IndraLab

Statements

KCNMA1 decreases the amount of calcium(2+). 3 / 3
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"BK channel activation can hyperpolarize the cell resting membrane potential (RMP), decrease the intracellular Ca level, and attenuate UBSM cell excitability, therefore cause UBSM relaxation."
| PMC
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"To determine whether SLO perturbs calcium levels within cardiac cells, contractility and intracellular calcium were simultaneously measured in primary cardiomyocytes loaded with the fluorescent calcium indicator dye, Fura-2."
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"Using Fura-2AM to monitor intracellular Ca (2+), it was observed that inhibition of the BK channel during glutamate induced depolarization led to an additive increase in intracellular Ca (2+) levels."
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