IndraLab

Statements

USP9X decreases the amount of VHL. 3 / 3
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reach
"As knockdown of USP9X in HEK293T cells significantly increased pVHL levels, both mRNA levels and protein half-life of pVHL were evaluated in HEK293T cells to further investigate the mechanism by which USP9X regulates pVHL."
27517496
reach
"This study shows that inhibition of USP9X function by either shRNA or a chemical inhibitor significantly enhances pVHL levels and suppresses tumor cell proliferation."
27517496
reach
"USP9X negatively regulates pVHL levels and consequently protects HIF and NF-kappaB activity."
27517496