IndraLab

Statements

ZEB1 binds USP43. 6 / 6

| 1 5

sparser

"In this study, Co-immunoprecipitation (Co-IP) was employed to study the potential interaction between USP43 protein and ZEB1 protein."

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"ZEB1 can directly interact with USP43 in cellular."

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sparser

"ZEB1 can directly interact with USP43 in cellular."

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sparser

"Figure xref F showed that USP43 protein could interact with ZEB1 protein."

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sparser

"Figure xref F and xref G had further identified the interaction between USP43 protein and ZEB1 protein."

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sparser

"Moreover, we have examined the potential interaction between USP43 protein and ZEB1 protein in cellular."

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USP43 activates ZEB1.

| 5

USP43 activates ZEB1. 5 / 5

| 5

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"USP43 directly regulates ZEB1 protein, mediating proliferation and metastasis of colorectal cancer."

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"The results suggested that USP43 knockdown treated SW480 cells could significantly promote the degradation of the remaining ZEB1 protein in cells compared to that normal SW480 cells (P < 0.01)."

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"Figure XREF_FIG K and 5L suggested that USP43 overexpression in DLD1 cells could significantly promote the remaining ZEB1 protein in cells compared to that normal DLD1 cells (P < 0.01)."

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reach

"Meanwhile, USP43 knockdown treated SW480 cells could significantly decrease the remaining ZEB1 protein in cells compared to that normal SW480 cells (P < 0.01)."

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"Meanwhile, USP43 overexpression treated DLD1 cells could significantly decrease the degradation of the remaining ZEB1 protein in cells compared to that normal DLD1 cells (P < 0.01)."

33391437

USP43 deubiquitinates ZEB1.

| 2

USP43 deubiquitinates ZEB1. 2 / 2

| 2

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"USP43 could promote cell proliferation, invasion, and migration in colorectal cancer by regulating ZEB1 ubiquitylation degradation."

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"Meanwhile, USP43 can deubiquitinate and stabilize the ZEB1 protein, which plays an important role in the function of colorectal cancer."

33391437

USP43 decreases the amount of ZEB1.

| 1

USP43 decreases the amount of ZEB1. 1 / 1

| 1

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"Moreover, USP43 can reduce ZEB1 protein expression without affecting its transcription."

33391437

USP43 affects cell population proliferation

| 1 8

USP43 activates cell population proliferation. 9 / 9

| 1 8

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"USP43 knockdown in SW480 cells could significantly reduce cell proliferation."

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eidos

"USP43 could promote cell proliferation , invasion , and migration in colorectal cancer by regulating ZEB1 ubiquitylation degradation ."

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reach

"However, USP43 overexpression in DLD1 cells could significantly promote cell proliferation compared with those in vector treated DLD1 cells on days 2, 3, 4, 5 (P < 0.05)."

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"USP43 could promote the proliferation, migration, and invasion of colorectal cancer."

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reach

"USP43 overexpression promoted PANC-1 cell proliferation ( P = 0.0018), but USP43 knockdown decreased PANC02 cell proliferation ( P < 0.001)."

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"USP43 promotes proliferation of colorectal cancer cells in vitro."

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"For cell proliferation analysis, USP43 knockdown in SW480 cells could significantly reduce cell proliferation compared with those in normal SW480 cells on days 2, 3, 4, 5 (P < 0.01)."

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"Meanwhile, Figure XREF_FIG C and XREF_FIG D suggested that knockdown and over-expression treatment of ZEB1 gene treatments could effectively inhibit and promote cell proliferation caused by USP43 overexpression and knockdown treatments, respectively."

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"Meanwhile, USP43 overexpression in DLD1 cells could significantly promote cell proliferation in vitro."

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ZEB1 affects USP43

| 1 5

ZEB1 binds USP43. 6 / 6

| 1 5

➶

sparser

"In this study, Co-immunoprecipitation (Co-IP) was employed to study the potential interaction between USP43 protein and ZEB1 protein."

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reach

"ZEB1 can directly interact with USP43 in cellular."

33391437

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sparser

"ZEB1 can directly interact with USP43 in cellular."

33391437

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sparser

"Figure xref F showed that USP43 protein could interact with ZEB1 protein."

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sparser

"Figure xref F and xref G had further identified the interaction between USP43 protein and ZEB1 protein."

