IndraLab

Statements


MYC activates COPS6. 3 / 3
| 3

reach
"As expected, Myc mediated transcriptional activation target CDK4 and Myc mediated transcriptional repression targets p27Kip1 and p21Cip1 were deregulated in Emicro-Myc and Csn6 +/- lymphomas compared to Emicro-Myc and Csn6 +/+ lymphomas (XREF_FIG)."

reach
"A recent study also demonstrated that CSN6 contributed to carcinogenesis by positive regulation of Myc stability."

reach
"CSN6 increase Myc stability by reducing Myc ubiquitination."