2 / 2
2 |

No evidence text available

No evidence text available
P90 affects PSMD7
| 2
PSMD7 binds p90. 2 / 2
| 2

sparser
"The major cellular adhesin, P1, localises to the tip of the attachment organelle forming a complex with P40 and P90, two cleavage fragments derived by processing Mpn142, and other molecules with adhesive and mobility functions."

sparser
"This is in agreement with the extensive interface between the P40 and P90 polypeptides indicating that they form a very stable ensemble (according to PISA xref ) (Supplementary Fig.  xref )."
P45 affects PSMD7
| 2
PSMD7 binds p45. 2 / 2
| 2

sparser
"We used ANKS1A KO mice to prepare LWs (P40P45) for 3DSIM analysis."

sparser
"To investigate the role of contrast in defocus perception and refractive eye development, we analyzed the relationship between contrast sensitivity, baseline refractive error, and susceptibility to form-deprivation myopia in eight genetically diverse strains of mice comprising collaborative cross, i.e., 129S1/svlmj, A/J, C57BL/6J, CAST/EiJ, NOD/ShiLtJ, NZO/HlLtJ, PWK/PhJ, and WSB/EiJ mice, at P40-P45."
P42 affects PSMD7
| 2
PSMD7 binds p42. 2 / 2
| 2

sparser
"In addition, structural homology and structure-based sequence alignment establish the presence of a conserved surface exposing a hydrophobic cluster (I39 and P40-P42 at α2–α3 loop and L57 and F61 at α4 helix) that could be responsible for inflammasome assembly and thus, caspase-1 activation [111]."

sparser
"In addition, structural homology and structure-based sequence alignment establish the presence of a conserved surface exposing a hydrophobic cluster (I39 and P40-P42 at α2–α3 loop and L57 and F61 at α4 helix) that could be responsible for inflammasome assembly and thus, caspase-1 activation [ xref ]."
P20 affects PSMD7
| 2
PSMD7 binds p20 and p34. 1 / 1
| 1

sparser
"Co-immunoprecipitation analysis of the interaction between Ac34 and Arp2/3 subunits revealed that Ac34 bound to P40, P34, and P20 of Sf9 cells."
PSMD7 binds p20. 1 / 1
| 1

sparser
"We counted the number of BrdU+ cells in the subgranular zone (SGZ) of the dentate gyrus, in the hippocampus of WT and wv animals that received BNN-20/sal from P14 to P60 with co-administration of BrdU during P20-P40."
Norgestrel affects PSMD7
| 2
| 2

reach
"Methods : The 661W photoreceptor cells and retinal explants from P30 to P40 wild-type (wt) C57BL/6 mice were treated with norgestrel over time."

reach
"The 661W photoreceptor cells and retinal explants from P30 to P40 wild-type (wt) C57BL/6 mice were treated with norgestrel over time."
Indometacin affects PSMD7
2 |
Indometacin increases the amount of PSMD7. 2 / 2
2 |

No evidence text available

No evidence text available
Elongation factor-1-alpha affects PSMD7
| 2
PSMD7 binds elongation factor-1-alpha. 2 / 2
| 2

sparser
"Multiple proteins have been reported to bind to the 3′ UTR of the positive strand of various flaviviruses, including EF-1α and Mov34, which bind to the positive strand 3′ UTR of WNV and JEV, respectively ( xref , xref , xref ), and as many as eight cellular proteins in the case of dengue ( xref )."

sparser
"Multiple proteins have been reported to bind to the 3′ UTR of the positive strand of various flaviviruses, including EF-1α and Mov34, which bind to the positive strand 3′ UTR of WNV and JEV, respectively (Blackwell 1995, Blackwell 1997, Ta 2000), and as many as eight cellular proteins in the case of dengue (De Nova-Ocampo et al., 2002)."
2 |
Cyclosporin A increases the amount of PSMD7.
1 |
Cyclosporin A increases the amount of PSMD7. 1 / 1
1 |

No evidence text available
Cyclosporin A decreases the amount of PSMD7.
1 |
Cyclosporin A decreases the amount of PSMD7. 1 / 1
1 |

No evidence text available
Carfilzomib affects PSMD7
1 1 |
1 1 |

No evidence text available

No evidence text available
Bisphenol A affects PSMD7
2 |
Bisphenol A methylates PSMD7.
1 |
1 |

No evidence text available
Bisphenol A increases the amount of PSMD7.
1 |
Bisphenol A increases the amount of PSMD7. 1 / 1
1 |

No evidence text available
2 |
Benzo[a]pyrene increases the amount of PSMD7. 2 / 2
2 |

No evidence text available

No evidence text available
VPS53 affects PSMD7
2 |
2 |

No evidence text available

No evidence text available
VIM affects PSMD7
1 1 |
1 1 |

No evidence text available

No evidence text available
UBC affects PSMD7
2 |
2 |

No evidence text available

No evidence text available
UBAC1 affects PSMD7
2 |
2 |

No evidence text available

No evidence text available
TRIM11 affects PSMD7
2 |
2 |

No evidence text available

No evidence text available
TRAF6 affects PSMD7
1 1 |
1 1 |

No evidence text available

No evidence text available
SLC2A4 affects PSMD7
1 1 |
1 1 |

No evidence text available

No evidence text available
S100A9 affects PSMD7
| 2
| 2

sparser
"Long-term (P14P40 or P14–P60) administration of the microneurotrophin BNN-20 leads to a significant enhancement (3-fold to 4-fold) of dopaminergic neurogenesis in the SNpc, in a tissue-specific manner, in both WT and wv mice."

sparser
"Daily administration of BNN-20 during P14P40 not only completely abolished further degeneration, but also significantly increased TH+ cell numbers in the SNpc by 26%, in respect to the P14 starting point, indicating the possible induction of a neurogenic process."
RNF20 affects PSMD7
2 |
2 |

No evidence text available

No evidence text available
REX1BD affects PSMD7
2 |
2 |

No evidence text available

No evidence text available
| 2
PSMD7 translocates to the nucleus. 2 / 2
| 2

sparser
"We have demonstrated that Ac34, a viral late-gene product, induces translocation of the P40 subunit of Arp2/3 to the nucleus during AcMNPV infection."

sparser
"We have demonstrated that Ac34, a viral late-gene product, induces translocation of the P40 subunit of Arp2/3 to the nucleus during AcMNPV infection."
PSMD7 affects stability p21 p27 breast cancer cells
| 2
PSMD7 inhibits stability p21 p27 breast cancer cells. 2 / 2
| 2

eidos
"PSMD7 knockdown inhibited the expression of key cell cycle-related proteins and promoted the stability of p21 and p27 in breast cancer cells ."

eidos
"Down-regulated PSMD7 inhibits the expression of key cell cycle-related proteins and promotes the stability of p21 and p27 in breast cancer cells [ 16 ] ."
PSMD7 affects p90
| 2
PSMD7 binds p90. 2 / 2
| 2

sparser
"The major cellular adhesin, P1, localises to the tip of the attachment organelle forming a complex with P40 and P90, two cleavage fragments derived by processing Mpn142, and other molecules with adhesive and mobility functions."

sparser
"This is in agreement with the extensive interface between the P40 and P90 polypeptides indicating that they form a very stable ensemble (according to PISA xref ) (Supplementary Fig.  xref )."
PSMD7 affects p45
| 2
PSMD7 binds p45. 2 / 2
| 2

sparser
"We used ANKS1A KO mice to prepare LWs (P40P45) for 3DSIM analysis."

sparser
"To investigate the role of contrast in defocus perception and refractive eye development, we analyzed the relationship between contrast sensitivity, baseline refractive error, and susceptibility to form-deprivation myopia in eight genetically diverse strains of mice comprising collaborative cross, i.e., 129S1/svlmj, A/J, C57BL/6J, CAST/EiJ, NOD/ShiLtJ, NZO/HlLtJ, PWK/PhJ, and WSB/EiJ mice, at P40-P45."
PSMD7 affects p42
| 2
PSMD7 binds p42. 2 / 2
| 2

sparser
"In addition, structural homology and structure-based sequence alignment establish the presence of a conserved surface exposing a hydrophobic cluster (I39 and P40-P42 at α2–α3 loop and L57 and F61 at α4 helix) that could be responsible for inflammasome assembly and thus, caspase-1 activation [111]."

sparser
"In addition, structural homology and structure-based sequence alignment establish the presence of a conserved surface exposing a hydrophobic cluster (I39 and P40-P42 at α2–α3 loop and L57 and F61 at α4 helix) that could be responsible for inflammasome assembly and thus, caspase-1 activation [ xref ]."
PSMD7 affects p20
| 2
PSMD7 binds p20 and p34. 1 / 1
| 1

sparser
"Co-immunoprecipitation analysis of the interaction between Ac34 and Arp2/3 subunits revealed that Ac34 bound to P40, P34, and P20 of Sf9 cells."
PSMD7 binds p20. 1 / 1
| 1

sparser
"We counted the number of BrdU+ cells in the subgranular zone (SGZ) of the dentate gyrus, in the hippocampus of WT and wv animals that received BNN-20/sal from P14 to P60 with co-administration of BrdU during P20-P40."
PSMD7 affects lung cancer
| 2
| 2

eidos
"PSMD7 downregulation suppresses lung cancer progression by regulating the p53 pathway ."

eidos
"PSMD7 downregulation suppresses lung cancer progression by regulating the p53 pathway Lung cancer is the second most common cancer in both men and women ."
PSMD7 affects key cell cycle-related proteins
| 2
PSMD7 activates key cell cycle-related proteins. 2 / 2
| 2

eidos
"PSMD7 knockdown inhibited the expression of key cell cycle-related proteins and promoted the stability of p21 and p27 in breast cancer cells ."

eidos
"Down-regulated PSMD7 inhibits the expression of key cell cycle-related proteins and promotes the stability of p21 and p27 in breast cancer cells [ 16 ] ."
PSMD7 affects elongation factor-1-alpha
| 2
PSMD7 binds elongation factor-1-alpha. 2 / 2
| 2

sparser
"Multiple proteins have been reported to bind to the 3′ UTR of the positive strand of various flaviviruses, including EF-1α and Mov34, which bind to the positive strand 3′ UTR of WNV and JEV, respectively ( xref , xref , xref ), and as many as eight cellular proteins in the case of dengue ( xref )."

sparser
"Multiple proteins have been reported to bind to the 3′ UTR of the positive strand of various flaviviruses, including EF-1α and Mov34, which bind to the positive strand 3′ UTR of WNV and JEV, respectively (Blackwell 1995, Blackwell 1997, Ta 2000), and as many as eight cellular proteins in the case of dengue (De Nova-Ocampo et al., 2002)."
PSMD7 affects activity
| 2
PSMD7 inhibits activity. 2 / 2
| 2

sparser
"P40 almost completely inhibited the hemolytic activity of C9."

sparser
"P40 almost completely inhibited the hemolytic activity of C9."
PSMD7 affects VPS53
2 |
2 |

No evidence text available

No evidence text available
PSMD7 affects VIM
1 1 |
1 1 |

No evidence text available

No evidence text available
PSMD7 affects UBC
2 |
2 |

No evidence text available

No evidence text available
PSMD7 affects UBAC1
2 |
2 |

No evidence text available

No evidence text available
PSMD7 affects TRIM11
2 |
2 |

No evidence text available

No evidence text available
PSMD7 affects TRAF6
1 1 |
1 1 |

No evidence text available

No evidence text available
PSMD7 affects TIMM8A
| 2
PSMD7 activates TIMM8A. 2 / 2
| 2

reach
"Thus, PSMD7 promoted the malignant behavior and DDP resistance of GC cells by deubiquitinating and stabilizing RAD23B.In summary, we firstly investigated the overexpression of PSMD7 in GC and verified that PSMD7 has the potential to predict poor prognosis."

reach
"Moreover, PSMD7 knockdown suppressed the in vivo growth of GC cells and enhanced the efficiency of DDP treatment for tumor-bearing mice."
PSMD7 affects SLC2A4
1 1 |
1 1 |

