IndraLab

Statements

Oclacitinib inhibits JAK1. 6 / 8
2 | 6
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"Oclacitinib inhibits JAK1 and JAK2 activation."
32548076
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"Oclacitinib also inhibited the function of JAK1 dependent cytokines involved in allergy and inflammation (IL-2, IL-4, IL-6, and IL-13) as well as pruritus (IL-31) at IC 50 's ranging from 36 to 249nm."
24495176
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"Oclacitinib selectively inhibits Janus kinase 1."
23829933
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"Oclacitinib inhibited JAK1, JAK2, JAK3, and TYK2 by 50% at concentrations (IC 50 's) of 10, 18, 99, and 84nm, respectively."
24495176
reach
"Oclacitinib is a selective inhibitor of Janus kinase 1, licensed for the treatment of clinical signs of canine atopic dermatitis and allergic pruritus in dogs [189]."
37835664
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"Oclacitinib is a selective inhibitor of janus kinase 1."
30323921