IndraLab

Statements


COPS5 increases the amount of STAT3. 3 / 3
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"In order to delineate whether Stat3 regulates Jab1 transcription, we performed a luciferase reporter assay with 5 ' deletion analysis of the human Jab1 promoter."

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"JAB1 knockdown decreased unphosphorylated STAT3 DNA binding activity, but tends to increase nuclear STAT3 expression level."

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"Because Stat3 expression in NPC was associated with Jab1 expression, we sought to determine whether the overexpression of Stat3 could enhance Jab1 transcription in NPC cells."