IndraLab

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ANG translocates from the nucleus. 7 / 7
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"Accordingly, our results suggest that exposure to environmental stressors such as LPS or PA weaken the binding and interaction between RNH1 and ANG, resulting in the release of ANG from the nucleus and increases in the levels of both ANG and tsRNAs in the cytoplasm of EEC."
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"In response to stress, ANG translocates into cytoplasm from the nucleus and dissociates from RNH1."
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"Oxidative stress reportedly alters the localization of RNases; Rny1 in yeast diffuses from the vacuole to the cytoplasm [7] and ANG in mammalian cells translocates from the nucleus to SGs [13] ."
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"At the same time, under stress conditions, ANG translocates from the nucleus and accumulates in the cytoplasm, slicing mature tRNAs to produce tiRNAs [ xref ]."
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"The release of nuclear angiogenin from the nucleus by DNase I indicates that it can directly bind to nuclear DNA."
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"Several stressors induce ANG translocation from the nucleus into the cytoplasm, where it cleaves transfer RNAs (tRNAs) in the anticodon loop to produce tRNA derived stress induced RNA (tiRNAs) [XREF_BIBR, XREF_BIBR]."
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"These findings suggest that age-dependent cleavage of tRNA Glu relies on the translocation of ANG from the nucleus to the cytoplasm.Phosphorylation status is a major determinant for the cellular distr[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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