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sparser

"Moreover, we have examined the potential interaction between USP43 protein and ZEB1 protein in cellular."

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USP43 is modified

5 | 1

USP43 is phosphorylated.

5 |

USP43 is phosphorylated on S1041. 1 / 1

1 |

➶

hprd

No evidence text available

18669648

USP43 is phosphorylated on S851. 1 / 1

1 |

➶

hprd

No evidence text available

18669648

USP43 is phosphorylated on Y835. 1 / 1

1 |

➶

hprd

No evidence text available

17389395

USP43 is phosphorylated on S848. 1 / 1

1 |

➶

hprd

No evidence text available

18669648

USP43 is phosphorylated on S846. 1 / 1

1 |

➶

hprd

No evidence text available

18669648

USP43 is ubiquitinated.

| 1

USP43 is ubiquitinated. 1 / 1

| 1

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sparser

"Moreover, we have investigated the potential relationships between USP43 ubiquitination and ZEB1 in USP43 overexpression DLD1 cells."

33391437

USP43 affects Neoplasm Invasiveness

| 1 4

USP43 activates Neoplasm Invasiveness. 5 / 5

| 1 4

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"USP43 could promote the proliferation, migration, and invasion of colorectal cancer."

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"USP43 knockdown in SW480 cells could significantly inhibit cell migration and invasion compared to that in the normal SW480 cells (P < 0.01)."

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eidos

"USP43 could promote cell proliferation , invasion , and migration in colorectal cancer by regulating ZEB1 ubiquitylation degradation ."

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reach

"However, USP43 overexpression in DLD1 cells could promote cell migration and invasion compared to that in the normal DLD1 cells (P < 0.01)."

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"Meanwhile, ZEB1overexpression could effectively reverse the changes in invasion caused by USP43 overexpression in SW480 cells (P < 0.01)."

33391437

Valproic acid affects USP43

4 |

Valproic acid increases the amount of USP43. 4 / 4

4 |

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ctd

No evidence text available

26272509

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ctd

No evidence text available

27188386

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ctd

No evidence text available

23179753

➶

ctd

No evidence text available

24383497

USP43 affects VIM

| 4

USP43 increases the amount of VIM. 2 / 2

| 2

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"USP43 knockdown in SW480 cells could effectively inhibit protein expressions of N-cadherin and Vimentin (P < 0.01)."

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"Meanwhile, USP43 knockdown in SW480 cells could inhibit and promote the protein expressions of N-cadherin and Vimentin and protein expressions of N-cadherin, respectively."

33391437

Modified USP43 increases the amount of VIM. 2 / 2

| 2

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"Moreover, USP43 overexpression in DLD1 cells could effectively increase protein expressions of N-cadherin and Vimentin (P < 0.01)."

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"Therefore, USP43 overexpression in DLD1 cells could promote and inhibit the protein expressions of N-cadherin and Vimentin and protein expressions of N-cadherin, respectively."

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USP43 affects CDH2

| 4

Modified USP43 increases the amount of CDH2. 2 / 2

| 2

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"Moreover, USP43 overexpression in DLD1 cells could effectively increase protein expressions of N-cadherin and Vimentin (P < 0.01)."

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"Therefore, USP43 overexpression in DLD1 cells could promote and inhibit the protein expressions of N-cadherin and Vimentin and protein expressions of N-cadherin, respectively."

33391437

USP43 increases the amount of CDH2. 2 / 2

| 2

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"USP43 knockdown in SW480 cells could effectively inhibit protein expressions of N-cadherin and Vimentin (P < 0.01)."

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"Meanwhile, USP43 knockdown in SW480 cells could inhibit and promote the protein expressions of N-cadherin and Vimentin and protein expressions of N-cadherin, respectively."

33391437

Bisphenol A affects USP43

3 |

Bisphenol A decreases the amount of USP43.

2 |

Bisphenol A decreases the amount of USP43. 2 / 2

2 |

➶

ctd

No evidence text available

25181051

➶

ctd

No evidence text available

30816183

Bisphenol A methylates USP43.

1 |

Bisphenol A methylates USP43. 1 / 1

1 |

➶

ctd

No evidence text available

28505145

USP43 affects Cell Survival

| 3

USP43 activates Cell Survival.

| 2

USP43 activates Cell Survival. 2 / 2

| 2

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"The results suggested that USP43 knockdown treated SW480 cells could significantly decrease cell survival in three different drug treatments compared with that in normal SW480 cells (P < 0.05)."

