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INS activates USP7. 2 / 2

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"We also performed pull-down analysis using the MATH domain of USP7 as a bait and IRS-2 derived from H4IIE cells treated with or without insulin as a prey."

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reach

"We also demonstrate that insulin or IGF-I treatment stimulates USP7 dissociation from IRSs via activation of PI3K pathway, leading to degradation of IRSs."

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IndraLab

Statements

INS activates USP7. 2 / 2

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