IndraLab

Statements

ANG translocates to the nucleolus. 4 / 4
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"Angiogenin, produced by KSHV infection, translocates to the nucleolus and increases the production of rRNA to enhance the survival of the infected endothelial cell [70]."
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"Specifically, the infection of endothelial cells with KSHV induces the expression and secretion of the angiogenesis factor Angiogenin, which in turn translocates into the nucleus and to the nucleolus of subconfluent cells, stimulates proliferation and 45S rRNA gene transcription, and inhibits apoptosis [50]."
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"To promote cell growth and proliferation, angiogenin translocates to the nucleus and nucleolus where it stimulates rRNA transcription."
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"ANG binds to endothelial cells and translocates to nucleolus where it binds to DNA."
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