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TP53BP1 inhibits USP28. 2 / 2

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"Incubation of total cell lysates with the Ub-VME/Ub-VS probes showed that depletion of 53BP1 stimulated USP28 deubiquitinase activity (Figure 5D, Supplementary Figure S5G), whereas the abundance of USP28 was not changed (Supplementary Figure S5H and I)."

38227944

➶

reach

"We concluded that depletion of 53BP1 promotes formation of USP28 monomers and stabilizes MYC."

38227944

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IndraLab

Statements

TP53BP1 inhibits USP28. 2 / 2

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