No evidence text available

No evidence text available
PSMD7 affects S100A9
| 2
| 2

sparser
"Long-term (P14P40 or P14–P60) administration of the microneurotrophin BNN-20 leads to a significant enhancement (3-fold to 4-fold) of dopaminergic neurogenesis in the SNpc, in a tissue-specific manner, in both WT and wv mice."

sparser
"Daily administration of BNN-20 during P14P40 not only completely abolished further degeneration, but also significantly increased TH+ cell numbers in the SNpc by 26%, in respect to the P14 starting point, indicating the possible induction of a neurogenic process."
PSMD7 affects RNF20
2 |
2 |

No evidence text available

No evidence text available
PSMD7 affects REX1BD
2 |
2 |

No evidence text available

No evidence text available
PSMD7 affects Proteasome
| 2
PSMD7 inhibits Proteasome.
| 1
| 1

reach
"It may also suggest that the decreased proteasome activity was due to the abnormal function of 19S proteasome caused by PSMD7 knockdown."
PSMD7 activates Proteasome.
| 1
PSMD7 bound to PSMD14 activates Proteasome. 1 / 1
| 1

reach
"PSMD7 interacts with PSMD14 to activate proteasome function to regulate ubiquitinated substrate degradation."
PSMD7 affects PSMD7
| 2
PSMD7 increases the amount of PSMD7.
| 1
PSMD7 increases the amount of PSMD7. 1 / 1
| 1

reach
"The quantitative analysis of PSMD7 IHC scores further supported the overexpression of PSMD7 in GC tissues (P = 0.0007, Figure 1B)."
PSMD7 decreases the amount of PSMD7.
| 1
PSMD7 decreases the amount of PSMD7. 1 / 1
| 1

reach
"The protein expression level of PSMD7 was decreased by 63% in shRNA1 lentivirus transfected EC9706 cells compared with the control, so PSMD7 shRNA1 lentivirus can inhibit the expression of PSMD7 in EC9706 cells."
PSMD7 affects PSMB9
2 |
2 |

No evidence text available

No evidence text available
PSMD7 affects PSMB7
2 |
2 |

No evidence text available

No evidence text available
PSMD7 affects PSMB6
2 |
2 |

No evidence text available

No evidence text available
PSMD7 affects PSMB4
2 |
2 |

No evidence text available

No evidence text available
PSMD7 affects PSMB2
2 |
2 |

No evidence text available

No evidence text available
PSMD7 affects PSMA6
2 |
2 |

No evidence text available

No evidence text available
PSMD7 affects PSMA5
2 |
2 |

No evidence text available

No evidence text available
PSMD7 affects PSMA4
2 |
2 |

No evidence text available

No evidence text available
PSMD7 affects PSMA3
2 |
2 |

No evidence text available

No evidence text available
PSMD7 affects NCF1
| 2

sparser
"Further, mild cognitive impairment has been associated with increased expression of P40 PHOX , P47 PHOX , and P67 PHOX in AD brains [ xref ]."
| 1

sparser
"PIP 3 is believed to bind to p47 phox and P40 phox [ xref ]."
PSMD7 affects M
2 |
PSMD7 binds M. 1 / 1
1 |

No evidence text available
PSMD7 binds M. 1 / 1
1 |

No evidence text available
PSMD7 affects LUAD tumor growth
| 2
PSMD7 activates LUAD tumor growth. 2 / 2
| 2

eidos
"Importantly , knockdown of PSMD7 markedly inhibited LUAD tumor growth in a xenograft mouse model ."

eidos
"PSMD7 knockdown induced cell cycle arrest , senescence , and apoptosis and suppressed LUAD tumor growth in a xenograft mouse model ."
PSMD7 affects LRRC15
2 |
2 |

No evidence text available

No evidence text available
PSMD7 affects IFIT3
| 2
| 2

sparser
"After verifying that B6 PV cre -Ai27D mice had acceptable transgene expression, we then examined the effect of P7 ethanol exposure, sex, and laser pulse duration on PV+ IN-mediated oIPSCs in layer V pyramidal neurons in the RSC of both male and female mice at P40P60 using whole-cell patch-clamp electrophysiology."

sparser
"Male and female mice from both P7 vapor chamber exposure conditions were left undisturbed until P40P60 and then processed for immunohistochemistry to analyze both PV expression and ChR2/tdTomato expression."
PSMD7 affects HNSCC
| 2
PSMD7 binds HNSCC.
| 1
PSMD7 binds HNSCC. 1 / 1
| 1

reach
"Then, we focus on the association between PSMD7 and HNSCC."
PSMD7 activates HNSCC.
| 1
PSMD7 activates HNSCC. 1 / 1
| 1

reach
"These results suggested that PSMD7 may promote the occurrence and development of HNSCC."
PSMD7 affects HA
2 |
1 |

No evidence text available
1 |

No evidence text available
PSMD7 affects E6
2 |
1 |

No evidence text available
1 |

No evidence text available
| 2
PSMD7 inhibits Cell Survival.
| 1

reach
"Knockdown of PSMD7 considerably decreased the cell viability with ~ 47% of shPSMD7 group compared to shCon group (P < 0.05), suggesting that inhibition of PSMD7 decreased the survival of EC9706 cells."
PSMD7 activates Cell Survival.
| 1
| 1

reach
"PSMD7 promoted cell viability, apoptosis resistance, and DNA damage repair in GC cells upon cisplatin (DDP) treatment."
| 2

eidos
"Knockdown of PSMD7 inhibits tumorigenesis and induces cell apoptosis in esophageal squamous cell carcinoma ( ESCC ) via the mTOR / p70S6K pathway [ 15 ] ."

eidos
"Knockdown of PSMD7 induces apoptosis and inhibits tumorigenesis in esophageal squamous cell carcinoma 22 ."
PSMD7 affects COPS5
| 2
| 2

sparser
"DDC-Cu and PDTC-Cu inhibit the 26S-proteasomes by interacting with the JAB1/MPN/Mov34 metalloenzyme domain, which is responsible for de-ubiquitination of proteins ( xref ; xref )."

sparser
"DDC-Cu and PDTC-Cu inhibit the 26S-proteasomes by interacting with the JAB1/MPN/Mov34 metalloenzyme domain, which is responsible for de-ubiquitination of proteins (Skrott and Cvek, 2012; Cvek, 2011)."
PSMD7 affects CDR2
2 |
2 |

No evidence text available

No evidence text available
PSMD7 affects CDKN1B
| 2
PSMD7 inhibits CDKN1B. 2 / 2
| 2

reach
"A previous study indicated that PSMD7 knockdown increased the stability of p21 and p27 in breast cancer cells19."

reach
"PSMD7 knockdown inhibited the expression of key cell cycle related proteins and promoted the stability of p21 and p27 in breast cancer cells."
PSMD7 affects CCDC74B
2 |
2 |

No evidence text available

No evidence text available
PSMD7 affects CCDC22
2 |
2 |

No evidence text available

No evidence text available
PSMD7 affects BRAT1
2 |
2 |

No evidence text available

No evidence text available
PSMD7 affects BBC3
| 2
PSMD7 increases the amount of BBC3.
| 1
PSMD7 increases the amount of BBC3. 1 / 1
| 1

reach
"Depletion of PSMD7 increased p53 levels and induced p21 and puma expression in a p53 dependent manner."
PSMD7 decreases the amount of BBC3.
| 1
PSMD7 decreases the amount of BBC3. 1 / 1
| 1

reach
"Depletion of PSMD7 increased p53 levels and induced p21 and puma expression in a p53-dependent manner."
PSMD7 affects ARHGEF5
| 2
| 2

sparser
"Bilateral amygdala lesions were attempted in primed DBA/1 mice of both sexes at P40-P60 and 4-5 days were allowed for recovery before conducting the audiogenic seizure induction trial."

sparser
"In the potential records, P40 and P60 were distributed predominantly ipsilateral to the stimulus (paradoxical lateralization), whereas the P40 and P60 CSDs formed a dipole localized over the contralateral foot somatosensory area."
PSMB9 affects PSMD7
2 |
2 |

No evidence text available

No evidence text available
PSMB7 affects PSMD7
2 |
2 |

No evidence text available

No evidence text available
PSMB6 affects PSMD7
2 |
2 |

No evidence text available

No evidence text available
PSMB4 affects PSMD7
2 |
2 |

No evidence text available

No evidence text available
PSMB2 affects PSMD7
2 |
2 |

No evidence text available

No evidence text available
PSMA6 affects PSMD7
2 |
2 |

No evidence text available

No evidence text available
PSMA5 affects PSMD7
2 |
2 |

No evidence text available

No evidence text available
PSMA4 affects PSMD7
2 |
2 |

No evidence text available

No evidence text available
PSMA3 affects PSMD7
2 |
2 |

No evidence text available

No evidence text available
PRSS27 affects COPS5
| 2
| 2

sparser
"DDC-Cu and PDTC-Cu inhibit the 26S-proteasomes by interacting with the JAB1/MPN/Mov34 metalloenzyme domain, which is responsible for de-ubiquitination of proteins ( xref ; xref )."

sparser
"DDC-Cu and PDTC-Cu inhibit the 26S-proteasomes by interacting with the JAB1/MPN/Mov34 metalloenzyme domain, which is responsible for de-ubiquitination of proteins (Skrott and Cvek, 2012; Cvek, 2011)."
NFE2 affects PSMD7
2 |
NFE2 decreases the amount of PSMD7. 2 / 2
2 |

No evidence text available

No evidence text available
NCF1 affects PSMD7
| 2

sparser
"Further, mild cognitive impairment has been associated with increased expression of P40 PHOX , P47 PHOX , and P67 PHOX in AD brains [ xref ]."
| 1

sparser
"PIP 3 is believed to bind to p47 phox and P40 phox [ xref ]."
M affects PSMD7
2 |
PSMD7 binds M. 1 / 1
1 |

No evidence text available
PSMD7 binds M. 1 / 1
1 |

No evidence text available
LRRC15 affects PSMD7
2 |
2 |

No evidence text available

No evidence text available
IFIT3 affects PSMD7
| 2
| 2

sparser
"After verifying that B6 PV cre -Ai27D mice had acceptable transgene expression, we then examined the effect of P7 ethanol exposure, sex, and laser pulse duration on PV+ IN-mediated oIPSCs in layer V pyramidal neurons in the RSC of both male and female mice at P40P60 using whole-cell patch-clamp electrophysiology."

sparser
"Male and female mice from both P7 vapor chamber exposure conditions were left undisturbed until P40P60 and then processed for immunohistochemistry to analyze both PV expression and ChR2/tdTomato expression."
HA affects PSMD7
2 |
1 |

No evidence text available
1 |

No evidence text available
E6 affects PSMD7
2 |
1 |

No evidence text available
1 |

No evidence text available
COPS5 affects PSMD7
| 2
| 2

sparser
"DDC-Cu and PDTC-Cu inhibit the 26S-proteasomes by interacting with the JAB1/MPN/Mov34 metalloenzyme domain, which is responsible for de-ubiquitination of proteins ( xref ; xref )."

sparser
"DDC-Cu and PDTC-Cu inhibit the 26S-proteasomes by interacting with the JAB1/MPN/Mov34 metalloenzyme domain, which is responsible for de-ubiquitination of proteins (Skrott and Cvek, 2012; Cvek, 2011)."
CDR2 affects PSMD7
2 |
2 |

No evidence text available

No evidence text available
CCDC74B affects PSMD7
2 |
2 |

No evidence text available

No evidence text available
CCDC22 affects PSMD7
2 |
2 |

No evidence text available

No evidence text available
BRAT1 affects PSMD7
2 |
2 |

No evidence text available

No evidence text available
ARHGEF5 affects PSMD7
| 2
| 2

sparser
"Bilateral amygdala lesions were attempted in primed DBA/1 mice of both sexes at P40-P60 and 4-5 days were allowed for recovery before conducting the audiogenic seizure induction trial."

