IndraLab

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UCHL3 binds GARS1. 5 / 5
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"The protein‒protein docking results from Alphafold 2 revealed that UCHL3 could directly bind with SMAD1 through hydrogen bonds (Fig. 7i)."
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"Further immunofluorescence and co-immunoprecipitation (Co-IP) verified the interaction between UCHL3 and SMAD1 in BMSCs (Fig. 7j–l)."
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"To investigate the interaction between Uch-L3 and Smad1, HA-Smad1 and Flag-Uch-L3 plasmids were transfected into HEK 293 cells."
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"All of these results showed that Uch-L3 interacts with Smad1.After confirming the interaction between Smad1 and Uch-L3, we tested whether the deubiquitinating activity of Uch-L3 is able to affect the [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"The physical interaction between Uch-L3 and Smad1 was revealed."
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