IndraLab

Statements


Modified USP22 increases the amount of TERF1. 2 / 2
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"Conversely, overexpression of wild-type (but not catalytically inactive) USP22 leads to increased TRF1 levels."

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"Furthermore, expression of wt-USP22, but not the C185S mutant, was able to partially restore TRF1 levels in cells depleted for endogenous USP22 (XREF_FIG, compare panels 4, 5 and 6)."