IndraLab

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KCNQ1 activates Kv7.1. 2 / 2
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"Long QT Syndrome type 1 (LQT1), an inherited cardiac ion channelopathy associated with arrhythmias and risk of sudden death, is caused by mutations in KCNQ1 encoding the alpha-subunit of Kv7.1, that affects the slow component of delayed rectifier K + current (I Ks) channel."

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"Next, we need to conduct experiments to verify the dysfunction of Kv7.1 induced by KCNQ1 gene mutations and explore the mechanism of deafness."