IndraLab

Statements

Ponatinib inhibits KCNH2. 2 / 2

| 2

reach

"71 The exception seems to be ponatinib, which inhibited hERG at concentrations above 1muM, substantially in excess of the steady-state maximal concentrations observed in patients treated at the clinical dose of 45mg."

27121688

➶

reach

"However, ponatinib and imatinib significantly decreased the polarization of the hERG channel."

31837444

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

Ponatinib inhibits KCNH2. 2 / 2

INDRA sources:

Databases

Reading