IndraLab

Statements

CYLD activates CXCL8. 2 / 2
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"In the present study, we found that high glucose dose- and time-dependently downregulated the protein and mRNA expressions of CYLD in GMCs (SV40 MES 13 and HBZY-1) and increased the expression levels of p-IkappaBalpha, NF-kappaBp65, and p-NF-kappaBp65, and furthermore induced the release of MCP-1, IL-6, and IL-8."
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"CYLD induction mediated, at least in part, the TZD mediated downregulation of tumor necrosis factor alpha (TNFalpha)-induced interleukin 8 (IL-8)."
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