"Additionally, compared with the blank and the NC groups, the LINC00968 vector and si-WNT2 groups had decreased levels of beta-catenin, GSK3beta and Vimentin, downregulated phosphorylation levels of beta-catenin and GSK3beta, and elevated level of E-cadherin (all p < 0.05)."
"The expression of Wnt7b and beta-catenin in radial arteries was higher in end stage renal disease than in control group, and IS increased Wnt7b and beta-catenin expression in HASMCs as early as 3days after stimulation."
"We demonstrate that overexpression of membrane tethered beta-catenin elevates the level of free endogenous beta-catenin, which subsequently accumulates in nuclei."
"Consequently, beta-catenin transcription and translation was down-regulated, decreasing beta-catenin levels in the cytoplasm, and ultimately inhibiting the Wnt signaling pathway."
"We next investigated the possibility that increased levels of nuclear beta-catenin in the mutant developing cerebral cortex enhance the transcription of Wnt and beta-catenin target genes."
"Real-time PCR and Western blot assay at 48 h after infection showed that CTNNB1 knockdown in A-498 cells significantly decreased the mRNA and protein levels of CTNNB1 (XREF_FIG), whereas overexpression of CTNNB1 in 786-O (XREF_FIG) and ACHN cells (XREF_SUPPLEMENTARY) significantly increased the mRNA and protein levels of CTNNB1."
"The results showed that overexpression of beta-catenin increased beta-catenin level (XREF_FIG), and RNAi decreased beta-catenin expression (XREF_FIG)."
"HONE1 hybrid cells with infected beta-catenin shRNA have reduced expression of beta-catenin and representative results from various passages of cell populations after infection of shRNA plasmids are shown in the bottom panel, Figure XREF_FIG A. beta-catenin expression was reduced by approximately 54%, 97%, 70%, and 79% in MCH4.5 and MCH4.6 cell lines at different passage levels after infection."
"Bandapalli et al. [XREF_BIBR] reported that overexpression of beta-catenin increases nuclear level of beta-catenin and carcinogenesis including metastasis."
"However there were increased levels of p-beta-Catenin and decreased levels of activated-beta-Catenin in old HMDSCs."