IndraLab

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PSMD7 activates cell population proliferation. 12 / 12
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"Similar with the findings, Shi et al. has reported that knockdown of PSMD7 induced ESCC apoptosis via a caspase-3 dependent pathway and decreased cells proliferation [XREF_BIBR]."
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"A high PSMD7 level predicted poor overall survival (OS) and disease-free survival (DFS) in LUAD patients, and PSMD7 knockdown significantly reduced cell proliferation and induced G0/G1-phase cell cycle arrest, cell senescence and apoptosis."
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"PSMD7 promotes the proliferation, migration, and invasion of GC cells."
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"MTT and EdU assays consistently demonstrated that PSMD7 knockdown reduced AGS cell proliferation (P < 0.05, Figures 2B and 2C)."
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"PSMD7 was identified as an oncogene in ESCC, and knockdown of PSMD7 induced proliferation inhibition, apoptosis, and mechanistic target of rapamycin (mTOR)/p70S6K pathway inactivation18."
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"A high PSMD7 level predicted poor overall survival ( OS ) and disease-free survival ( DFS ) in LUAD patients , and PSMD7 knockdown significantly reduced cell proliferation and induced G0 / G1-phase cell cycle arrest , cell senescence and apoptosis ."
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"Furthermore, knockdown of PSMD7 reduced proliferation and induced cell cycle arrest, senescence and apoptosis by regulating cell cycle proteins and the p53 pathway in tumor cells."
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"Studies have demonstrated that PSMD7 silencing induces proliferation inhibition and apoptosis of ESCC cells, and results in cell cycle arrest, cell senescence, and apoptosis in breast cancer cells18, 19."
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"In conclusion, PSMD7 knockdown inhibits proliferation and induces apoptosis in ESCC cells."
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"Deubiquitinase PSMD7 promotes the proliferation, invasion, and cisplatin resistance of gastric cancer cells by stabilizing RAD23B."
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"PSMD7 knockdown inhibits proliferation and induces apoptosis in ESCC cell line."
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"Functionally, we found that PSMD7 knockdown consistently suppressed the proliferation, migration, and invasion of AGS and SGC-7901 cells."
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