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Metformin inhibits NFKBIA. 2 / 2

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"In addition, metformin suppressed the transcription activity of NF-kappaB by inhibiting the degradation of IkappaBalpha."

30520054

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"Along with the upregulation of phosphorylated AMPKalpha and ACCalpha, metformin at 1.5 and 3mM inactivated NF-kappaB signalling components (p65 and IkappaBalpha) and the inflammatory genes (TNFA, IL6, IL1B and COX-2) which were activated by BHBA."

33982074

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IndraLab

Statements

Metformin inhibits NFKBIA. 2 / 2

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