IndraLab
Statements
sparser
"Given the facts that phosphorylation of VE-cadherin was enhanced and endocytosis of disassembled VE-cadherin increased when cytoplasmic translocation of exogenous ANG took place, we conclude that, in addition to its angiogenic role, ANG is a key enhancing factor on endothelial barrier dysfunction."
sparser
"By investigating the function and potential effects of this compartmentalized translocation of ANG, we found that rickettisial infection-triggered cytoplasmic translocation of ANG, enhanced phosphorylation of VE-cadherin, reduced VE-cadherin stability, and attenuated endothelial barrier function."