IndraLab

Statements

PSMD7 inhibits cell cycle. 8 / 8
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"A high PSMD7 level predicted poor overall survival (OS) and disease-free survival (DFS) in LUAD patients, and PSMD7 knockdown significantly reduced cell proliferation and induced G0/G1-phase cell cycle arrest, cell senescence and apoptosis."
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"PSMD7 knockdown induced cell cycle arrest, senescence, and apoptosis and suppressed LUAD tumor growth in a xenograft mouse model."
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"Importantly, PSMD7 knockdown induced cell cycle arrest in the G0/G1 phase, leading to cell senescence and apoptosis."
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"These findings indicate that P40 anthocyanin extract inhibits cancer cell growth by inducing cell cycle arrest rather than through a cytotoxic effect."
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"Down-regulated PSMD7 inhibits the expression of key cell cycle related proteins and promotes the stability of p21 and p27 in breast cancer cells [XREF_BIBR]."
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"PSMD7 knockdown induces cell cycle arrest, senescence and apoptosis in LUAD cells."
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"In conclusion, PSMD7 knockdown induces cell cycle arrest, senescence and apoptosis in LUAD cells."
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"Furthermore, knockdown of PSMD7 reduced proliferation and induced cell cycle arrest, senescence and apoptosis by regulating cell cycle proteins and the p53 pathway in tumor cells."
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