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"However, USP43 overexpression in DLD1 cells could effectively promote cell survival in three different drug treatments compared with that in normal DLD1 cells (P < 0.05)."

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USP43 inhibits Cell Survival.

| 1

USP43 inhibits Cell Survival. 1 / 1

| 1

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"Figure XREF_FIG G and Figure XREF_FIG H suggested that ZEB1 over-expression and knockdown treatments could effectively reverse the changes in cell survival rate caused by USP43 knockdown and overexpression treatment in the chemotherapy sensitivity analysis (P < 0.01)."

33391437

USP43 affects CDH1

1 | 2

USP43 decreases the amount of CDH1.

| 2

Modified USP43 decreases the amount of CDH1. 1 / 1

| 1

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"However, USP43 overexpression in DLD1 cells could effectively inhibit E-cadherin protein expressions (P < 0.01)."

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USP43 decreases the amount of CDH1. 1 / 1

| 1

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"However, USP43 knockdown in SW480 cells could effectively promote protein expressions of E-cadherin (P < 0.01)."

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USP43 binds CDH1.

1 |

CDH1 binds USP43. 1 / 1

1 |

➶

biogrid

No evidence text available

25468996

Vorinostat affects USP43

2 |

Vorinostat increases the amount of USP43. 2 / 2

2 |

➶

ctd

No evidence text available

27188386

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ctd

No evidence text available

26272509

Pirinixic acid affects USP43

2 |

Pirinixic acid decreases the amount of USP43.

1 |

Pirinixic acid decreases the amount of USP43. 1 / 1

1 |

➶

ctd

No evidence text available

19710929

Pirinixic acid activates USP43.

1 |

Pirinixic acid activates USP43. 1 / 1

1 |

➶

ctd

No evidence text available

19710929

Phenylmercury acetate affects USP43

2 |

Phenylmercury acetate increases the amount of USP43. 2 / 2

2 |

➶

ctd

No evidence text available

27188386

➶

ctd

No evidence text available

26272509

P-chloromercuribenzoic acid affects USP43

2 |

P-chloromercuribenzoic acid increases the amount of USP43. 2 / 2

2 |

➶

ctd

No evidence text available

27188386

➶

ctd

No evidence text available

26272509

Entinostat affects USP43

2 |

Entinostat increases the amount of USP43. 2 / 2

2 |

➶

ctd

No evidence text available

26272509

➶

ctd

No evidence text available

27188386

Aflatoxin B1 affects USP43

2 |

Aflatoxin B1 increases the amount of USP43.

1 |

Aflatoxin B1 increases the amount of USP43. 1 / 1

1 |

➶

ctd

No evidence text available

19770486

Aflatoxin B1 decreases the amount of USP43.

1 |

Aflatoxin B1 decreases the amount of USP43. 1 / 1

1 |

➶

ctd

No evidence text available

22100608

USP43 affects cell migration

| 2

USP43 activates cell migration. 2 / 2

| 2

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"USP43 knockdown in SW480 cells could significantly inhibit cell migration and invasion compared to that in the normal SW480 cells (P < 0.01)."

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"However, USP43 overexpression in DLD1 cells could promote cell migration and invasion compared to that in the normal DLD1 cells (P < 0.01)."

33391437

USP43 affects Neoplasm Metastasis

| 2

USP43 inhibits Neoplasm Metastasis. 2 / 2

| 2

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reach

"Meanwhile, previous study indicated that USP43 could remarkably inhibit the growth and metastasis of breast cancer though affecting EGFR/PI3K/AKT XREF_BIBR."

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reach

"We show that USP43 strongly suppresses the growth and metastasis of breast cancer in vivo."

30135474

6-propyl-2-thiouracil affects USP43

2 |

6-propyl-2-thiouracil increases the amount of USP43.

1 |

6-propyl-2-thiouracil increases the amount of USP43. 1 / 1

1 |

➶

ctd

No evidence text available

24780913

6-propyl-2-thiouracil decreases the amount of USP43.

