IndraLab

Statements


Phosphorylated CTNNB1 increases the amount of CTNNB1. 3 / 3
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"37 Mutations in the beta-catenin phosphorylation region can activate beta-catenin signaling by upholding cellular beta-catenin levels."

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"Phosphorylation-mediated ubiquitination of β-catenin by β-TrCP and induced proteasomal degradation resulted in a low level of β-catenin in the cytoplasm."

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"MP has been shown to up-regulate the expression and activation of the beta-catenin signaling pathway, including low-density lipoprotein receptor related protein-6 (LRP) pho sphorylation, beta-catenin, and glycogen synthase kinase-3beta (GSK) phosphorylation (XREF_FIG) [XREF_BIBR]."