IndraLab

Statements

PSMD7 increases the amount of MTOR. 2 / 2
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"Inhibition of PSMD7 not only reduced the expression of mTOR and p70S6K, but also decreased the expression of p-mTOR Ser2448 and p-p70S6K Thr421 and Ser424, whereas the augmented expression of phosphorylation of mTOR and p70S6K was detected after PSMD7 overexpression in Het-1A cells."
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"Furthermore, reduced expression of PSMD7 leads to reduced mTOR level and activity, and perturbation of mTOR activity has been demonstrated to impact the rate of epigenetic aging [71]."
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