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STAMBP inhibits K63-linked ubiquitin chain NLRP3. 1 / 1
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eidos
"The difference is that STAMBP does not affect the protein abundance of NLRP3 , but STAMBP deficiency enhances the K63-linked ubiquitin chain of NLRP3 , and the non-degraded STAMBP ubiquitination process favors NLRP3 inflammasome activation ( Bednash et al ., 2021 ) ."