sparser
"In the potential records, P40 and P60 were distributed predominantly ipsilateral to the stimulus (paradoxical lateralization), whereas the P40 and P60 CSDs formed a dipole localized over the contralateral foot somatosensory area."
2,2',4,4',5-brominated diphenyl ether increases the amount of PSMD7.
1 |

No evidence text available
2,2',4,4',5-brominated diphenyl ether decreases the amount of PSMD7.
1 |

No evidence text available
Valdecoxib affects PSMD7
1 |
Valdecoxib increases the amount of PSMD7. 1 / 1
1 |

No evidence text available
Tunicamycin affects PSMD7
1 |
Tunicamycin decreases the amount of PSMD7. 1 / 1
1 |

No evidence text available
Trimellitic anhydride increases the amount of PSMD7. 1 / 1
1 |

No evidence text available
Torcetrapib affects PSMD7
1 |
Torcetrapib increases the amount of PSMD7. 1 / 1
1 |

No evidence text available
Tetrachloromethane increases the amount of PSMD7. 1 / 1
1 |

No evidence text available
Tenuigenin affects PSMD7
1 |
Tenuigenin increases the amount of PSMD7. 1 / 1
1 |

"Tenuigenin could obviously reduce intracerebral Aβ1–40 accumulation in AD mouse brain by increasing the content of 26S proteasome (Chen et al. 2015)"
1 |
Sodium arsenite increases the amount of PSMD7. 1 / 1
1 |

No evidence text available
1 |
Sodium arsenate increases the amount of PSMD7. 1 / 1
1 |

No evidence text available
Sm affects PSMD7
| 1
PSMD7 binds sm. 1 / 1
| 1

sparser
"Moreover, specific egg-derived proteins, including Sm-P40 and thioredoxin peroxidase-1 (Sm-TPx-1), were shown to induce liver lesions and peri-ovular reactions [ xref , xref ]."
SiRNAs cells affects PSMD7
| 1
SiRNAs cells inhibits PSMD7. 1 / 1
| 1

eidos
"PSMD7 expression was largely inhibited by both siRNAs in these cells ( Figure 6A ) ."
SiRNA interference affects PSMD7
| 1
SiRNA interference inhibits PSMD7. 1 / 1
| 1

eidos
"After PSMD7 downregulation by siRNA interference , cell viability , colony-forming capacity and cell apoptosis were analyzed with cell counting kit-8 assay , colony formation assay and terminal deoxynucleotidyl transferasemediated dUTP nick end-labeling ."
1 |
Schizandrin B increases the amount of PSMD7. 1 / 1
1 |

No evidence text available
Rotenone affects PSMD7
1 |
Rotenone decreases the amount of PSMD7. 1 / 1
1 |

No evidence text available
Quinoline affects PSMD7
1 |
Quinoline increases the amount of PSMD7. 1 / 1
1 |

No evidence text available

"Under physiological conditions, UPS, located in the cytosol and the nucleus in eukaryotic cells, as a major intracellular short-lived protein degradation system (Schwartz and Ciechanover 2009), mediates the clearance of misfolded or other abnormally modified proteins with the help of ubiquitin-activating enzyme (E1), ubiquitin-conjugating enzyme (E2), ubiquitin ligase (E3), and the 26S proteasome for the sake of preventing the accumulation of toxic substances (Shang and Taylor 2011)"
Propofol affects PSMD7
| 1
| 1

reach
"Propofol induced significant lengthening of CSEPS (P40 : from 37 +/- 10 up to 41 +/- 11 ms; N50 : from 45 +/- 11 up to 51 +/- 14 ms), and a significant decrease in amplitude (from 1.9 +/- 0.9 down to 0.8 +/- 0.4 microV), but these changes were stable from 30 min after the induction to the end of spine surgery."
1 |
Pirinixic acid increases the amount of PSMD7. 1 / 1
1 |

No evidence text available
1 |

No evidence text available
Phlorizin affects PSMD7
1 |
Phlorizin decreases the amount of PSMD7. 1 / 1
1 |

No evidence text available
1 |

No evidence text available
P34 affects p20
| 1
PSMD7 binds p20 and p34. 1 / 1
| 1

sparser
"Co-immunoprecipitation analysis of the interaction between Ac34 and Arp2/3 subunits revealed that Ac34 bound to P40, P34, and P20 of Sf9 cells."
P31 affects PSMD7
| 1
PSMD7 binds p31. 1 / 1
| 1

sparser
"Most of the material of the bottom sheet, i.e., points P31P40, has no significant movement except for the material around the shoulder periphery, see points P35, P36, and P37."
| PMC
P20 affects p34
| 1
PSMD7 binds p20 and p34. 1 / 1
| 1

sparser
"Co-immunoprecipitation analysis of the interaction between Ac34 and Arp2/3 subunits revealed that Ac34 bound to P40, P34, and P20 of Sf9 cells."
Nefazodone affects PSMD7
1 |
Nefazodone increases the amount of PSMD7. 1 / 1
1 |

No evidence text available
Morphine affects PSMD7
| 1
| 1

reach
"We have previously demonstrated that pre-emptive morphine administration blocks neonatal injury induced thermal and mechanical hypoalgesia in both the injured and uninjured paws in adolescence (P40) and adulthood (P60) [99]."
Miconazole affects PSMD7
1 |
Miconazole increases the amount of PSMD7. 1 / 1
1 |

No evidence text available
Methylmercury chloride increases the amount of PSMD7. 1 / 1
1 |

No evidence text available
Methyl methanesulfonate increases the amount of PSMD7. 1 / 1
1 |

No evidence text available
1 |
Mechlorethamine increases the amount of PSMD7. 1 / 1
1 |

No evidence text available
Leflunomide affects PSMD7
1 |
Leflunomide increases the amount of PSMD7. 1 / 1
1 |

No evidence text available
Last strands beta-sheet affects PSMD7
| 1
Last strands beta-sheet inhibits PSMD7. 1 / 1
| 1

eidos
"Linkage between the N - and C-terminal domains of P1 changes with respect to P40 / P90 , due to the absence of the last two strands in beta-sheet VII ."
Ketone body affects PSMD7
1 |
Ketone body increases the amount of PSMD7. 1 / 1
1 |

No evidence text available
1 |

No evidence text available
Ionomycin affects PSMD7
1 |
Ionomycin increases the amount of PSMD7. 1 / 1
1 |

No evidence text available
| 1

sparser
"Name Clone Nos of aa's Mass (kDa) Comments p 170 Full-length 1382 166.5 p I ! 6 Full-length 873 98.9 pi 10 [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
1 |
Hypochlorous acid increases the amount of PSMD7. 1 / 1
1 |

No evidence text available
1 |
Hsa-miR-5003-5p decreases the amount of PSMD7. 1 / 1
1 |

No evidence text available
1 |
Hsa-miR-331-3p decreases the amount of PSMD7. 1 / 1
1 |

No evidence text available
1 |
Hsa-miR-26b-5p decreases the amount of PSMD7. 1 / 1
1 |

No evidence text available
1 |
Hsa-miR-15b-5p decreases the amount of PSMD7. 1 / 1
1 |

No evidence text available
1 |
Formaldehyde increases the amount of PSMD7. 1 / 1
1 |

No evidence text available
Flutamide affects PSMD7
1 |
Flutamide increases the amount of PSMD7. 1 / 1
1 |

No evidence text available
Finasteride affects PSMD7
1 |
Finasteride increases the amount of PSMD7. 1 / 1
1 |

No evidence text available
Ethanol affects PSMD7
1 |
Ethanol increases the amount of PSMD7. 1 / 1
1 |

No evidence text available
Doxorubicin affects PSMD7
1 |
Doxorubicin decreases the amount of PSMD7. 1 / 1
1 |

No evidence text available
1 |
Dorsomorphin increases the amount of PSMD7. 1 / 1
1 |

No evidence text available
Dobutamine affects PSMD7
| 1
| 1

reach
"Intraperitoneal injection of dobutamine at 0.3 and 1 mg/kg increased HR, FS, and COI of the P30 anesthetized mice and the P40 anesthetized rats, respectively, whereas the percent responses of these parameters in KX animals were greater than those in pentobarbital anesthetized ones due to the lower basal values for the cardiac functional parameters."
1 |
Disodium selenite increases the amount of PSMD7. 1 / 1
1 |

No evidence text available
Dimethyl-4-toluidine decreases the amount of PSMD7. 1 / 1
1 |

No evidence text available
Dicrotophos affects PSMD7
1 |
Dicrotophos decreases the amount of PSMD7. 1 / 1
1 |

No evidence text available
1 |
Dibenzothiophene decreases the amount of PSMD7. 1 / 1
1 |

No evidence text available
Diarsenic trioxide increases the amount of PSMD7. 1 / 1
1 |

No evidence text available
1 |
Dexamethasone increases the amount of PSMD7. 1 / 1
1 |

No evidence text available
Cyt affects XPNPEP2
| 1
| 1

sparser
"The interaction between membrane-bound cyt P40 and cyt b5 is the subject of the investigation presented here."
Cul4 affects PSMD7
| 1
E3_Ub_ligase binds CUL3, PSMD7, and cul4. 1 / 1
| 1

sparser
"NAC1 is a unique POZ/BTB protein ( Cha et al., 1997; Korutla et al., 2002 ), and that binds to Cul3 and Cul4 E3 ubiquitin ligases, and Mov34, a protein in the 26S proteasome subunit ( Shen et al., 200[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
Covalent bonds affects PSMD7
| 1
Covalent bonds inhibits PSMD7. 1 / 1
| 1

eidos
"However , P40 is located at the outer surface part of the Nap and due to the absence of covalent bonds might become separated from P90 and from the Nap complex under stringent or denaturing conditions ."
Copper atom affects PSMD7
1 |
Copper atom increases the amount of PSMD7. 1 / 1
1 |

No evidence text available
1 |
Cobalt dichloride increases the amount of PSMD7. 1 / 1
1 |

No evidence text available
Chelator affects PSMD7
| 1
| 1

reach
"Ovaa et al. reported a mono-Ub probe (Fig. 13e) with a zinc chelator 8-mercaptoquinoline (8-MQ) linked to the C terminus of Ub.129 Inhibition assays showed that the probe can inhibit Rpn11/Rpn8 with an IC50 value about 2 μM."
1 |
Carbon nanotube increases the amount of PSMD7. 1 / 1
1 |

No evidence text available
Capzimin affects PSMD7
| 1
PSMD7 binds capzimin. 1 / 1
| 1

reach
"Binding of capzimin and CSN5i-3 to monomeric Rpn11 and Rpn8-Rpn11 heterodimer."
CAMP-mediated signaling increases the amount of PSMD7. 1 / 1
1 |

"Impairment of 26S proteasome induced by tau can be prevented early in disease through activation of cAMP-PKA signaling, and raising the levels of cAMP with rolipram may enhance tau degradation (Myeku et al. 2016)"
Bisphenol F affects PSMD7
1 |
Bisphenol F increases the amount of PSMD7. 1 / 1
1 |

No evidence text available
Ametryn affects PSMD7
1 |
Ametryn decreases the amount of PSMD7. 1 / 1
1 |

No evidence text available
Allergen affects PSMD7
1 |
Allergen increases the amount of PSMD7. 1 / 1
1 |

No evidence text available
All-trans-retinoic acid increases the amount of PSMD7. 1 / 1
1 |

No evidence text available
Acrylamide affects PSMD7
1 |
Acrylamide increases the amount of PSMD7. 1 / 1
1 |

No evidence text available
YP_009227204 affects PSMD7
1 |
PSMD7 binds YP_009227204. 1 / 1
1 |

No evidence text available
YP_009227203 affects PSMD7
1 |
PSMD7 binds YP_009227203. 1 / 1
1 |

No evidence text available
YP_009227197 affects PSMD7
1 |
PSMD7 binds YP_009227197. 1 / 1
1 |

