IndraLab

Statements


USP43 activates ZEB1. 5 / 5
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"USP43 directly regulates ZEB1 protein, mediating proliferation and metastasis of colorectal cancer."

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"The results suggested that USP43 knockdown treated SW480 cells could significantly promote the degradation of the remaining ZEB1 protein in cells compared to that normal SW480 cells (P < 0.01)."

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"Figure XREF_FIG K and 5L suggested that USP43 overexpression in DLD1 cells could significantly promote the remaining ZEB1 protein in cells compared to that normal DLD1 cells (P < 0.01)."

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"Meanwhile, USP43 knockdown treated SW480 cells could significantly decrease the remaining ZEB1 protein in cells compared to that normal SW480 cells (P < 0.01)."

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"Meanwhile, USP43 overexpression treated DLD1 cells could significantly decrease the degradation of the remaining ZEB1 protein in cells compared to that normal DLD1 cells (P < 0.01)."