IndraLab

Statements

Lactate inhibits IFNB1. 3 / 3
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eidos
"Lactate induced HBV replication and inhibited IFN-beta expression ; however , this effect was markedly reduced by an MCT1 knockdown ( Supplementary Fig. 6f-h ) , suggesting that lactate transport into cells is essential for HBV-mediated immune escape ."
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"Moreover, lactate addition in Ldha -/- macrophage consistently reduced IFN-beta production (XREF_FIG)."
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"In addition, administration of sodium lactate in mice reduced production of IFN-b."
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