No evidence text available
XPNPEP2 affects cyt
| 1
| 1

sparser
"The interaction between membrane-bound cyt P40 and cyt b5 is the subject of the investigation presented here."
Vitallium affects PSMD7
1 |
Vitallium increases the amount of PSMD7. 1 / 1
1 |

No evidence text available
1 |
Vehicle Emissions increases the amount of PSMD7. 1 / 1
1 |

No evidence text available
Ubiquitin affects PSMD7
| 1
| 1

sparser
"The ubiquitin activating enzyme Uba1 (E1) and the 19S proteasome regulatory particles Mov34 and Rpn6 have all been implicated in neuronal protein degradation, at least in developmental axon pruning ( xref )."
USP20 affects PSMD7
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1 |

No evidence text available
USP15 affects PSMD14
| 1
| 1

sparser
"For example, USP11 has been found to interact with USP4, USP7 and USP15; and PSMD7 interacts with USP15 and PSMD14 [ xref ]."
UFD1 affects PSMD7
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1 |

No evidence text available
UBLCP1 affects PSMD7
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1 |

No evidence text available
UBB affects PSMD7
1 |
UBB inhibits PSMD7. 1 / 1
1 |

"As is known, the accumulation of frameshift ubiquitin-B (UBB) mutant protein UBB (+1) can block the 26S proteasome in cell lines, and then can reduce Aβ clearance (Hope et al. 2003)"
Tobacco Smoke Pollution increases the amount of PSMD7. 1 / 1
1 |

No evidence text available
TXNL1 affects PSMD7
1 |
1 |

No evidence text available
TST affects PSMD7
1 |
1 |

No evidence text available
TRIM5 affects PSMD7
1 |
1 |

No evidence text available
TRIM21 affects PSMD7
| 1
| 1

sparser
"RNA-seq analysis and coimmunoprecipitation assays indicate that HTR1A interacts with TRIM21 and PSMD7 to inhibit the degradation of TβRII through the ubiquitin-proteasome pathway, thereby inhibiting the transforming growth factor-β (TGF-β) canonical and noncanonical pathway."
TOMM40 affects PSMD7
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1 |

No evidence text available
TH affects PSMD7
| 1
| 1

sparser
"Both during the period of neurodegeneration and neuroplasticity, TH activity in SN was determined by the content of P19-TH, and in the striatum it was determined by P31-TH and P40-TH (to a lesser extent)."
SYVN1 affects PSMD7
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1 |

No evidence text available
SYNCRIP affects PSMD7
1 |
1 |

No evidence text available
STAMBP affects PSMD7
1 |
1 |

No evidence text available
SRXN1 affects PSMD7
1 |
1 |

No evidence text available
SNX20 affects PSMD7
1 |
1 |

No evidence text available
SL affects PSMD7
| 1
PSMD7 binds SL. 1 / 1
| 1

sparser
"Subsequent experiments showed that the MOV34 protein could also bind to the 3 0 SL in native full-length JE virus genomic RNA."
SF3A1 affects PSMD7
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1 |

No evidence text available
SEPSECS affects PSMD7
| 1
| 1

sparser
"Moreover, P40-LP displayed a synergistic effect with IPB24 lipopeptide that was designed containing the C-terminally extended residues, and it could effectively inhibit other human coronaviruses, including SARS-CoV, MERS-CoV, HCoV-229E, and HCoV-NL63."
RVM affects PSMD7
| 1
RVM activates PSMD7. 1 / 1
| 1

reach
"Using quantitative electromyographic measurement of reflex sensitivity, we identified increased RVM mediated inhibition across all stimulus intensities at P40."
RPS6KB1 affects PSMD7
| 1
| 1

sparser
"Particularly, the inactive hypophosphorylated form of S6K1 physically associates with the Mov34 domain of eIF3f [ xref ]."
RPS13 affects PSMD7
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1 |

No evidence text available
RPN8 affects PSMD7
| 1
| 1

sparser
"Among these genes, RpL14, RpS24, and Rpn8 are associated with heart phenotypes."
RPN11 affects PSMD7
| 1
| 1

reach
"PSMD14 and Rpn11 forms a dimer with PSMD7 and Rpn8 and catalyzes deubiquitylation."
RPGRIP1L affects PSMD7
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No evidence text available
RNF11 affects PSMD7
1 |
1 |

No evidence text available
| 1

sparser
"Name Clone Nos of aa's Mass (kDa) Comments p 170 Full-length 1382 166.5 p I ! 6 Full-length 873 98.9 pi 10 [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
RGPD5 affects PSMD7
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1 |

No evidence text available
RAD23A affects PSMD7
1 |
1 |

No evidence text available
RAB1A affects PSMD7
1 |
1 |

No evidence text available
Proteasome affects PSMD7
| 1
Proteasome decreases the amount of PSMD7. 1 / 1
| 1

reach
"RBSDV accumulation in L. striatellus increased after the 26S proteasome was disrupted by silencing the RPN8 expression."
Porins affects PHB
| 1
Porins binds PHB and PSMD7. 1 / 1
| 1

sparser
"In addition, these authors also showed that increased susceptibility of Ae. aegypti to CHIKV mediated by S. odorifera , is due to interaction of the P40 protein of the bacterium with proteins prohibitin and porin present on the midgut of Ae. aegypti that immunosuppress the mosquito, thus accentuating the infection to CHIKV ( xref )."
1 |
Plant Extracts increases the amount of PSMD7. 1 / 1
1 |

No evidence text available
PSMG2 affects PSMD7
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1 |

No evidence text available
PSME2 affects PSMD7
1 |
1 |

No evidence text available
PSMD9 affects PSMD7
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1 |

No evidence text available
PSMD7 affects γ-H2AX protein
| 1
PSMD7 decreases the amount of γ-H2AX protein. 1 / 1
| 1

reach
"PSMD7 significantly inhibited DDP-induced apoptosis and γ-H2AX protein expression in GC cells."
PSMD7 affects various human immune cells including CD4 T cell
| 1
PSMD7 activates various human immune cells including CD4 T cell. 1 / 1
| 1

eidos
"In the present study , high expression of PSMD7 was associated with activating of various human immune cells , including CD4 + T cell , CD8 + T cells , Tregs et al. Intron retention ( IR ) is one of the major forms of alternative splicing in eukaryotes ."
PSMD7 affects transcription Mdm2 p21
| 1
PSMD7 activates transcription Mdm2 p21. 1 / 1
| 1

eidos
"Our data show that PSMD7 can also increase p53 protein levels and activate transcription of Mdm2 , p21 and Puma in a p53-dependent manner ."
PSMD7 affects sm
| 1
PSMD7 binds sm. 1 / 1
| 1

sparser
"Moreover, specific egg-derived proteins, including Sm-P40 and thioredoxin peroxidase-1 (Sm-TPx-1), were shown to induce liver lesions and peri-ovular reactions [ xref , xref ]."
PSMD7 affects set proteins regulating cell cycle
| 1
PSMD7 activates set proteins regulating cell cycle. 1 / 1
| 1

eidos
"PSMD7 knockdown inhibited expression of a set of proteins regulating cell cycle progression ."
PSMD7 affects ratio of BG
| 1
PSMD7 activates ratio of BG. 1 / 1
| 1

eidos
"P addition alone increased enzyme activity , and P40 addition increased the ratio of BG to soil microbial biomass carbon ( MBC ) , and ( NAG + LAP ) : MBC activity ratio , thereby aggravating C restriction ."
PSMD7 affects protein
1 |
PSMD7 decreases the amount of protein. 1 / 1
1 |

"Under physiological conditions, UPS, located in the cytosol and the nucleus in eukaryotic cells, as a major intracellular short-lived protein degradation system (Schwartz and Ciechanover 2009), mediates the clearance of misfolded or other abnormally modified proteins with the help of ubiquitin-activating enzyme (E1), ubiquitin-conjugating enzyme (E2), ubiquitin ligase (E3), and the 26S proteasome for the sake of preventing the accumulation of toxic substances (Shang and Taylor 2011)"
PSMD7 affects proteasome function
| 1
PSMD7 activates proteasome function. 1 / 1
| 1

eidos
"PSMD7 interacts with PSMD14 to activate proteasome function to regulate ubiquitinated substrate degradation ."
PSMD7 affects p53 protein
| 1
PSMD7 activates p53 protein. 1 / 1
| 1

eidos
"Our data show that PSMD7 can also increase p53 protein levels and activate transcription of Mdm2 , p21 and Puma in a p53-dependent manner ."
PSMD7 affects p34
| 1
PSMD7 binds p20 and p34. 1 / 1
| 1

sparser
"Co-immunoprecipitation analysis of the interaction between Ac34 and Arp2/3 subunits revealed that Ac34 bound to P40, P34, and P20 of Sf9 cells."
PSMD7 affects p31
| 1
PSMD7 binds p31. 1 / 1
| 1

sparser
"Most of the material of the bottom sheet, i.e., points P31P40, has no significant movement except for the material around the shoulder periphery, see points P35, P36, and P37."
| PMC
PSMD7 affects p2719
| 1
PSMD7 activates p2719. 1 / 1
| 1

reach
"PSMD7 promotes cell cycle progression and suppresses cell senescence and apoptosis of breast cancer cells by regulating the stability of p21 and p2719."
PSMD7 affects p21 puma
| 1
PSMD7 inhibits p21 puma. 1 / 1
| 1

eidos
"Depletion of PSMD7 increased p53 levels and induced p21 and puma expression in a p53-dependent manner ."
PSMD7 affects p20, and p34
| 1
PSMD7 binds p20 and p34. 1 / 1
| 1

sparser
"Co-immunoprecipitation analysis of the interaction between Ac34 and Arp2/3 subunits revealed that Ac34 bound to P40, P34, and P20 of Sf9 cells."
| 1
| 1

eidos
"The P40 promoter initiates the transcription of the Cap gene and produces two mRNAs by alternative splicing [ 55 ] ."
| PMC
PSMD7 affects long-term HI SVZ microglia
| 1
PSMD7 activates long-term HI SVZ microglia. 1 / 1
| 1

eidos
"Even though the phagocytic nature of these microglial ball-and-chain protrusions is not fully ascertained , their increased proportion at P40 underlines the long-term effects of HI on SVZ microglia ."
PSMD7 affects lipoprotein
| 1
| 1

reach
"Fujiflavone P40 also decreased total and high-density lipoprotein (HDL) cholesterols and triglyceride level of OVX rats, significantly."
PSMD7 affects isoflavone
| 1
| 1

reach
"Fujiflavone P40 (a product of isoflavone from soybeans) was kindly supplied by Fujicco (Kobe, Japan) [21]."
PSMD7 affects intu
| 1

sparser
"Name Clone Nos of aa's Mass (kDa) Comments p 170 Full-length 1382 166.5 p I ! 6 Full-length 873 98.9 pi 10 [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

reach
"This study was designed to determine the effects of twice daily tooth brushing with the Sonicare Elite (Elite) and the Oral-B P40 manual toothbrush (MTB) on plaque accumulation and plaque induced gingival inflammation."
| 1

reach
"Interaction of P40 with mitochondrial protein porin perhaps downregulates the immune response of mosquito."
PSMD7 affects extracellular protein
| 1
PSMD7 activates extracellular protein. 1 / 1
| 1

reach
"We noticed that P40 almost did not consume lactose, produced less biomass and started to produce extracellular protein and cellulases later than P58."
PSMD7 affects development HNSCC
| 1
PSMD7 activates development HNSCC. 1 / 1
| 1

eidos
"These results suggested that PSMD7 may promote the occurrence and development of HNSCC ."
PSMD7 affects cyt
| 1
| 1

sparser
"The interaction between membrane-bound cyt P40 and cyt b5 is the subject of the investigation presented here."
PSMD7 affects cul4
| 1
E3_Ub_ligase binds CUL3, PSMD7, and cul4. 1 / 1
| 1

sparser
"NAC1 is a unique POZ/BTB protein ( Cha et al., 1997; Korutla et al., 2002 ), and that binds to Cul3 and Cul4 E3 ubiquitin ligases, and Mov34, a protein in the 26S proteasome subunit ( Shen et al., 200[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
PSMD7 affects cisplatin
| 1
| 1