1 |

6-propyl-2-thiouracil decreases the amount of USP43. 1 / 1

1 |

➶

ctd

No evidence text available

25825206

Titanium dioxide affects USP43

1 |

Titanium dioxide increases the amount of USP43. 1 / 1

1 |

➶

ctd

No evidence text available

29264374

Thioacetamide affects USP43

1 |

Thioacetamide increases the amount of USP43. 1 / 1

1 |

➶

ctd

No evidence text available

23411599

Tetrachloromethane affects USP43

1 |

Tetrachloromethane increases the amount of USP43. 1 / 1

1 |

➶

ctd

No evidence text available

31150632

Sulforaphane affects USP43

1 |

Sulforaphane decreases the amount of USP43. 1 / 1

1 |

➶

ctd

No evidence text available

31838189

Sodium dodecyl sulfate affects USP43

1 |

Sodium dodecyl sulfate increases the amount of USP43. 1 / 1

1 |

➶

ctd

No evidence text available

31734321

Rosiglitazone affects USP43

1 |

Rosiglitazone increases the amount of USP43. 1 / 1

1 |

➶

ctd

No evidence text available

21515302

Quinolin-8-ol affects USP43

1 |

Quinolin-8-ol decreases the amount of USP43. 1 / 1

1 |

➶

ctd

No evidence text available

21632981

Quercetin affects USP43

1 |

Quercetin decreases the amount of USP43. 1 / 1

1 |

➶

ctd

No evidence text available

21632981

Paracetamol affects USP43

1 |

Paracetamol decreases the amount of USP43. 1 / 1

1 |

➶

ctd

No evidence text available

29067470

Panobinostat affects USP43

1 |

Panobinostat increases the amount of USP43. 1 / 1

1 |

➶

ctd

No evidence text available

27188386

Nickel monoxide affects USP43

1 |

Nickel monoxide increases the amount of USP43. 1 / 1

1 |

➶

ctd

No evidence text available

19167457

Mercury dibromide affects USP43

1 |

Mercury dibromide increases the amount of USP43. 1 / 1

1 |

➶

ctd

No evidence text available

27188386

Manganese(II) chloride affects USP43

1 |

Manganese(II) chloride increases the amount of USP43. 1 / 1

1 |

➶

ctd

No evidence text available

28801915

Leflunomide affects USP43

1 |

Leflunomide increases the amount of USP43. 1 / 1

1 |

➶

ctd

No evidence text available

28988120

Ketamine affects USP43

1 |

Ketamine decreases the amount of USP43. 1 / 1

1 |

➶

ctd

No evidence text available

20080153

Jinfukang affects USP43

1 |

Jinfukang decreases the amount of USP43. 1 / 1

1 |

➶

ctd

No evidence text available

27392435

Folic acid affects USP43

1 |

Folic acid demethylates USP43. 1 / 1

1 |

➶

ctd

No evidence text available

20938992

Dorsomorphin affects USP43

1 |

Dorsomorphin increases the amount of USP43. 1 / 1

1 |

➶

ctd

No evidence text available

27188386

Decabromodiphenyl ether affects USP43

1 |

Decabromodiphenyl ether increases the amount of USP43. 1 / 1

1 |

➶

ctd

No evidence text available

23914054

Clothianidin affects USP43

1 |

Clothianidin decreases the amount of USP43. 1 / 1

1 |

➶

ctd

No evidence text available

31626844

Cisplatin affects USP43

1 |

Cisplatin decreases the amount of USP43. 1 / 1

1 |

➶

ctd

No evidence text available

27392435

Choline affects USP43

1 |

Choline demethylates USP43. 1 / 1

1 |

➶

ctd

No evidence text available

20938992

Chloroprene affects USP43

1 |

Chloroprene increases the amount of USP43. 1 / 1

1 |

➶

ctd

No evidence text available

23125180

Bis(2-ethylhexyl) phthalate affects USP43

1 |

Bis(2-ethylhexyl) phthalate increases the amount of USP43. 1 / 1

