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Heat-Shock Proteins activates UCHL5. 1 / 1
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"In contrast , C-CBL , heat shock protein 90 ( Hsp90 ) , transforming growth factor-beta stimulated clone 22 ( TSC-22 ) , tumor necrosis factor receptor-associated factor 4 ( TRAF4 ) , ubiquitin-specific protease 4 ( USP4 ) , ubiquitin-specific protease 11 ( USP11 ) , ubiquitin-specific protease 15 ( USP15 ) , and UCH37 can stabilize the receptor by blocking the ubiquitination of the receptor [ 103-110 ] , thereby activating the TGF-beta signaling pathway ."