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USP46 increases the amount of CTNNB1. 1 / 1

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"We found that knockdown of USP46 decreased the viability of intestinal organoids and LRP6 and β-catenin levels (Fig. 5F and Supplementary Fig. 7A, B) and that this effect was more evident at lower concentrations of RSPO (corresponds to higher RNF43/ZNRF3 activities)."

37798301

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IndraLab

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USP46 increases the amount of CTNNB1. 1 / 1

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