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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

MYC activates COPS6. 3 / 3

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"CSN6 increase Myc stability by reducing Myc ubiquitination."

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"A recent study also demonstrated that CSN6 contributed to carcinogenesis by positive regulation of Myc stability."

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"As expected, Myc mediated transcriptional activation target CDK4 and Myc mediated transcriptional repression targets p27Kip1 and p21Cip1 were deregulated in Emicro-Myc and Csn6 +/- lymphomas compared to Emicro-Myc and Csn6 +/+ lymphomas (XREF_FIG)."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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Statements

MYC activates COPS6. 3 / 3

Our Sources:

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