IndraLab

Statements

Modified USP7 increases the amount of TP53. 2 / 2

| 2

reach

"In addition, USP7 overexpression significantly increased endogenous Mdm2 and p53 levels, but had no effect on STIP levels (XREF_SUPPLEMENTARY)."

26460617

➶

reach

"Expression of USP7, the target protein of EBNA1 and ICP0, however, effectively promotes increased levels of p53 by antagonizing proteasomal degradation of p53 through deubiquitination."

17291557

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

Modified USP7 increases the amount of TP53. 2 / 2

INDRA sources:

Databases

Reading