IndraLab

Statements

USP4 deubiquitinates insulin receptors. 4 / 4
| 4
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"USP4 further reduces the ubiquitination of insulin receptors and increases their expression."
40133964
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"Additionally, USP4 decreases the ubiquitination and degradation of insulin receptors, consequently leading to reduced insulin resistance (118)."
38322269
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"Upregulation of USP4 reduces the ubiquitination and degradation of insulin receptors, upregulates the level of insulin receptors, and ultimately improves insulin resistance."
34603025
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"USP4 is a deubiquitinating enzyme and may deubiquitinate insulin receptors to inhibit their degradation, which maintains the expression level of insulin receptors on the membrane surface and improves insulin resistance."
34603025