reach
"Deubiquitinase PSMD7 promotes the proliferation, invasion, and cisplatin resistance of gastric cancer cells by stabilizing RAD23B."
PSMD7 affects cells previous
| 1
PSMD7 activates cells previous. 1 / 1
| 1

eidos
"PSMD7 knockdown induces cell cycle arrest , senescence and apoptosis in LUAD cells A previous study 22 demonstrated that downregulation of PSMD7 led to decreased cell proliferation and increased apoptosis in esophageal squamous cell carcinoma ."
| 1

reach
"Furthermore, transwell assays indicated that PSMD7 silencing significantly inhibited AGS cell migration and invasion (P < 0.05, Figure 2D)."
PSMD7 affects cell growth
| 1
| 1

reach
"These findings indicate that P40 anthocyanin extract inhibits cancer cell growth by inducing cell cycle arrest rather than through a cytotoxic effect."
| 1

reach
"A high PSMD7 level predicted poor overall survival (OS) and disease-free survival (DFS) in LUAD patients, and PSMD7 knockdown significantly reduced cell proliferation and induced G0/G1-phase cell cycle arrest, cell senescence and apoptosis."
PSMD7 affects cell apoptosis
| 1
PSMD7 inhibits cell apoptosis. 1 / 1
| 1

eidos
"Knockdown of PSMD7 inhibits tumorigenesis and induces cell apoptosis in esophageal squamous cell carcinoma ( ESCC ) via the mTOR / p70S6K pathway [ 15 ] ."
PSMD7 affects ced-3
| 1
PSMD7 inhibits ced-3. 1 / 1
| 1

reach
"As shown in XREF_FIG, overexpression of P40 suppressed ced-3 (lf) much better than that of full length GSNL-1."
PSMD7 affects cardiac structural function
| 1
PSMD7 activates cardiac structural function. 1 / 1
| 1

eidos
"Of note , DNHD1 , GSE1 , and PSMD7 may contribute to cardiac structural function ."
PSMD7 affects capzimin
| 1
PSMD7 binds capzimin. 1 / 1
| 1

reach
"Binding of capzimin and CSN5i-3 to monomeric Rpn11 and Rpn8-Rpn11 heterodimer."
PSMD7 affects accumulation activation p53
| 1
PSMD7 inhibits accumulation activation p53. 1 / 1
| 1

eidos
"Our results showed that p53 , Mdm2 , p21 and Puma protein levels increased after PSMD7 knockdown in p53 wild-type A549 cells but remained steady or slightly decreased in p53-null H1299 cells ( Figure 5A ) , suggesting that PSMD7 depletion leads to the accumulation and activation of p53 ."
PSMD7 affects YP_009227204
1 |
PSMD7 binds YP_009227204. 1 / 1
1 |

No evidence text available
PSMD7 affects YP_009227203
1 |
PSMD7 binds YP_009227203. 1 / 1
1 |

No evidence text available
PSMD7 affects YP_009227197
1 |
PSMD7 binds YP_009227197. 1 / 1
1 |

No evidence text available
PSMD7 affects XPNPEP2, and cyt
| 1
| 1

sparser
"The interaction between membrane-bound cyt P40 and cyt b5 is the subject of the investigation presented here."
PSMD7 affects USP20
1 |
1 |

No evidence text available
PSMD7 affects UFD1
1 |
1 |

No evidence text available
PSMD7 affects UBLCP1
1 |
1 |

No evidence text available
PSMD7 affects UALCAN was database analyze mRNA profiles
| 1
PSMD7 activates UALCAN was database analyze mRNA profiles. 1 / 1
| 1

eidos
"Association of PSMD7 expression and clinicopathological characteristics Because expression of PSMD7 was significantly up-regulated in HNSCC tissues , then the UALCAN was the used database to analyze the mRNA expression profiles of PSMD7 based on clinicopathological parameters ."
PSMD7 affects TXNL1
1 |
1 |

No evidence text available
PSMD7 affects TUNEL
| 1
PSMD7 activates TUNEL. 1 / 1
| 1

reach
"PSMD7 knockdown markedly reduced the percentage of Ki-67 positive cells but increased the number of TUNEL-stained cells in xenograft tumor tissues with or without DDP treatment (P < 0.05, Figure 7C and Supplementary Figure 8)."
PSMD7 affects TST
1 |
1 |

No evidence text available
PSMD7 affects TRIM5
1 |
1 |

No evidence text available
PSMD7 affects TRIM21
| 1
| 1

sparser
"RNA-seq analysis and coimmunoprecipitation assays indicate that HTR1A interacts with TRIM21 and PSMD7 to inhibit the degradation of TβRII through the ubiquitin-proteasome pathway, thereby inhibiting the transforming growth factor-β (TGF-β) canonical and noncanonical pathway."
PSMD7 affects TOMM40
1 |
1 |

No evidence text available
PSMD7 affects TH
| 1
| 1

sparser
"Both during the period of neurodegeneration and neuroplasticity, TH activity in SN was determined by the content of P19-TH, and in the striatum it was determined by P31-TH and P40-TH (to a lesser extent)."
PSMD7 affects SYVN1
1 |
1 |

No evidence text available
PSMD7 affects SYNCRIP
1 |
1 |

No evidence text available
PSMD7 affects STAMBP
1 |
1 |

No evidence text available
PSMD7 affects SRXN1
1 |
1 |

No evidence text available
PSMD7 affects SNX20
1 |
1 |

No evidence text available
PSMD7 affects SL
| 1
PSMD7 binds SL. 1 / 1
| 1

sparser
"Subsequent experiments showed that the MOV34 protein could also bind to the 3 0 SL in native full-length JE virus genomic RNA."
PSMD7 affects SF3A1
1 |
1 |

No evidence text available
PSMD7 affects SEPSECS
| 1
| 1

sparser
"Moreover, P40-LP displayed a synergistic effect with IPB24 lipopeptide that was designed containing the C-terminally extended residues, and it could effectively inhibit other human coronaviruses, including SARS-CoV, MERS-CoV, HCoV-229E, and HCoV-NL63."
PSMD7 affects RPS13
1 |
1 |

No evidence text available
PSMD7 affects RPN8
| 1
| 1

sparser
"Among these genes, RpL14, RpS24, and Rpn8 are associated with heart phenotypes."
PSMD7 affects RPN11
| 1
| 1

reach
"PSMD14 and Rpn11 forms a dimer with PSMD7 and Rpn8 and catalyzes deubiquitylation."
PSMD7 affects RPGRIP1L
1 |

No evidence text available
PSMD7 affects RNF11
1 |
1 |

No evidence text available
| 1

sparser
"Name Clone Nos of aa's Mass (kDa) Comments p 170 Full-length 1382 166.5 p I ! 6 Full-length 873 98.9 pi 10 [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
PSMD7 affects RGPD5
1 |
1 |

No evidence text available
PSMD7 affects RAD23A
1 |
1 |

No evidence text available
PSMD7 affects RAB1A
1 |
1 |

No evidence text available
| 1

reach
"This study indicated that the proportion of P40 : C60 in the diet produced the best efficiency of urinary PD excretion (mmol) per digestible OM intake (kg DOMI)."
PSMD7 affects PTHLH
| 1
PSMD7 activates PTHLH. 1 / 1
| 1

reach
"By P40, PLP immunostaining increased in the JOE cortex, but not nearly to the extent that might have been predicted by the loss of the tremors (XREF_FIG)."
PSMD7 affects PSMG2
1 |
1 |

No evidence text available
PSMD7 affects PSME2
1 |
1 |

No evidence text available
PSMD7 affects PSMD9
1 |
1 |

No evidence text available
PSMD7 affects PSMB8
1 |
1 |

No evidence text available
PSMD7 affects PSMA8
1 |
1 |

No evidence text available
PSMD7 affects PRKN
1 |
1 |

No evidence text available
PSMD7 affects PRF1
| 1
| 1

sparser
"To understand the local material flow behavior further, the time-averaged velocities of the analysed points for material flow i.e., points P1P40 during the refill FSSW are shown in xref ."
| PMC
PSMD7 affects PON1
| 1
| 1

sparser
"Superimposition of the RGD loop (residues K21-D30) and C-terminus (residues P40-K45) resulted in RMSD values of 0.162 Å and 0.581 Å, respectively ( xref D,E)."
PSMD7 affects PHOX2B
| 1

sparser
"Further, mild cognitive impairment has been associated with increased expression of P40 PHOX , P47 PHOX , and P67 PHOX in AD brains [ xref ]."
PSMD7 affects PHB
| 1
Porins binds PHB and PSMD7. 1 / 1
| 1

sparser
"In addition, these authors also showed that increased susceptibility of Ae. aegypti to CHIKV mediated by S. odorifera , is due to interaction of the P40 protein of the bacterium with proteins prohibitin and porin present on the midgut of Ae. aegypti that immunosuppress the mosquito, thus accentuating the infection to CHIKV ( xref )."
PSMD7 affects PB2
1 |
1 |

No evidence text available
PSMD7 affects PB1
1 |
1 |

No evidence text available
PSMD7 affects PA
1 |
1 |

No evidence text available
PSMD7 affects P78/83
| 1
PSMD7 binds P78/83. 1 / 1
| 1

reach
"In addition, co-immunoprecipitation assay demonstrated that P40 interacted with P78/83 only in virus infected cells, suggesting that actin polymerization induced by P78/83-Arp 2/3 complex during baculovirus infection was regulated by some unidentified virus factors."

reach
"Further investigations revealed that P9-1 could competitively bind to RPN8 with RPN7, thereby disrupting the assembly of 26S proteasome in L. striatellus and promoting the infection of RBSDV in insect vectors, and further affecting the transmission of the virus to rice by insect vectors."
PSMD7 affects P150 Sca1
| 1
PSMD7 activates P150 Sca1. 1 / 1
| 1

reach
"Measurement of expression intensities for Calbindin from the perikaryon center along the dendrites revealed that PCs from P150 Sca1 154Q/2Q mice which had been treated with MitoQ from P40 onwards had [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
PSMD7 affects P100
| 1
| 1

reach
"We were able to show that the recombinant P40 can also interact preferentially with P100, when compared to P26, which corresponds to the C-terminal portion of OTI-VIT-6."
PSMD7 affects OFD1
1 |
1 |

No evidence text available
PSMD7 affects ODF1
1 |
1 |

No evidence text available
PSMD7 affects O41946
1 |
1 |

No evidence text available
PSMD7 affects Nα-acetyl
| 1
MYL9 binds HEXIM2, PSMD7, and Nα-acetyl. 1 / 1
| 1

sparser
"The increased binding of PSMD7 and HEXIM2 to Nα-acetyl-MYL9 did not reproduce but the decreased binding of Cofilin-1 to Nα-methyl-MYL9 was reproducible ( xref )."
PSMD7 affects NTRK1
1 |
1 |

No evidence text available
PSMD7 affects NP_579894
1 |
PSMD7 binds NP_579894. 1 / 1
1 |

No evidence text available
PSMD7 affects NPHP1
1 |
1 |

No evidence text available
PSMD7 affects NOS2
1 |
1 |

No evidence text available
PSMD7 affects NFKB2
| 1
| 1

sparser
"We were able to show that the recombinant P40 can also interact preferentially with P100, when compared to P26, which corresponds to the C-terminal portion of OTI-VIT-6."
PSMD7 affects NDUFV1
1 |
1 |

No evidence text available
PSMD7 affects NCF2
| 1

sparser
"Further, mild cognitive impairment has been associated with increased expression of P40 PHOX , P47 PHOX , and P67 PHOX in AD brains [ xref ]."
PSMD7 affects NACC1
1 |
1 |

