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OTUB1 inhibits G1 phase. 4 / 4
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"Furthermore, the cell cycle analysis showed that OTUB1 depletion could induce G1 phase arrest, which could be partially rescued by further YAP-S5A over-expression in MKN28 cells (Supplementary Fig. 3E, F)."
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"Silencing OTUB1 promotes apoptosis and cell cycle arrest at G1 phase, inhibiting cell proliferation."
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"Besides, the cell cycle analysis showed that OTUB1 depletion could induce G1 phase arrest, which could be partially rescued by further YAP over-expression in MKN28 cells (Fig. 4I, J)."
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"Silencing OTUB1 induced G1 phase arrest and increased the proportion of apoptotic cells (Figures 2E and F; Figures S2C and D)."
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