IndraLab

Statements

P38 binds PSMD7. 21 / 21
| 21
sparser
"Moreover, we photo-tagged PV-expressing interneurons in the mPFC of PV-cre mice after viral transfection with cre-dependent ChR2(ET/TC) to confirm that FS units at P23–P26 and P38–P40 correspond to PV interneurons."
33675685
sparser
"The density of SOM-positive neurons was reduced slightly in ES mice at P11–P12 and P38–P40, whereas the density of PV-positive neurons was increased significantly at P38–P40 ( xref B)."
33675685
sparser
"In contrast, evoked activity during acute ramp light stimulation was reduced for RS and FS units in ES mice at P38–P40 but normal earlier during development ( xref G and xref C)."
33675685
sparser
"A comparison across age revealed that the dendritic length increased with age for control (linear mixed effect model [LMEM]; P11–P12 to P23–P25, ∗∗ p = 0.002; P11–P12 to P38–P40, ∗∗∗ p = 0.0002), but not for ES mice (LMEM; P11–P12 to P23–P25, p = 0.79; P11–P12 to P38–P40, p = 0.07)."
33675685
sparser
"This second peak was reduced significantly in ES mice at P23–P26 and P38–P40."
33675685
sparser
"In contrast to transient ES at P7–P11, oES only mildly affected the peak frequency, but not the peak strength, of light-induced fast oscillatory activity or multi-unit activity (MUA) at P38–P40 ( xref E and 6F)."
33675685
sparser
"The material outside the shoulder outer periphery remained unaffected throughout the process, see points P8–P10, P18–P20, P29–P30, and P38–P40."
| PMC
sparser
"For the other areas of material outside the shoulder outer periphery the material movement is negligible, see points P8–P10, P19–P20, P29–P30, and P38–P40."
| PMC
sparser
"Similar to network oscillations, the strength and frequency of the rhythmicity of neuronal firing increased with age, but the magnitude of the increase was lower for ES mice, reaching significance at P38–P40 ( xref C)."
33675685
sparser
"However, at P38–P40, the magnitude of light-induced gamma activity was significantly smaller in ES mice compared with controls."
33675685
sparser
"In-depth morphological analysis showed increased dendritic arborization of PV-positive neurons in the L2/3 of the mPFC of P38–P40 ES mice ( xref C–8E)."
33675685
sparser
"Decreased gamma synchrony and reduced activation versus inactivation in P38–P40 ES mice suggest that the transient increase in prefrontal activity at neonatal age causes long-term alterations of the balance between excitation and inhibition in the prefrontal circuitry."
33675685
sparser
"The spontaneous firing rate of RS units is altered in ES mice at P23–P26 and P38–P40 compared with controls, whereas no changes were detected for FS units ( xref F and xref B)."
33675685
sparser
"As reported for stimulation at P7–P11, oES did not affect task non-related spontaneous activity in the mPFC at P38–P40 ( xref D)."
33675685
sparser
"Both MAGL and FAAH activity and local 2-AG and AEA levels were measured by activity-based protein profiling (ABPP) and LC-MS/MS, respectively, in rat meninges obtained from hemiskulls of P38-P40 Wistar rats and human meninges from elderly patients undergoing non-migraine related neurosurgery."
37038131
sparser
"Hippocampal activity was similar in control and ES mice at P38–P40."
33675685
sparser
"To test this hypothesis, we recorded prefrontal activity of control and ES mice during a social preference task when they could navigate freely in a mobile home cage at P38–P40 ( xref E)."
33675685
sparser
"Acute light stimulation (473 nm, 3 s) of the intermediate HP at P38–P40 induced oscillatory activity in the HP that boosted gamma activity in the mPFC of control but not ES mice ( xref F–5H)."
33675685
sparser
"Acute light stimulation (ramp, 473 nm, 3 s) triggered fast rhythmic activity with peak frequencies increasing from 15–20 Hz (beta frequency range) at P11–P12 to 50–60 Hz (gamma frequency range) at P23–P26 and P38–P40 in the mPFC of control and ES mice ( xref A), in line with the recently described acceleration of fast frequency oscillations during prefrontal development ( xref )."
33675685
sparser
"Coherence between L2/3 and L5/6 of the stimulated hemisphere and coherence between L2/3 across hemispheres was reduced in ES mice at P38–P40 but was normal at a younger age ( xref D and S4E)."
33675685
sparser
"The ratio of activated versus inactivated neurons per mouse was similar across groups at P11–P12 and P23–P26 but reduced significantly in ES mice at P38–P40 compared with controls."
33675685