No evidence text available
PSMD7 affects NA
1 |
1 |

No evidence text available
PSMD7 affects Mice
| 1
PSMD7 activates Mice. 1 / 1
| 1

reach
"Moreover, PSMD7 knockdown suppressed the in vivo growth of GC cells and enhanced the efficiency of DDP treatment for tumor-bearing mice."
PSMD7 affects MYL9
| 1
MYL9 binds HEXIM2, PSMD7, and Nα-acetyl. 1 / 1
| 1

sparser
"The increased binding of PSMD7 and HEXIM2 to Nα-acetyl-MYL9 did not reproduce but the decreased binding of Cofilin-1 to Nα-methyl-MYL9 was reproducible ( xref )."
PSMD7 affects MTCH1
1 |
1 |

No evidence text available
PSMD7 affects MT-ATP6
| 1
| 1

sparser
"Among these genes, RpL14, RpS24, and Rpn8 are associated with heart phenotypes."
PSMD7 affects MS-MS method
| 1
PSMD7 inhibits MS-MS method. 1 / 1
| 1

eidos
"As the subunit of 26S proteasome , PSMD7 was found to be decreased after 36 h irradiation using MS-MS method [ 26 ] ."
PSMD7 affects MRPS16
1 |
1 |

No evidence text available
PSMD7 affects MMEL1
| 1
| 1

sparser
"Interestingly, it has been shown that clinical neurophysiological parameters obtained from the lower extremities, like the P40-SEP, H-reflex and nociceptive RIII reflex were lowered in the “on” condition of the SCS stimulator."
PSMD7 affects MME
| 1
| 1

sparser
"The polypeptides interacting with P40 were further characterized using MALDI-TOF/TOF analysis."
PSMD7 affects MID1
1 |
1 |

No evidence text available
PSMD7 affects MED4
1 |
1 |

No evidence text available
PSMD7 affects MED23
1 |
1 |

No evidence text available
PSMD7 affects MCFD2
1 |
1 |

No evidence text available
PSMD7 affects LUAD
| 1
PSMD7 activates LUAD. 1 / 1
| 1

reach
"Importantly, knockdown of PSMD7 markedly inhibited LUAD tumor growth in a xenograft mouse model."
PSMD7 affects LMP2
1 |
1 |

No evidence text available
PSMD7 affects KCMF1
1 |
1 |

No evidence text available
PSMD7 affects INTU
1 |
1 |

No evidence text available
PSMD7 affects ID1
| 1
| 1

sparser
"In the CC at P40, ID was associated with reduced peak amplitudes of compound action potentials specific to myelinated axons, in which diameters were reduced by ∼20% compared with Fe+ controls."
PSMD7 affects HUWE1
1 |
1 |

No evidence text available
PSMD7 affects HTR1A
| 1
| 1

sparser
"RNA-seq analysis and coimmunoprecipitation assays indicate that HTR1A interacts with TRIM21 and PSMD7 to inhibit the degradation of TβRII through the ubiquitin-proteasome pathway, thereby inhibiting the transforming growth factor-β (TGF-β) canonical and noncanonical pathway."
PSMD7 affects HTLV-1 enhancer
| 1
PSMD7 activates HTLV-1 enhancer. 1 / 1
| 1

reach
"A transcriptional trans-activator P40 tax of HTLV-1 was reported to activate HTLV-1 enhancer, but not SV40 or Rous sarcoma virus enhancer."
PSMD7 affects HSD17B10
1 |

No evidence text available
PSMD7 affects HNSCC cells growth
| 1
PSMD7 activates HNSCC cells growth. 1 / 1
| 1

eidos
"Importantly , knockdown of PSMD7 significantly inhibited HNSCC cells growth ."
PSMD7 affects HIV1gp8
1 |
PSMD7 binds HIV1gp8. 1 / 1
1 |

No evidence text available
PSMD7 affects HIV1gp4
1 |
PSMD7 binds HIV1gp4. 1 / 1
1 |

No evidence text available
PSMD7 affects HEXIM2
| 1
MYL9 binds HEXIM2, PSMD7, and Nα-acetyl. 1 / 1
| 1

sparser
"The increased binding of PSMD7 and HEXIM2 to Nα-acetyl-MYL9 did not reproduce but the decreased binding of Cofilin-1 to Nα-methyl-MYL9 was reproducible ( xref )."
PSMD7 affects HCFC1
1 |
1 |

No evidence text available
PSMD7 affects H1299 cells
| 1
PSMD7 inhibits H1299 cells. 1 / 1
| 1

eidos
"PSMD7 knockdown also led to an increase in apoptosis ( sub-G1 peak ) in H1299 cells but not in A549 cells ( Figure 3C ) ."
PSMD7 affects GPW50
| 1
PSMD7 binds GPW50. 1 / 1
| 1

sparser
"On the other hand, the worst compressive strength result was obtained for the GPW50-P40 composite at 4.01 MPa."
PSMD7 affects GPW100
| 1
PSMD7 binds GPW100. 1 / 1
| 1

sparser
"Thus, the best values were achieved for GPW100-P40 (0.143 W/m°K), in which an enhancement of 42.8% was obtained relative to the reference plaster (0.250 W/m°K)."
PSMD7 affects G3CKS7
1 |
1 |

No evidence text available
PSMD7 affects G0 G1-phase
| 1
PSMD7 activates G0 G1-phase. 1 / 1
| 1

eidos
"Our results showed that knockdown of PSMD7 induced G0 / G1-phase arrest in both H1299 and A549 cells ."
PSMD7 affects G0 G1-phase cell cycle
| 1
PSMD7 activates G0 G1-phase cell cycle. 1 / 1
| 1

eidos
"A high PSMD7 level predicted poor overall survival ( OS ) and disease-free survival ( DFS ) in LUAD patients , and PSMD7 knockdown significantly reduced cell proliferation and induced G0 / G1-phase cell cycle arrest , cell senescence and apoptosis ."
PSMD7 affects Fibrinogen
| 1

sparser
"Interestingly, no significant difference inR h was observed for the GPRP-P40-I60 and GPSP-P40-I60 mixed micelles at all temperatures tested, even though an interaction between the GPRP-P40-I60 mixed micelles and fibrinogen was clearly observed for the turbidity assays within this temperature range."
PSMD7 affects FOXM1
| 1
PSMD7 inhibits FOXM1. 1 / 1
| 1

reach
"The presence of Rpn8 restricts this movement of α2 helix as well as that of the Ins-1 loop."
PSMD7 affects FKBP8
1 |
1 |

No evidence text available
PSMD7 affects FBXO6
1 |
1 |

No evidence text available
PSMD7 affects FBF1
1 |
1 |

No evidence text available
PSMD7 affects EWSR1
1 |
1 |

No evidence text available
PSMD7 affects EAF2
| 1
PSMD7 activates EAF2. 1 / 1
| 1

reach
"P39 (TR0423), P40 (18-599), P46 (CML504), and P50 (TR0582) contributed to higher yield related traits."
| 1
E3_Ub_ligase binds CUL3, PSMD7, and cul4. 1 / 1
| 1

sparser
"NAC1 is a unique POZ/BTB protein ( Cha et al., 1997; Korutla et al., 2002 ), and that binds to Cul3 and Cul4 E3 ubiquitin ligases, and Mov34, a protein in the 26S proteasome subunit ( Shen et al., 200[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
PSMD7 affects DNA Damage
| 1
| 1

reach
"PSMD7 promoted cell viability, apoptosis resistance, and DNA damage repair in GC cells upon cisplatin (DDP) treatment."
PSMD7 affects DLD
1 |
1 |

No evidence text available
PSMD7 affects DCTN1
1 |
1 |

No evidence text available
PSMD7 affects D1-K269R
| 1
PSMD7 binds D1-K269R. 1 / 1
| 1

reach
"Consistent with this notion, binding of D1-K269R and PSMD7 (a subunit of the proteasome cap) was reduced relative to that observed with wild-type cyclin D1."
PSMD7 affects Cell Line
| 1
| 1

eidos
"Knockdown of PSMD7 resulted in significant inhibition of cell proliferation in both cell lines ( Figure 3A ) ."
PSMD7 affects Cap
| 1
PSMD7 increases the amount of Cap. 1 / 1
| 1

reach
"The P40 promoter initiates the transcription of the Cap gene and produces two mRNAs by alternative splicing [XREF_BIBR]."
| PMC
PSMD7 affects CUL3
| 1
E3_Ub_ligase binds CUL3, PSMD7, and cul4. 1 / 1
| 1

sparser
"NAC1 is a unique POZ/BTB protein ( Cha et al., 1997; Korutla et al., 2002 ), and that binds to Cul3 and Cul4 E3 ubiquitin ligases, and Mov34, a protein in the 26S proteasome subunit ( Shen et al., 200[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
PSMD7 affects COX5B
1 |
1 |

No evidence text available
PSMD7 affects CNTRL
1 |
1 |

No evidence text available
PSMD7 affects CISD1
1 |
1 |

No evidence text available
PSMD7 affects CENPE
1 |
1 |

No evidence text available
PSMD7 affects CDIPT
| 1
| 1

sparser
"Comparison of the PI3K-C2α structure in this region with P40 phox or Grd19p, both of which bind 3-phosphorylated PIs, immediately reveals that the conserved basic residues involved in the specific interaction with the 3-phosphate group are missing in the PI3K-C2α PX domain."
PSMD7 affects CCND1
1 |
1 |

No evidence text available
PSMD7 affects CCDC92
1 |
1 |

No evidence text available
PSMD7 affects CASP3
| 1
PSMD7 inhibits CASP3. 1 / 1
| 1

reach
"PSMD7 knockdown raised caspase-3 activity compared with the control (P < 0.05), which was further confirmed by the increased cleavage of caspase-3 in shPSMD7 group."
PSMD7 affects BRCA1
1 |
1 |

No evidence text available
PSMD7 affects BLH9
| 1
| 1

sparser
"Among these genes, RpL14, RpS24, and Rpn8 are associated with heart phenotypes."
| 1

sparser
"Further, mild cognitive impairment has been associated with increased expression of P40 PHOX , P47 PHOX , and P67 PHOX in AD brains [ xref ]."
PSMD7 affects Ac34
| 1
PSMD7 binds Ac34. 1 / 1
| 1

reach
"Co-immunoprecipitation analysis of the interaction between Ac34 and Arp2/3 subunits revealed that Ac34 bound to P40, P34, and P20 of Sf9 cells."
PSMD7 affects ATXN7
1 |
1 |

No evidence text available
PSMD7 affects ATXN3
1 |
1 |

No evidence text available
PSMD7 affects APOH
| 1
PSMD7 activates APOH. 1 / 1
| 1

reach
"P addition alone increased enzyme activity, and P40 addition increased the ratio of BG to soil microbial biomass carbon (MBC), and (NAG + LAP):MBC activity ratio, thereby aggravating C restriction."
PSMD7 affects ANXA6
| 1
| 1

sparser
"To test this hypothesis, we used transgenic mice with astrocytic expression of a dominant-negative vesicle-associated membrane protein 2 ([gfap]dnVAMP2) to reduce exocytosis of thrombin inhibitors, modulating astrocytic regulation of paranodal loop attachment to induce nodal remodeling, under normal conditions and in adult mice maintained in darkness from P40-P70."
PSMD7 affects AKT
| 1
| 1

trips
"Immunoprecipitation experiments demonstrated direct binding between AKT and SRp40 with an increase in the amount of SRp40 bound to AKT upon TGFβ1 treatment."
PSMD7 affects AGPAT1
| 1
| 1

sparser
"Three groups of patients received inactivated IFN alpha (i-IFN alpha) associated with the immunomodulator P40 with HIV-1 antigens (groups B and C) or without (group A), and one group (D) was placebo."
PSMD7 affects ACTR2
1 |
1 |

No evidence text available
PSMD7 affects ABCF1
1 |
1 |

No evidence text available
PSMD7 affects AAV type-2
| 1
PSMD7 activates AAV type-2. 1 / 1
| 1

reach
"With the goal of using adeno associated viruses (AAV) as the gene-transfer vector for gene therapy of hemoglobinopathies, human beta-globin cDNA was ligated downstream from the P40 promoter of the AAV type-2 (AAV2) genome."

