IndraLab

Statements


USP28 activates miR-3940-5p. 7 / 7
| 7

reach
"CCND1 and USP28 Are Targets of miR-3940-5p."

reach
"In combination with a significant negative correlation between expressions of miR-3940-5p versus CCND1 mRNA and USP28 mRNA in NSCLC tissues, these results suggest that CCND1 and USP28 are functional targets of miR-3940-5p and miR-3940-5p affects proliferation and apoptosis in A549 cells by targeting CCND1 and USP28."

reach
"We searched for miR-3940-5p targets by using TargetScan and miRanda online tools and found that CCND1 and USP28 were potential targets of miR-3940-5p."

reach
"However, overexpression of CCND1 and USP28 fails to fully restore the effect of miR-3940-5p on proliferation and apoptosis probably due to a sufficiently high endogenous level of CCND1 and USP28 already existing in A549 cells."

reach
"Furthermore, we verified that CCND1 and USP28 were direct targets of miR-3940-5p and also found that the effects of NSCLC cell proliferation and apoptosis by miR-3940-5p were attenuated by overexpression of CCND1 or USP28."

reach
"We searched the TargetScan and miRanda databases and found that CCND1 and USP28 are potential targets of miR-3940-5p."

reach
"It was verified that CCND1 and USP28 were direct targets of miR-3940-5p, and the phenotypes of NSCLC cell proliferation and apoptosis imposed by miR-3940-5p could be attenuated by overexpression of CCND1 or USP28."