IndraLab

Statements

Resveratrol inhibits MYD88. 8 / 9
1 | 8
reach
"Zhang et al. found that resveratrol can inhibit the production of inflammatory cytokines by regulating the TLR4, MyD88, and NF-κB signaling pathways (44)."
34988180
reach
"Specific inhibition of MyD88 independent signaling pathways of TLR3 and TLR4 by resveratrol : molecular targets are TBK1 and RIP1 in TRIF complex."
16116226
reach
"Resveratrol was also found to impairs TLR4 and TLR3 pathways independent of MyD88 signaling [174]."
34439920
reach
"For example tumor growth factor-beta selectively inhibits the MyD88 dependent pathway and the natural product resveratrol has been shown to selectively inhibit the MyD88 independent pathway (TRIF)."
20006962
reach
"In human chondrocytes, resveratrol can remarkably suppress the upregulation of TLR4 and the downstream target MyD88 and TRAF6 induced by IL-1beta [XREF_BIBR]."
28203259
reach
"Resveratrol was also shown to inhibit MyD88-independent signaling pathways and target expression through (TANK)-binding kinase 1 (TBK1) and RIP1 in the TRIF complex [18] ."
22925919
reach
"Furthermore, the suppressive effect of resveratrol on LPS induced NF-kappaB activation was abolished in TRIF deficient mouse embryonic fibroblasts, but not in MyD88 deficient macrophages (XREF_FIG), suggesting that resveratrol specifically inhibits MyD88 independent signaling pathways downstream of TLR3 and TLR4."
21631512
reach
"Specific inhibition of MyD88 independent signaling pathways of TLR3 and TLR4 by resveratrol : Molecular targets are TBK1 and RIP1 in TRIF complex."
16455582