reach
"P40 phox binds to p47 phox and p67 phox in NOX1 and NOX2 NADPH oxidase complexes."
PSMD14 affects USP15
| 1
| 1

sparser
"For example, USP11 has been found to interact with USP4, USP7 and USP15; and PSMD7 interacts with USP15 and PSMD14 [ xref ]."
PSMB8 affects PSMD7
1 |
1 |

No evidence text available
PSMA8 affects PSMD7
1 |
1 |

No evidence text available
PRKN affects PSMD7
1 |
1 |

No evidence text available
PRF1 affects PSMD7
| 1
| 1

sparser
"To understand the local material flow behavior further, the time-averaged velocities of the analysed points for material flow i.e., points P1P40 during the refill FSSW are shown in xref ."
| PMC
PON1 affects PSMD7
| 1
| 1

sparser
"Superimposition of the RGD loop (residues K21-D30) and C-terminus (residues P40-K45) resulted in RMSD values of 0.162 Å and 0.581 Å, respectively ( xref D,E)."
POLDIP3 affects EIF3F
| 1
| 1

sparser
"We have demonstrated that CDK11 p46 interacts with the Mov34 domain of eIF3f in vitro and in vivo , and the interaction can be strengthened by the stimulation of apoptosis [ xref ]."
PHOX2B affects PSMD7
| 1

sparser
"Further, mild cognitive impairment has been associated with increased expression of P40 PHOX , P47 PHOX , and P67 PHOX in AD brains [ xref ]."
PHB affects Porins
| 1
Porins binds PHB and PSMD7. 1 / 1
| 1

sparser
"In addition, these authors also showed that increased susceptibility of Ae. aegypti to CHIKV mediated by S. odorifera , is due to interaction of the P40 protein of the bacterium with proteins prohibitin and porin present on the midgut of Ae. aegypti that immunosuppress the mosquito, thus accentuating the infection to CHIKV ( xref )."
PDXK affects PSMD7
| 1
PDXK activates PSMD7. 1 / 1
| 1

reach
"In KEGG, the upregulated DEPs were as follows: 1) NDUFS3, NDUFA13, NDUFAB1, NDUFA9, COX6C, COX4I1, COX5B, COX5A, ATP5PF, ATP5ME, ATP5PB, CYCS, and PDXK, which are related to electron transport chain (ETC) with immune responses; 2) CLTA, M6PR, and LGMN of lysosomal proteins to mediate an immune response; 3) NF-kB1 and proteasomes (PSMD7, PSMA5, and PSMD3); and 4) tropomycin 1 to 4 which may facilitate T-cell synaptic actin."
PB2 affects PSMD7
1 |
1 |

No evidence text available
PB1 affects PSMD7
1 |
1 |

No evidence text available
PALM affects PSMD7
| 1
PALM inhibits PSMD7. 1 / 1
| 1

reach
"It was found that acupuncture significantly suppressed the amplitude of P22 and P40, and that the tactile skin stimulation of the ulnar side of the palm significantly suppressed the amplitude of P22 and P40, but that the peak latencies were not affected."
PA affects PSMD7
1 |
1 |

No evidence text available
P78/83 affects PSMD7
| 1
PSMD7 binds P78/83. 1 / 1
| 1

reach
"In addition, co-immunoprecipitation assay demonstrated that P40 interacted with P78/83 only in virus infected cells, suggesting that actin polymerization induced by P78/83-Arp 2/3 complex during baculovirus infection was regulated by some unidentified virus factors."

reach
"Further investigations revealed that P9-1 could competitively bind to RPN8 with RPN7, thereby disrupting the assembly of 26S proteasome in L. striatellus and promoting the infection of RBSDV in insect vectors, and further affecting the transmission of the virus to rice by insect vectors."
P100 affects PSMD7
| 1
| 1

reach
"We were able to show that the recombinant P40 can also interact preferentially with P100, when compared to P26, which corresponds to the C-terminal portion of OTI-VIT-6."
Oprozomib affects PSMD7
1 |
1 |

No evidence text available
OFD1 affects PSMD7
1 |
1 |

No evidence text available
ODF1 affects PSMD7
1 |
1 |

No evidence text available
O41946 affects PSMD7
1 |
1 |

No evidence text available
Nα-acetyl affects PSMD7
| 1
MYL9 binds HEXIM2, PSMD7, and Nα-acetyl. 1 / 1
| 1

sparser
"The increased binding of PSMD7 and HEXIM2 to Nα-acetyl-MYL9 did not reproduce but the decreased binding of Cofilin-1 to Nα-methyl-MYL9 was reproducible ( xref )."
NTRK1 affects PSMD7
1 |
1 |

No evidence text available
NSC668394 affects PSMD7
1 |
NSC668394 decreases the amount of PSMD7. 1 / 1
1 |

No evidence text available
NSC305787 affects PSMD7
1 |
NSC305787 decreases the amount of PSMD7. 1 / 1
1 |

No evidence text available
NSC 689534 affects PSMD7
1 |
NSC 689534 increases the amount of PSMD7. 1 / 1
1 |

No evidence text available
NP_579894 affects PSMD7
1 |
PSMD7 binds NP_579894. 1 / 1
1 |

No evidence text available
NPHP1 affects PSMD7
1 |
1 |

No evidence text available
NOS2 affects PSMD7
1 |
1 |

No evidence text available
NMDAR affects PSMD7
| 1
NMDAR activates PSMD7. 1 / 1
| 1

reach
"We have employed the calyx of Held terminal with its target, the principal neuron of the medial nucleus of the trapezoid body (MNTB), to examine the NMDAR mediated EPSC during synapse maturation from P10 to P40."
NFKB2 affects PSMD7
| 1
| 1

sparser
"We were able to show that the recombinant P40 can also interact preferentially with P100, when compared to P26, which corresponds to the C-terminal portion of OTI-VIT-6."
NFE2L2 affects PSMD7
1 |
NFE2L2 decreases the amount of PSMD7. 1 / 1
1 |

No evidence text available
NFE2L1 affects PSMD7
1 |
NFE2L1 decreases the amount of PSMD7. 1 / 1
1 |

No evidence text available
NDUFV1 affects PSMD7
1 |
1 |

No evidence text available
NDUFS3 affects PSMD7
| 1
NDUFS3 activates PSMD7. 1 / 1
| 1

reach
"In KEGG, the upregulated DEPs were as follows: 1) NDUFS3, NDUFA13, NDUFAB1, NDUFA9, COX6C, COX4I1, COX5B, COX5A, ATP5PF, ATP5ME, ATP5PB, CYCS, and PDXK, which are related to electron transport chain (ETC) with immune responses; 2) CLTA, M6PR, and LGMN of lysosomal proteins to mediate an immune response; 3) NF-kB1 and proteasomes (PSMD7, PSMA5, and PSMD3); and 4) tropomycin 1 to 4 which may facilitate T-cell synaptic actin."
NDUFA13 affects PSMD7
| 1
NDUFA13 activates PSMD7. 1 / 1
| 1

reach
"In KEGG, the upregulated DEPs were as follows: 1) NDUFS3, NDUFA13, NDUFAB1, NDUFA9, COX6C, COX4I1, COX5B, COX5A, ATP5PF, ATP5ME, ATP5PB, CYCS, and PDXK, which are related to electron transport chain (ETC) with immune responses; 2) CLTA, M6PR, and LGMN of lysosomal proteins to mediate an immune response; 3) NF-kB1 and proteasomes (PSMD7, PSMA5, and PSMD3); and 4) tropomycin 1 to 4 which may facilitate T-cell synaptic actin."
NCF2 affects PSMD7
| 1

sparser
"Further, mild cognitive impairment has been associated with increased expression of P40 PHOX , P47 PHOX , and P67 PHOX in AD brains [ xref ]."
NACC1 affects PSMD7
1 |
1 |

No evidence text available
NA affects PSMD7
1 |
1 |

No evidence text available

reach
"MG132 treatment significantly reversed the effect of PSMD7 silencing on RAD23B levels in AGS cells (P < 0.05, Supplementary Figure 7)."
Mice affects PSMD7
| 1
Mutated Mice activates PSMD7. 1 / 1
| 1

reach
"Mutant mice show reduced nerve conduction velocity at P20 and P40 and decreased compound muscle action potential (CMAP) amplitude at P40 (Fig. 1h), in addition to reduced motor performance in the rotarod test at P20 (Supplementary Fig. 1f)."
MYL9 affects PSMD7
| 1
MYL9 binds HEXIM2, PSMD7, and Nα-acetyl. 1 / 1
| 1

sparser
"The increased binding of PSMD7 and HEXIM2 to Nα-acetyl-MYL9 did not reproduce but the decreased binding of Cofilin-1 to Nα-methyl-MYL9 was reproducible ( xref )."
MTCH1 affects PSMD7
1 |
1 |

No evidence text available
MT-ATP6 affects RPN8
| 1
| 1

sparser
"Among these genes, RpL14, RpS24, and Rpn8 are associated with heart phenotypes."
MRPS16 affects PSMD7
1 |
1 |

No evidence text available
MMEL1 affects PSMD7
| 1
| 1

sparser
"Interestingly, it has been shown that clinical neurophysiological parameters obtained from the lower extremities, like the P40-SEP, H-reflex and nociceptive RIII reflex were lowered in the “on” condition of the SCS stimulator."
MME affects PSMD7
| 1
| 1

sparser
"The polypeptides interacting with P40 were further characterized using MALDI-TOF/TOF analysis."
MID1 affects PSMD7
1 |
1 |

No evidence text available
MED4 affects PSMD7
1 |
1 |

No evidence text available
MED23 affects PSMD7
1 |
1 |

No evidence text available
MCFD2 affects PSMD7
1 |
1 |

No evidence text available
MAPT affects PSMD7
1 |
MAPT decreases the amount of PSMD7. 1 / 1
1 |

"Impairment of 26S proteasome induced by tau can be prevented early in disease through activation of cAMP-PKA signaling, and raising the levels of cAMP with rolipram may enhance tau degradation (Myeku et al. 2016)"
MAFG affects PSMD7
1 |
MAFG decreases the amount of PSMD7. 1 / 1
1 |

No evidence text available
LV5-P40 affects PSMD7
| 1
LV5-P40 activates PSMD7. 1 / 1
| 1

reach
"We used lentivirus LV5-P40 overexpressing P40 to infect primary hippocampal neurons and characterized the interactome of P40 with co-immunoprecipitation (Co-IP) followed by mass spectrometry (MS) analysis."
LMP2 affects PSMD7
1 |
1 |

No evidence text available
Ketolides affects PSMD7
1 |
Ketolides decreases the amount of PSMD7. 1 / 1
1 |

No evidence text available

No evidence text available
KCMF1 affects PSMD7
1 |
1 |

No evidence text available
Intra-PAG WIN55212 affects PSMD7
| 1
Intra-PAG WIN55212 activates PSMD7. 1 / 1
| 1

reach
"Intra-PAG WIN55212 significantly reduced spinal reflex excitability (supplemental Fig. 2C, available online at http://links.lww.com/PAIN/A471) and increased mechanical withdrawal thresholds (supplemental Fig. 2D, available online at http://links.lww.com/PAIN/A471) in both P21 and P40 rats compared with vehicle controls."
INTU affects PSMD7
1 |
1 |

No evidence text available
ID1 affects PSMD7
| 1
| 1

sparser
"In the CC at P40, ID was associated with reduced peak amplitudes of compound action potentials specific to myelinated axons, in which diameters were reduced by ∼20% compared with Fe+ controls."
HUWE1 affects PSMD7
1 |
1 |

No evidence text available
HU210 affects PSMD7
| 1
HU210 activates PSMD7. 1 / 1
| 1

reach
"Intra-PAG HU210-induced antinociceptive effects were stronger in P21 and P40 animals compared with P10 (Figs."
HTR1A affects TRIM21
| 1
| 1

sparser
"RNA-seq analysis and coimmunoprecipitation assays indicate that HTR1A interacts with TRIM21 and PSMD7 to inhibit the degradation of TβRII through the ubiquitin-proteasome pathway, thereby inhibiting the transforming growth factor-β (TGF-β) canonical and noncanonical pathway."
HSD17B10 affects PSMD7
1 |

