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OTUB1 activates HSF1 protein stability. 4 / 4
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eidos
"Here , we demonstrate that OTUB1 interacts with HSF1 and promotes HSF1 protein stability through deubiquitination ."

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"And OTUB1 promoted HSF1 protein stability in dependence on its deubiquitinating enzyme activity ( Figure 2C ) ."

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"In summary , OTUB1 promotes the HSF1 protein stability through the deubiquitination pathway ."

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"OTUB1 promotes HSF1 protein stability via the ubiquitin-proteasome pathway Ovarian tumor B1 enhances heat shock transcription factor 1 transcriptional activity OTUB1 promoted the protein stability of HSF1 , so we next determined whether OTUB1 could regulate HSF1-mediated transcription ."