IndraLab

Statements

AKT decreases the amount of USP12. 2 / 2

| 2

reach

"Consistently, ectopic expression of the myristoylated form of AKT1 (myr-AKT1) significantly repressed USP12 expression in both human and mouse tumour cells (Fig. 1k); knockdown of endogenous AKT1 or AKT2, the two major isoforms of AKT, induced higher levels of USP12 than did the control treatment (Fig. 1l)."

34381028

➶

reach

"Furthermore decreasing the levels of Usp12 was shown to sensitize prostate cancer cells to therapeutics which target Akt (McClurg et al., 2014)."

26525204

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

AKT decreases the amount of USP12. 2 / 2

INDRA sources:

Databases

Reading