IndraLab

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USP15 activates YY1. 2 / 2
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"These results support the possibility that USP15 forms a complex with YY1.3.8 YY1 knockdown rescued the inhibitory effects of USP15 on HIV-1 gene expression and virus production, while USP15 knockdown led to decreased YY1 and increased HIV-1 gene expression and virus production."

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"In the meantime, we confirmed YY1 and USP15 expression and the changes in YY1 induced by USP15 expression ( Figures 10C–F )."