IndraLab

Statements

ATXN3 activates VCP. 5 / 5
| 5
reach
"In contrast, evidence has also shown that ataxin-3 may promote p97 associated deubiquitination to facilitate the transfer of ERAD substrates to the proteasome XREF_BIBR."
25013401
reach
"Various ataxin-3 protein domains contribute to its toxicity, including the valosin-containing protein (VCP)-binding motif (VBM)."
34563642
reach
"In this scenario, ATX3 promotes sufficient p97‐dependent extraction of RNF8 in a classical ERAD‐like manner (Wang et al, 2006; Zhong & Pittman, 2006)."
31613024
reach
"We present evidence that atx3 may promote p97 associated deubiquitination to facilitate the transfer of polypeptides from p97 to the proteasome."
17000876
reach
"Atx3 promotes p97 associated deubiquitination."
17000876