IndraLab

Statements

PSMD7 inhibits TP53. 4 / 4
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"Depletion of PSMD7 increased p53 levels and induced p21 and puma expression in a p53-dependent manner ."
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"PSMD7 downregulation suppresses lung cancer progression by regulating the p53 pathway."
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"PSMD7 knockout was shown to induce cell cycle arrest in G0/G1 phase, leading to cell senescence and apoptosis or inhibit lung cancer progression by modulating the p53 pathway [45]."
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"Furthermore, knockdown of PSMD7 reduced proliferation and induced cell cycle arrest, senescence and apoptosis by regulating cell cycle proteins and the p53 pathway in tumor cells."
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