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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

INS activates USP7. 2 / 2

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"We also performed pull-down analysis using the MATH domain of USP7 as a bait and IRS-2 derived from H4IIE cells treated with or without insulin as a prey."

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"We also demonstrate that insulin or IGF-I treatment stimulates USP7 dissociation from IRSs via activation of PI3K pathway, leading to degradation of IRSs."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...