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KCNMA1 activates GZMB. 3 / 3
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"BNIP-2 cleavage upon SLO mediated GrB delivery in cellulo."
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"Furthermore, BNIP-2 cleavage in a cellular context was shown to occur upon SLO mediated GrB delivery, hinting to its physiological relevance."
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"To assess if our in vitro findings can be extrapolated to cell cultures and to corroborate the results reported by Scott et al. [XREF_BIBR] who demonstrated cleavage of hBNIP-2 by hGrB during natural killer mediated cell death, we pursued GrB cleavage of overexpressed human and mouse BNIP-2 by means of SLO mediated GrB delivery in HeLa and NIH/3T3 cells respectively."
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