IndraLab

Statements

Resveratrol inhibits MYD88. 6 / 6
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ctd
No evidence text available
24617573
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"Resveratrol was also found to impairs TLR4 and TLR3 pathways independent of MyD88 signaling [174]."
34439920
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"In human chondrocytes, resveratrol can remarkably suppress the upregulation of TLR4 and the downstream target MyD88 and TRAF6 induced by IL-1beta [XREF_BIBR]."
28203259
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"For example tumor growth factor-beta selectively inhibits the MyD88 dependent pathway and the natural product resveratrol has been shown to selectively inhibit the MyD88 independent pathway (TRIF)."
20006962
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"Specific inhibition of MyD88 independent signaling pathways of TLR3 and TLR4 by resveratrol : molecular targets are TBK1 and RIP1 in TRIF complex."
16116226
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"Furthermore, the suppressive effect of resveratrol on LPS induced NF-kappaB activation was abolished in TRIF deficient mouse embryonic fibroblasts, but not in MyD88 deficient macrophages (XREF_FIG), suggesting that resveratrol specifically inhibits MyD88 independent signaling pathways downstream of TLR3 and TLR4."
21631512