1 |

➶

ctd

No evidence text available

31163220

Acetamide affects USP43

1 |

Acetamide increases the amount of USP43. 1 / 1

1 |

➶

ctd

No evidence text available

31881176

Abrine affects USP43

1 |

Abrine increases the amount of USP43. 1 / 1

1 |

➶

ctd

No evidence text available

31054353

YWHAH affects USP43

1 |

YWHAH binds USP43. 1 / 1

1 |

➶

biogrid

No evidence text available

19615732

YWHAE affects USP43

1 |

YWHAE binds USP43. 1 / 1

1 |

➶

biogrid

No evidence text available

19615732

YWHAB affects USP43

1 |

YWHAB binds USP43. 1 / 1

1 |

➶

biogrid

No evidence text available

19615732

WDR3 affects USP43

1 |

WDR3 binds USP43. 1 / 1

1 |

➶

biogrid

No evidence text available

19615732

Vehicle Emissions affects USP43

1 |

Vehicle Emissions methylates USP43. 1 / 1

1 |

➶

ctd

No evidence text available

25560391

VPS35 affects USP43

1 |

VPS35 binds USP43. 1 / 1

1 |

➶

biogrid

No evidence text available

19615732

USP43 affects migration

| 1

USP43 activates migration. 1 / 1

| 1

➶

eidos

"USP43 could promote cell proliferation , invasion , and migration in colorectal cancer by regulating ZEB1 ubiquitylation degradation ."

33391437

USP43 affects migration invasion colorectal cancer

| 1

USP43 activates migration invasion colorectal cancer. 1 / 1

| 1

➶

eidos

"USP43 could promote the proliferation , migration , and invasion of colorectal cancer ."

33391437

USP43 affects metastasis colorectal cancer Colorectal cancer

| 1

USP43 activates metastasis colorectal cancer Colorectal cancer. 1 / 1

| 1

➶

eidos

"USP43 directly regulates ZEB1 protein , mediating proliferation and metastasis of colorectal cancer Colorectal cancer is one of the most common malignant tumors of the digestive tract ."

33391437

USP43 affects growth metastasis breast cancer

| 1

USP43 inhibits growth metastasis breast cancer. 1 / 1

| 1

➶

eidos

"Meanwhile , previous study indicated that USP43 could remarkably inhibit the growth and metastasis of breast cancer though affecting EGFR / PI3K / AKT 13 ."

33391437

USP43 affects epithelial to mesenchymal transition

| 1

USP43 activates epithelial to mesenchymal transition. 1 / 1

| 1

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reach

"In addition, USP43 could promote tumorigenesis by regulating cell cycle and EMT process in breast cancer XREF_BIBR."

33391437

USP43 affects colorectal cancer cells probe biological function USP43 colorectal cancer cells

| 1

USP43 activates colorectal cancer cells probe biological function USP43 colorectal cancer cells. 1 / 1

| 1

➶

eidos

"USP43 promotes proliferation of colorectal cancer cells in vitro To further probe the biological function of USP43 in colorectal cancer cells , we have studied USP43 expressions in five selected cell lines , including FHC , HCT116 , SW480 , DLD1 , and LOVO ."

33391437

USP43 affects cell cycle

| 1

USP43 activates cell cycle. 1 / 1

| 1

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reach

"In addition, USP43 could promote tumorigenesis by regulating cell cycle and EMT process in breast cancer XREF_BIBR."

33391437

USP43 affects ZEB1 protein

| 1

USP43 inhibits ZEB1 protein. 1 / 1

| 1

➶

eidos

"Moreover , USP43 can reduce ZEB1 protein expression without affecting its transcription ."

