IndraLab

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"Similar with the findings, Shi et al. has reported that knockdown of PSMD7 induced ESCC apoptosis via a caspase-3 dependent pathway and decreased cells proliferation [XREF_BIBR]."
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"Foxp3 interacts to the PSMD7 promoter and stimulates PSMD7 expression, both of which are up-regulated in gastric cancer tissues, boosting GC cell proliferation and blocking apoptosis (70)."
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"A high PSMD7 level predicted poor overall survival ( OS ) and disease-free survival ( DFS ) in LUAD patients , and PSMD7 knockdown significantly reduced cell proliferation and induced G0 / G1-phase cell cycle arrest , cell senescence and apoptosis ."
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"Knockdown of PSMD7 induces apoptosis and inhibits tumorigenesis in esophageal squamous cell carcinoma 22 ."
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"PSMD7 knockdown induced cell cycle arrest , senescence , and apoptosis and suppressed LUAD tumor growth in a xenograft mouse model ."
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"PSMD7 knockdown induces cell cycle arrest , senescence and apoptosis in LUAD cells A previous study 22 demonstrated that downregulation of PSMD7 led to decreased cell proliferation and increased apoptosis in esophageal squamous cell carcinoma ."
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"PSMD7 knockdown also led to an increase in apoptosis ( sub-G1 peak ) in H1299 cells but not in A549 cells ( Figure 3C ) ."
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"In conclusion , PSMD7 knockdown induces cell cycle arrest , senescence and apoptosis in LUAD cells ."
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"In LUAD patients, an elevated level of PSMD7 was linked to the unfavorable OS and disease-free survival, and PSMD7 silencing considerably attenuated the proliferative ability of cells and triggered the G0/G1-phase cell cycle arrest, cell senescence, and apoptosis [37]."
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"A high PSMD7 level predicted poor overall survival (OS) and disease-free survival (DFS) in LUAD patients, and PSMD7 knockdown significantly reduced cell proliferation and induced G0/G1-phase cell cycle arrest, cell senescence and apoptosis."
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"PSMD7 knockdown induced cell cycle arrest, senescence, and apoptosis and suppressed LUAD tumor growth in a xenograft mouse model."
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"PSMD7 knockdown induces cell cycle arrest, senescence and apoptosis in LUAD cells."
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"PSMD7 knockdown inhibits proliferation and induces apoptosis in ESCC cell line."
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"Knockdown of PSMD7 induces cell cycle arrest , senescence , and apoptosis by regulating cell cycle proteins and the p53 pathway in lung cancer cells ."
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"In conclusion, PSMD7 knockdown induces cell cycle arrest, senescence and apoptosis in LUAD cells."
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"Results showed that inhibition of PSMD7 in EC9706 cells caused cell apoptosis with significantly increased numbers of early apoptosis cells and late apoptosis cells (P < 0.05), but made no difference on cell cycle distribution (P> 0.05)."
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"In conclusion, PSMD7 knockdown inhibits proliferation and induces apoptosis in ESCC cells."
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"Furthermore, knockdown of PSMD7 reduced proliferation and induced cell cycle arrest, senescence and apoptosis by regulating cell cycle proteins and the p53 pathway in tumor cells."
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"It is interesting that we, at the first time, reported that PSMD7 knockdown resulted in decreased proliferation and enhanced apoptosis in ESCC cell lines."
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"These data provided strong evidences that PSMD7 impairment induced apoptosis of ESCC cell lines."
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"In ESCC xenografts bearing mice with repression of PSMD7, we also proved that invivo ability of PSMD7 inhibition suppresses tumor growth and induces apoptosis."
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