No evidence text available
HNSCC affects PSMD7
| 1
PSMD7 binds HNSCC. 1 / 1
| 1

reach
"Then, we focus on the association between PSMD7 and HNSCC."
HIV1gp8 affects PSMD7
1 |
PSMD7 binds HIV1gp8. 1 / 1
1 |

No evidence text available
HIV1gp4 affects PSMD7
1 |
PSMD7 binds HIV1gp4. 1 / 1
1 |

No evidence text available
HEXIM2 affects PSMD7
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MYL9 binds HEXIM2, PSMD7, and Nα-acetyl. 1 / 1
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sparser
"The increased binding of PSMD7 and HEXIM2 to Nα-acetyl-MYL9 did not reproduce but the decreased binding of Cofilin-1 to Nα-methyl-MYL9 was reproducible ( xref )."
HCFC1 affects PSMD7
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No evidence text available
GPW50 affects PSMD7
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PSMD7 binds GPW50. 1 / 1
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sparser
"On the other hand, the worst compressive strength result was obtained for the GPW50-P40 composite at 4.01 MPa."
GPW100 affects PSMD7
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PSMD7 binds GPW100. 1 / 1
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sparser
"Thus, the best values were achieved for GPW100-P40 (0.143 W/m°K), in which an enhancement of 42.8% was obtained relative to the reference plaster (0.250 W/m°K)."
GC affects PSMD7
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GC activates PSMD7. 1 / 1
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reach
"DBP of patients in Group NS was elevated significantly from P5 to P40 (P < 0.001) as compared to Group M and from P5 to P30 as compared to Group C. On comparing patients in Group M and Group C, DBP was significantly lower in M Group from P5 to P40 [XREF_TABLE]."
G3CKS7 affects PSMD7
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No evidence text available
Fibrinogen affects PSMD7
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sparser
"Interestingly, no significant difference inR h was observed for the GPRP-P40-I60 and GPSP-P40-I60 mixed micelles at all temperatures tested, even though an interaction between the GPRP-P40-I60 mixed micelles and fibrinogen was clearly observed for the turbidity assays within this temperature range."
FKBP8 affects PSMD7
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No evidence text available
FBXO6 affects PSMD7
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No evidence text available
FBF1 affects PSMD7
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No evidence text available
EWSR1 affects PSMD7
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No evidence text available
EIF3F affects RPS6KB1
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sparser
"Particularly, the inactive hypophosphorylated form of S6K1 physically associates with the Mov34 domain of eIF3f [ xref ]."
EIF3F affects POLDIP3, and PSMD7
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sparser
"We have demonstrated that CDK11 p46 interacts with the Mov34 domain of eIF3f in vitro and in vivo , and the interaction can be strengthened by the stimulation of apoptosis [ xref ]."

sparser
"These observations were supported by a series of analyses that demonstrated interactions between multiple α-HPV E6 oncoproteins and PSMA3, PSMC2, PSMC3, PSMD1, PSMD2, PSMD3, PSMD14, PSMD11, PSMD7, PSMC4, PSMD13, PSMD6, PSMD8, PSMB7, PSMB9 and PSME4 proteasomal subunits, while a panel of β-HPV E6 oncoproteins interacted only with a few proteasomal subunits, including PSMA3, PSMC2, PSMD1, PSMD2, PSMD3, PSMD11, and PSMD13 [ xref , xref , xref ]."
E3_Ub_ligase affects cul4
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E3_Ub_ligase binds CUL3, PSMD7, and cul4. 1 / 1
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sparser
"NAC1 is a unique POZ/BTB protein ( Cha et al., 1997; Korutla et al., 2002 ), and that binds to Cul3 and Cul4 E3 ubiquitin ligases, and Mov34, a protein in the 26S proteasome subunit ( Shen et al., 200[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
DLD affects PSMD7
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No evidence text available
DCTN1 affects PSMD7
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No evidence text available
D1-K269R affects PSMD7
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PSMD7 binds D1-K269R. 1 / 1
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reach
"Consistent with this notion, binding of D1-K269R and PSMD7 (a subunit of the proteasome cap) was reduced relative to that observed with wild-type cyclin D1."

sparser
"The IHC results showed CK-pan (+), CK7 (-), CK20 (-), Villin (-), Ki-67 (70%+), P63 (+), P40 (+), Hepatocyte (-), Glypican-3 (-), PSA (-), PSAP (-), D2-40 (-), CR (-), and RCC (-)."
Carfilzomib affects PSMD7
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No evidence text available
CYCS affects PSMD7
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CYCS activates PSMD7. 1 / 1
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reach
"In KEGG, the upregulated DEPs were as follows: 1) NDUFS3, NDUFA13, NDUFAB1, NDUFA9, COX6C, COX4I1, COX5B, COX5A, ATP5PF, ATP5ME, ATP5PB, CYCS, and PDXK, which are related to electron transport chain (ETC) with immune responses; 2) CLTA, M6PR, and LGMN of lysosomal proteins to mediate an immune response; 3) NF-kB1 and proteasomes (PSMD7, PSMA5, and PSMD3); and 4) tropomycin 1 to 4 which may facilitate T-cell synaptic actin."
CYBB affects NADPH_oxidase, NCF1, NCF2, NOX1, and PSMD7
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sparser
"P40 phox binds to p47 phox and p67 phox in NOX1 and NOX2 NADPH oxidase complexes."
CUL3 affects cul4
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E3_Ub_ligase binds CUL3, PSMD7, and cul4. 1 / 1
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sparser
"NAC1 is a unique POZ/BTB protein ( Cha et al., 1997; Korutla et al., 2002 ), and that binds to Cul3 and Cul4 E3 ubiquitin ligases, and Mov34, a protein in the 26S proteasome subunit ( Shen et al., 200[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
COX5B affects PSMD7
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No evidence text available
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sparser
"HECT Homologous to the E6AP Carboxyl Terminus RING Really Interesting New Gene JAMM JAB1/MPR/Mov34 Metalloprotease MINDY Motif Interacting with Ubiquitin-Containing Novel DUB Family CoA Reductase Degradation Protein 1 ERAD Endoplasmic Reticulum Associated Protein Degradation POZ Pox Virus and Zinc Finger Protein SPOP Speckle-Type POZ Protein APC/C Anaphase-Promoting Complex/Cyclosome CDK Cyclin Dependent Kinase c-Cbl Casitas B-Cell Lymphoma Cbl-b Casitas B-Lineage Lymphoma Proto-Oncogene-B STAT Signal Transducer and Activator of Transcription Protein Like Factor CMTM6 CKLF-Like Marvel Transmembrane Domain Containing Family Member 6 HAUSP Herpesvirus Associated Ubiquitin Specific Protease HectH9 Homologous to E6AP Carboxyl Terminus Homologous Protein 9 HUWE1 HECT, UBA and WWE Domain Containing E3 Ubiquitin Protein Ligase 1 MCPIP1 Monocyte Chemoattractant Protein Induced Protein 1 SMURF SMAD Specific E3 Ubiquitin Protein Ligase Domain Present in Ub Specific Proteases MERS-CoV Middle East Respiratory Syndrome Coronavirus CCHFV Crimean-Congo Hemorrhagic Fever Virus"
CNTRL affects PSMD7
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No evidence text available
CNR2 affects PSMD7
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CNR2 inhibits PSMD7. 1 / 1
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reach
"CB1/CB2 receptors in the brainstem nuclei inhibit nociceptive reflex in both P21 and P40 rodents."
CNR1 affects PSMD7
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CNR1 inhibits PSMD7. 1 / 1
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reach
"CB1/CB2 receptors in the brainstem nuclei inhibit nociceptive reflex in both P21 and P40 rodents."
CISD1 affects PSMD7
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No evidence text available
CENPE affects PSMD7
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No evidence text available
CDIPT affects PSMD7
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sparser
"Comparison of the PI3K-C2α structure in this region with P40 phox or Grd19p, both of which bind 3-phosphorylated PIs, immediately reveals that the conserved basic residues involved in the specific interaction with the 3-phosphate group are missing in the PI3K-C2α PX domain."
CCND1 affects PSMD7
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No evidence text available
CCDC92 affects PSMD7
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No evidence text available
CBX6 affects DPYD, FOXF1, MSI1, PLOD2, POLD3, PSMD7, RPS24, TLE3, and USP5
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sparser
"Twenty sites were differentially methylated in the obese individuals compared to the normal-weight controls, 15 sites associated with the genes CERCAM, DPYD, ZNF35, ZNF362, CBX6, FOXF1, PSMD7, PRRC2C,[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
CB2 receptors affects PSMD7
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CB2 receptors inhibits PSMD7. 1 / 1
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reach
"CB1/CB2 receptors in the brainstem nuclei inhibit nociceptive reflex in both P21 and P40 rodents."
BRCA1 affects PSMD7
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No evidence text available
BPNT1 affects PSMD7
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BPNT1 activates PSMD7. 1 / 1
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reach
"Western blotting analyses confirmed that the 157 nucleotides at the 3 ' end of the pip gene, when inserted at the 5 ' end of the P40 lipoprotein gene, promote complementation of the P40 minus mutant."
BLH9 affects RPN8
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sparser
"Among these genes, RpL14, RpS24, and Rpn8 are associated with heart phenotypes."
BACH1 affects PSMD7
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BACH1 decreases the amount of PSMD7. 1 / 1
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No evidence text available
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Aroclor 1254 decreases the amount of PSMD7. 1 / 1
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No evidence text available
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sparser
"Further, mild cognitive impairment has been associated with increased expression of P40 PHOX , P47 PHOX , and P67 PHOX in AD brains [ xref ]."
Ac34 affects PSMD7
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PSMD7 binds Ac34. 1 / 1
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reach
"Co-immunoprecipitation analysis of the interaction between Ac34 and Arp2/3 subunits revealed that Ac34 bound to P40, P34, and P20 of Sf9 cells."
ATXN7 affects PSMD7
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No evidence text available
ATXN3 affects PSMD7
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No evidence text available
ATF4 affects PSMD7
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ATF4 decreases the amount of PSMD7. 1 / 1
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No evidence text available
ANXA6 affects PSMD7
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sparser
"To test this hypothesis, we used transgenic mice with astrocytic expression of a dominant-negative vesicle-associated membrane protein 2 ([gfap]dnVAMP2) to reduce exocytosis of thrombin inhibitors, modulating astrocytic regulation of paranodal loop attachment to induce nodal remodeling, under normal conditions and in adult mice maintained in darkness from P40-P70."
AKT affects PSMD7
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trips
"Immunoprecipitation experiments demonstrated direct binding between AKT and SRp40 with an increase in the amount of SRp40 bound to AKT upon TGFβ1 treatment."
AGPAT1 affects PSMD7
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sparser
"Three groups of patients received inactivated IFN alpha (i-IFN alpha) associated with the immunomodulator P40 with HIV-1 antigens (groups B and C) or without (group A), and one group (D) was placebo."
ACTR2 affects PSMD7
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No evidence text available
ABCF1 affects PSMD7
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No evidence text available
7,12-dimethyltetraphene decreases the amount of PSMD7. 1 / 1
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No evidence text available
4-hydroxyphenyl retinamide increases the amount of PSMD7. 1 / 1
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No evidence text available

reach
"P40 phox binds to p47 phox and p67 phox in NOX1 and NOX2 NADPH oxidase complexes."
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No evidence text available
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No evidence text available
1H-pyrazole affects PSMD7
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1H-pyrazole increases the amount of PSMD7. 1 / 1
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No evidence text available
17alpha-ethynylestradiol increases the amount of PSMD7. 1 / 1
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No evidence text available
1,2-dithiol-3-thione increases the amount of PSMD7. 1 / 1
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No evidence text available