33391437

USP43 affects YWHAH

1 |

YWHAH binds USP43. 1 / 1

1 |

➶

biogrid

No evidence text available

19615732

USP43 affects YWHAE

1 |

YWHAE binds USP43. 1 / 1

1 |

➶

biogrid

No evidence text available

19615732

USP43 affects YWHAB

1 |

YWHAB binds USP43. 1 / 1

1 |

➶

biogrid

No evidence text available

19615732

USP43 affects WDR3

1 |

WDR3 binds USP43. 1 / 1

1 |

➶

biogrid

No evidence text available

19615732

USP43 affects VPS35

1 |

VPS35 binds USP43. 1 / 1

1 |

➶

biogrid

No evidence text available

19615732

USP43 affects USP1

1 |

USP1 binds USP43. 1 / 1

1 |

➶

biogrid

No evidence text available

26496610

USP43 affects TXNL4A

1 |

USP43 binds TXNL4A. 1 / 1

1 |

➶

biogrid

No evidence text available

26496610

USP43 affects TRMT6

1 |

USP43 binds TRMT6. 1 / 1

1 |

➶

biogrid

No evidence text available

26496610

USP43 affects TRIM56

1 |

TRIM56 binds USP43. 1 / 1

1 |

➶

biogrid

No evidence text available

26496610

USP43 affects TMEM165

1 |

USP43 binds TMEM165. 1 / 1

1 |

➶

biogrid

No evidence text available

26496610

USP43 affects STX10

1 |

STX10 binds USP43. 1 / 1

1 |

➶

biogrid

No evidence text available

26496610

USP43 affects SSR3

1 |

SSR3 binds USP43. 1 / 1

1 |

➶

biogrid

No evidence text available

26496610

USP43 affects PSME3

1 |

USP43 binds PSME3. 1 / 1

1 |

➶

biogrid

No evidence text available

19615732

USP43 affects PSMA2

1 |

USP43 binds PSMA2. 1 / 1

1 |

➶

biogrid

No evidence text available

26496610

USP43 affects POLD1

1 |

USP43 binds POLD1. 1 / 1

1 |

➶

biogrid

No evidence text available

26496610

USP43 affects PDCD2

1 |

USP43 binds PDCD2. 1 / 1

1 |

➶

biogrid

No evidence text available

19615732

USP43 affects PANC02

| 1

USP43 activates PANC02. 1 / 1

| 1

➶

reach

"USP43 overexpression promoted PANC-1 cell proliferation ( P = 0.0018), but USP43 knockdown decreased PANC02 cell proliferation ( P < 0.001)."

37050932

USP43 affects Osteosarcoma

| 1

USP43 inhibits Osteosarcoma. 1 / 1

| 1

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reach

"Overexpression of the Ubiquitin Specific Proteases USP43, USP41, USP27x and USP6 in Osteosarcoma Cell Lines: Inhibition of Osteosarcoma Tumor Growth and Lung Metastasis Development by the USP Antagonist PR619."

34571917

USP43 affects NPPA

| 1

USP43 binds NPPA. 1 / 1

| 1

➶

sparser

"Three syrup bases were used: a sugar-free vehicle for oral solution (according to USP43-NF38), a vehicle with glucose and hydroxypropyl cellulose (according to the DAC/NRF2018) and a commercially available SyrSpend Alka base."

36986577

USP43 affects NHS

1 |

USP43 binds NHS. 1 / 1

1 |

➶

biogrid

No evidence text available

26496610

USP43 affects NCOA4

1 |

USP43 binds NCOA4. 1 / 1

1 |

➶

biogrid

No evidence text available

26496610

USP43 affects MRPS12

1 |

MRPS12 binds USP43. 1 / 1

1 |

➶

biogrid

No evidence text available

26496610

USP43 affects MAPT

1 |

USP43 binds MAPT. 1 / 1

1 |

➶

biogrid

No evidence text available

26496610

USP43 affects MAGI3

1 |

USP43 binds MAGI3. 1 / 1

1 |

➶

biogrid

No evidence text available

19615732

USP43 affects LCOR

1 |

USP43 binds LCOR. 1 / 1

1 |

➶

biogrid

No evidence text available

26496610

USP43 affects Interferon

| 1

USP43 inhibits Interferon. 1 / 1

| 1

➶

reach

"In the 2 megabases region around MYH13 and MYH8 we found only three genes which could be involved in the fight against SIV: i) Synthaxin 8, a vesicle trafficking protein that functions in the early secretory pathway, ii) USP43 (Ubiquitin-Specific-Processing Protease 43) which negatively regulates type 1 IFN signaling by downregulating the JAK–STAT pathway, iii) ADPRM (ADP-Ribose/CDP-Alcohol Diphosphatase, Manganese Dependent) knockdown of which by shRNA inhibits HIV-1 replication in cultured Jurkat T-cells (PMID: 19460752)."

29739964

USP43 affects INTS1

1 |

USP43 binds INTS1. 1 / 1

1 |

➶

biogrid

No evidence text available

26496610

USP43 affects HAUS5

1 |

USP43 binds HAUS5. 1 / 1

1 |

➶

biogrid

No evidence text available

26496610

USP43 affects FTSJ1

1 |

FTSJ1 binds USP43. 1 / 1

1 |

➶

biogrid

No evidence text available

26496610

USP43 affects FN3KRP

1 |

USP43 binds FN3KRP. 1 / 1

1 |

➶

biogrid

No evidence text available

19615732

USP43 affects EMT

| 1

USP43 activates EMT. 1 / 1

| 1

➶

reach

"We next detected whether USP43 regulated EMT, our results demonstrated that USP43 promoted EMT through regulated snail, thereby facilitated breast cancer cells metastasis."

31966446