IndraLab

Statements

ANG translocates to the cytoplasm. 24 / 24
| 11 13
sparser
"In addition, nuclear ANG translocates to the cytoplasm [ xref ]."
36361884
reach
"In addition, nuclear ANG translocates to the cytoplasm (Pizzo et al., 2013), which also promotes tiRNA production."
37406666
reach
"This detachment unwinds nuclear ANG, which is then translocated to the cytoplasm to finally generate more tsRNAs."
39199264
reach
"In addition, nuclear ANG translocates to the cytoplasm [4]."
36361884
sparser
"In addition, nuclear ANG translocates to the cytoplasm ( xref ), which also promotes tiRNA production."
37406666
sparser
"In primitive HSCs, which are under hypoxic conditions (an element of generalized cellular stress), angiogenin translocates to the cytoplasm and activates the synthesis of anti-apoptotic genes, suppresses global protein translation, and conserves anabolic energy."
38451606
sparser
"Once exposed to stress stimuli, ANG dissociates from RNH1 and translocates to the cytoplasm for tRNA processing."
36761955
reach
"Under stress conditions such as oxidative stress, hypoxia, and starvation, ANG may translocate to cytoplasm and cleave tRNAs which will result in global translation inhibition (Fig. 3)."
37626421
reach
"Indeed it has been shown that angiogenin promotes rRNA transcription under permissive growth conditions: under stress conditions angiogenin translocates to the cytoplasm reducing protein translation a[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
24412806
reach
"In primitive HSCs, which are under hypoxic conditions (an element of generalized cellular stress), angiogenin translocates to the cytoplasm and activates the synthesis of anti-apoptotic genes, suppresses global protein translation, and conserves anabolic energy."
38451606
sparser
"Indeed it has been shown that angiogenin promotes rRNA transcription under permissive growth conditions: under stress conditions angiogenin translocates to the cytoplasm reducing protein translation a[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
24412806
reach
"Angiogenin promotes homeostasis with its dual function of regulating cell growth when it is in the nucleolus and gets translocated to the cytoplasm in response to stress for damage repair and cell survival."
38961380
reach
"Once exposed to stress stimuli, ANG dissociates from RNH1 and translocates to the cytoplasm for tRNA processing."
36761955
sparser
"Under stress conditions such as oxidative stress, hypoxia, and starvation, ANG may translocate to cytoplasm and cleave tRNAs which will result in global translation inhibition (Fig.  xref )."
37626421
reach
"As a stress activated and secreted ribonuclease, ANG can be transported to the cytoplasm under stress conditions."
32887641
sparser
"However, there is no direct evidence of cytoplasmic translocation of ANG in endothelial cells triggered by adverse events [ xref ]."
23800282
sparser
"By investigating the function and potential effects of this compartmentalized translocation of ANG, we found that rickettisial infection-triggered cytoplasmic translocation of ANG, enhanced phosphorylation of VE-cadherin, reduced VE-cadherin stability, and attenuated endothelial barrier function."
23800282
sparser
"Most importantly, ANG was translocated into the cytoplasm at 48 hrs p.i. (Figure  xref K) and predominated in the cytoplasmic location at 72 hrs p.i. (Figure  xref L)."
23800282
sparser
"Nevertheless, during stress conditions, angiogenin translocate to the cytoplasm and cleaves transfer RNA (tRNA) to produce tRNA-derived, stress-induced small RNAs (tiRNAs) that reduce global protein synthesis but induce the translation of anti-apoptotic factors."
38245670
sparser
"Given the facts that phosphorylation of VE-cadherin was enhanced and endocytosis of disassembled VE-cadherin increased when cytoplasmic translocation of exogenous ANG took place, we conclude that, in addition to its angiogenic role, ANG is a key enhancing factor on endothelial barrier dysfunction."
23800282
sparser
"The mechanism by which SFG rickettsial infection-triggered cytoplasmic translocation of ANG results in phosphorylation of VE-cadherin mediated endothelial barrier dysfunction has yet to be determined."
23800282
sparser
"This detachment unwinds nuclear ANG, which is then translocated to the cytoplasm to finally generate more tsRNAs."
39199264
reach
"When stress occurs, the cytoplasmic concentration of active ANG increases, coming from ANG–RNH1 complex dissociation, nuclear ANG translocation to the cytoplasm, and ANG transcription induction (Lyons et al., 2017)."
35463945
reach
"Usually, angiogenin is located in the nucleus, but is released into the cytoplasm under certain stress conditions."
29107107