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E2F7 activates USP47. 3 / 3

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eidos

"E2F7 upregulated USP47 expression by downregulating miR-199b in SW403 cells ."

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eidos

"USP47 upregulation by E2F7 deubiquitin-modifies MAPK K48 ubiquitin chain to stabilize MAPK ."

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"Therefore, we are convinced that present results show that E2F7 suppressed the miR-199b expression and promoted USP47 to stabilize MAPK proteins, thereby contributing to colon cancer development."

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E2F7 activates USP47. 3 / 3

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